Catalysis-chemistry

Kusurkar, Radhika S. published the artcileMicrowave-assisted conjugate addition of pyrrole on electron-deficient nitro-olefins, HPLC of Formula: 4230-93-7, the publication is Synthetic Communications (2010), 40(3), 320-327, database is CAplus.

Michael addition of pyrrole to β-nitrovinyl compounds were carried out using microwave methodol. Monosubstituted pyrroles were obtained selectively in a major amount Formation of novel product obtained during one of the reactions was explained by the double addition to nitrostyrene.

Synthetic Communications published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, HPLC of Formula: 4230-93-7.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tomazin, Ursa published the artcileSynthesis of polyenaminones by acid-catalyzed amino-enaminone ‘click’ polymerization, COA of Formula: C3H12Cl2N2, the publication is European Polymer Journal (2018), 603-616, database is CAplus.

A mild amino-enaminone ‘click’ polymerization method for the preparation of polyenaminones by transamination of α,α’-bis-enaminocyclopentanones with diamines was developed. A series of 12 representative polymers were synthesized by acid-catalyzed transamination of two bis-enaminones with six primary 1,2-, 1,3-, and 1,4-diamines. The method allows for combinatorial preparation of structurally diverse polyenaminones from easily available diamines and bis-enaminones. The reaction mechanism was studied by NMR and MS. It involves formation of open-chain and cyclic oligomers, which then undergo a step-wise polymerization to furnish the title polymers with high average mol. weight (M_w > 5.0 × 10⁴ Da) and with spherical and porous microstructure. The obtained polymers were insoluble in most organic solvents, stable in diluted acids and bases, while degradable in concentrated hydrochloric acid at room temperature They were thermally stable up to 200 °C and exhibited film-forming and UV-vis-shielding properties.

European Polymer Journal published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C7H8INO, COA of Formula: C3H12Cl2N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rezaei, Fahimeh published the artcileDesign and synthesis of Fe₃O₄@SiO₂/aza-crown ether-Cu(II) as a novel and highly efficient magnetic nanocomposite catalyst for the synthesis of 1,2,3-triazoles, 1-substituted 1H-tetrazoles and 5-substituted 1H-tetrazoles in green solvents, HPLC of Formula: 5411-14-3, the publication is Inorganica Chimica Acta (2019), 8-18, database is CAplus.

A New and efficient magnetic nanocatalyst was fabricated via covalent grafting of an aza-crown ether Cu(II) complex on silica coated iron oxide support. The above mentioned magnetic nanocatalyst was characterized by various techniques such as SEM, TEM, XRD, FT-IR, TGA and ICP. After preparation, the applicability of this catalyst in the synthesis of triazole and tetrazole derivatives was studied. The prominent features of the present methodol. are: high yields, short reaction times, easy preparation, magnetical separation and favorable recoverability of the catalyst (for at least five runs without significant loss of catalytic activity).

Inorganica Chimica Acta published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, HPLC of Formula: 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Drayton, Matthew published the artcileEnzymatically releasable polyethylene glycol – host defense peptide conjugates with improved activity and biocompatibility, Formula: C20H19NO4, the publication is Journal of Controlled Release (2021), 220-231, database is CAplus and MEDLINE.

Host defense peptides (HDPs) have been the subject of great interest for the treatment of multidrug-resistant bacterial infections due to their multimodal activity and low induction of resistance. However, aggregation, toxicity, and short biol. half-life have limited their applicability for clin. treatment. Many methods have been explored to alleviate these issues, such as polymer (e.g., polyethylene glycol (PEG)) conjugation, but these are often accompanied by reductions in the activity of the HDP. Here, we detail the design of a novel PEG-HDP conjugate incorporating an enzymic cleavage sequence targeting matrix metalloproteinases (MMPs) that accumulate at sites of inflammation and infection. Addition of the cleavage sequence onto either the N- or the C-terminal region of the parent peptide (peptide 73, a derivative of the HDP aurein 2.2) was explored to determine the location for optimal antimicrobial activity following MMP cleavage; furthermore, the susceptibility of the peptide to MMP cleavage after conjugation to 2 kDa or 5 kDa PEG was examined The top candidate, L73, utilized an N-terminal cleavage site that was subsequently conjugated to a 2 kDa PEG polymer. Both L73 and the conjugate exhibited no antimicrobial activity in vitro until cleaved by purified MMP, which liberated a peptide fragment with 16- or 63-fold improved activity, resp., corresponding to a min. inhibitory concentration (MIC) of 8 μg/mL, comparable to that of peptide 73 (4 μg/mL). Furthermore, PEG conjugation improved the blood compatibility and reduced the aggregation tendency of the HDP in vitro, indicating enhanced biocompatibility. When administered as a single s.c. dose (âˆ?.6 mg, or a peptide concentration of 142 mg/kg) in a mouse abscess model of high-d. methicillin-resistant Staphylococcus aureus (MRSA) infection, the conjugate displayed strong activity, reducing abscess size and bacterial load by 73.3% and 58-fold, resp. This activity was completely lost when the cleavage site was rendered resistant to MMPs by the substitution of two D-amino acids, supporting the hypothesis that antimicrobial activity was dependent on cleavage by MMPs, which were shown here to increasingly accumulate at the abscess site up to 18 h post infection. Finally, the conjugate displayed biocompatibility in vivo, with no identifiable toxicity or aggregation.

Journal of Controlled Release published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Formula: C20H19NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yost, Julianne M. published the artcileDirect carbon-carbon bond formation via soft enolization: aldol addition of α-halogenated thioesters, Application of 2,4,6-Triisopropylbenzenethiol, the publication is Chemical Communications (Cambridge, United Kingdom) (2011), 47(1), 571-572, database is CAplus and MEDLINE.

α-Halo thioesters undergo soft enolization and syn-selective direct aldol addition to aldehydes in the presence of MgBr₂·OEt₂ and i-Pr₂NEt to produce α-halo-β-hydroxy thioesters, e.g., I.

Chemical Communications (Cambridge, United Kingdom) published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C27H39ClN2, Application of 2,4,6-Triisopropylbenzenethiol.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Trisunaryanti, Wega published the artcileEffective production of biofuel from used cooking oil over Ni-Pd loaded on amine-functionalized Lapindo Mud catalyst, Recommanded Product: 3-(Trimethoxysilyl)propan-1-amine, the publication is Reaction Kinetics, Mechanisms and Catalysis (2022), 135(2), 951-970, database is CAplus.

In the present work, Lapindo Mud (LL) as natural-based catalyst support material without any prior chem. extraction obtained from Sidoarjo, East Java comprising SiO₂ (45.49%), Al₂O₃ (13.82%), and Fe₂O₃ (21.63%) was impregnated with the combination of Ni and/or Pd metal catalyst (i.e. LL, Ni/LL, Pd/LL, Ni-Pd/LL). The modification of heterogeneous catalyst (catalyst-support material) by the addition of amine-functionalized group from 3-APTMS compound (i.e. NH₂/LL, Ni-NH₂/LL, Pd-NH₂/LL, and Ni-Pd-NH2/LL) to improve catalyst activity and selectivity towards Free Fatty Acid (FFA) in the hydro-treatment process of used cooking oil into biofuel was thoroughly compared. The result found that Ni-Pd-NH₂/LL catalyst was able to generate the higher conversion of liquid product and to decrease the generation of FFA from 10.1 to 3.2% compared to the un-grafted Ni-Pd/LL catalyst. The study showed that the optimum temperature to produce hydrocarbons in hydro-treatment process using Ni-Pd-NH₂/LL catalyst was at 550°C with 1/100 catalyst-to-feed weight ratio.

Reaction Kinetics, Mechanisms and Catalysis published new progress about 13822-56-5. 13822-56-5 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is 3-(Trimethoxysilyl)propan-1-amine, and the molecular formula is C6H12F3NO5S, Recommanded Product: 3-(Trimethoxysilyl)propan-1-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Benzaoui, Karim published the artcileElectromagnetic interference shielding effectiveness of polypyrrole-silver nanocomposite films on silane-modified flexible sheet, HPLC of Formula: 13822-56-5, the publication is High Performance Polymers (2022), 34(3), 310-320, database is CAplus.

The conventional electromagnetic interference (EMI) shielding materials are being gradually replaced by a new generation of supported conducting polymer composites (CPC) films due to their many advantages. This work presents a contribution on the effects of silane surface-modified flexible polypyrrole-silver nanocomposite films on the electromagnetic interference shielding effectiveness (EMI-SE). Thus, the UV-polymerization was used to in-situ deposit the PPy-Ag on the biaxial oriented polyethylene terephthalate (BOPET) flexible substrates whose surfaces were treated by 3-aminopropyltrimethoxysilane (APTMS). XPS analyzes confirmed the APTMS grafting procedure. Structural, morphol., thermal, and elec. characteristics of the prepared films were correlated to the effect of substrate surface treatment. Thereafter, EMI-SE measurements of the elaborated films were carried out as per ASTM D4935 standard for a wide frequency band extending from 50 MHz to 18 GHz. The obtained results confirmed that the APTMS-treated BOPET film exhibit higher EMI shielding performance and better elec. characteristics compared to the untreated film. In fact, a 32% enhancement of EMI-SE was noted for the treated films compared to the untreated ones. Overall, these results put forward the role played by the surface treatment in strengthening the position of flexible PPy-Ag supported films as high-performance materials in electronic devices and electromagnetic interference shielding applications.

High Performance Polymers published new progress about 13822-56-5. 13822-56-5 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is 3-(Trimethoxysilyl)propan-1-amine, and the molecular formula is C6H17NO3Si, HPLC of Formula: 13822-56-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Postma, Tobias M. published the artcileN-Chlorosuccinimide, an Efficient Reagent for On-Resin Disulfide Formation in Solid-Phase Peptide Synthesis, Category: catalysis-chemistry, the publication is Organic Letters (2013), 15(3), 616-619, database is CAplus and MEDLINE.

N-Chlorosuccinimide is described as a widely applicable on-resin disulfide-forming reagent. Disulfide bond formation was completed within 15 min in DMF. This strategy was successfully used in the synthesis of oxytocin and a regioselective synthesis of an α-conotoxin. Moreover, disulfide formation with N-chlorosuccinimide was found to be compatible with oxidation-prone methionine and tryptophan.

Organic Letters published new progress about 77189-99-2. 77189-99-2 belongs to catalysis-chemistry, auxiliary class Thiophenol,Benzene,Ether, name is 2,4,6-Trimethoxybenzenethiol, and the molecular formula is C9H12O3S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chakraborty, Amit published the artcileChemoselective disulfide formation by thiol-disulfide interchange in SIT-protected cysteinyl peptides, Quality Control of 71989-31-6, the publication is Journal of Organic Chemistry (2022), 87(1), 708-712, database is CAplus and MEDLINE.

Chemoselective disulfide formation is accomplished through a thiol-disulfide interchange approach using sec-isoamyl mercaptan (SIT) as an alkyl sulfenyl-protecting group of one of the Cys residues involved in the pairing. SIT has a dual and unique characteristic, acting as a masking group during the synthesis and directing disulfide formation in the presence of a free thiol. This novel approach is illustrated by the synthesis of several peptides of biol. interest.

Journal of Organic Chemistry published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Quality Control of 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Voronkov, M. G. published the artcileReaction of phenyltrifluorosilane and phenyl(hydrocarbyl)difluorosilanes with bis(2-hydroxyethyl)-and tris(2-hydroxyethyl)amine and their N-methyl and O-trimethylsilyl derivatives. A novel route to quasisilatranes, Application In Synthesis of 312-40-3, the publication is Russian Journal of General Chemistry (2006), 76(12), 1854-1859, database is CAplus.

Reaction of phenyltrifluorosilane, diphenyldifluorosilane, and methylphenyldifluorosilane with bis(2-hydroxyethyl)amine, Me-bis(2-hydroxyethyl)amine, Me-bis(2-trimethylsiloxyethyl)amine, leads to 1,3-dioxa-6-aza-2-silacyclooctane derivatives, (N→Si) quasisilatranes: 1,1-difluoroquasisilatrane, 1-phenyl-1-fluoro-5-methylquasisilatrane, or 1-methyl-1-fluoroquasisilatrane, containing the donor-acceptor bond N→Si and pentacoordinate Si atom. 1-Phenylsilatrane is the product of the reaction of phenyltrifluorosilane with tris(2-trimethylsiloxyethyl)amine, whereas with tris(2-hydroxyethyl)amine 1-phenylsilatrane and 1-fluorosilatrane were formed in the molar ratio of 3:1. The structure of the synthesized compounds was proved by ¹H, ¹³C, ¹⁵N, ¹⁹F, ²⁹Si NMR and IR spectroscopy.

Russian Journal of General Chemistry published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C20H19NO4, Application In Synthesis of 312-40-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia