Catalysis-chemistry

Li, Xia published the artcileNovel 1-D double chain lanthanide complexes: Synthesis, structure and luminescence, Related Products of catalysis-chemistry, the publication is Inorganica Chimica Acta (2009), 362(8), 2837-2841, database is CAplus.

Treatment of Ln(NO₃)₃¡¤6H₂O with 1,2-phenylenedioxydiacetic acid (H₂PDOA) in ethanol leads to the unusual 1-dimensional double chain complexes {[Ln(PDOA)_1.5(H₂O)₃]¡¤H₂O}_n (Ln = Sm (1), Eu (2), Dy (3)), in which the Ln³⁺ ions are linked by pentadentate and bidentate PDOA ligands in two different directions. The chain looks like a ladder containing two -Ln-O-C-O-Ln- chains and PDOA spacers, which has never been observed in the lanthanide carboxylate complexes, and they exhibit different photoluminescence properties.

Inorganica Chimica Acta published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jiang, Yong published the artcileSupramolecular networks constructed from mono- and bi-nuclear lanthanide complexes with 1,2-phenylenedioxydiacetic acid, Recommanded Product: 2,2-(1,2-Phenylenebis(oxy))diacetic acid, the publication is Journal of Coordination Chemistry (2010), 63(1), 36-45, database is CAplus.

[Tb₂(1,2-pdoa)₃¡¤6H₂O]¡¤H₂O (1) and [La(1,2-pdoa)(1,2-H₂pdoa)(OH)¡¤H₂O]¡¤5H₂O (2) (1,2-H₂pdoa = 1,2-phenylenedioxydiacetic acid) were synthesized and structurally characterized by single crystal x-ray diffraction. Complex 1 is a binuclear mol. in which one 1,2-pdoa ligand is a tetradentate bridge linking two Tb³⁺ ions, the other two 1,2-pdoa ligands bond Tb1³⁺ and Tb1A³⁺ via tetradentate chelating coordination. Tb³⁺ is nine-coordinate by six oxygens of 1,2-pdoa and three waters. Complex 2 is mononuclear with La³⁺ ten-coordinate by eight oxygens of two 1,2-pdoa, one hydroxide and one water. 1,2-Pdoa is tetradentate chelating with La³⁺ ion. The packing diagrams of 1 and 2 show supramol. networks via H-bonds. The fluorescence spectrum of 1 shows characteristic emission of Tb³⁺ with ⁵D₄ ¡ú ⁷F_j (j = 6-3) transitions.

Journal of Coordination Chemistry published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Recommanded Product: 2,2-(1,2-Phenylenebis(oxy))diacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hu, Kuan published the artcileWhole-body PET tracking of a D-dodecapeptide and its radiotheranostic potential for PD-L1 overexpressing tumors, SDS of cas: 71989-31-6, the publication is Acta Pharmaceutica Sinica B (2022), 12(3), 1363-1376, database is CAplus and MEDLINE.

Peptides that are composed of dextrorotary (D)-amino acids have gained increasing attention as a potential therapeutic class. However, our understanding of the in vivo fate of D-peptides is limited. This highlights the need for whole-body, quant. tracking of D-peptides to better understand how they interact with the living body. Here, we used mouse models to track the movement of a programmed death-ligand 1 (PD-L1)-targeting D-dodecapeptide antagonist (DPA) using positron emission tomog. (PET). More specifically, we profiled the metabolic routes of [⁶⁴Cu]DPA and investigated the tumor engagement of [⁶⁴Cu/⁶⁸Ga]DPA in mouse models. Our results revealed that intact [⁶⁴Cu/⁶⁸Ga]DPA was primarily eliminated by the kidneys and had a notable accumulation in tumors. Moreover, a single dose of [⁶⁴Cu]DPA effectively delayed tumor growth and improved the survival of mice. Collectively, these results not only deepen our knowledge of the in vivo fate of D-peptides, but also underscore the utility of D-peptides as radiopharmaceuticals.

Acta Pharmaceutica Sinica B published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, SDS of cas: 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhou, Huajin published the artcileComparison of endogenous amino acid losses in broilers when offered nitrogen-free diets with differing ratios of dextrose to corn starch, Formula: C5H11NO2S, the publication is Scientific Reports (2022), 12(1), 5689, database is CAplus and MEDLINE.

The nitrogen-free diet (NFD) method is widely used to determine the ileal endogenous amino acids (IEAAs) losses in broiler chickens. Starch and dextrose are the main components of NFD, but the effects of their proportion in the NFD on the IEAAs and the digestive physiol. of broilers are still unclear. This preliminary study aims to explore the best proportion of glucose and corn starch in NFD to simulate the normal intestinal physiol. of broilers, which helps to improve the accuracy of IEAAs determination For this purpose, 28-day-old broiler chickens were allocated to five treatment groups for a 3-day trial, including a control group and four NFD groups. The ratios of dextrose to corn starch (D/CS) in the four NFD were 1.00, 0.60, 0.33, and 0.14, resp. Results noted that NFD significantly reduced serum IGF-1, albumin, and uric acid levels compared with the control (P < 0.05), except there was no difference between group D/CS 0.33 and the control for IGF-1. The increased Asp, Thr, Ser, Glu, Gly, Ala, Val, Ile, Leu, His, Tyr, Arg, and Pro contents of IEAAs were detected in broilers fed the NFD with a higher ratio of D/CS (1.00 and 0.60) compared to the lower ratio of D/CS (0.33 and 0.14). Moreover, ileal digestibility of dry matter and activity of digestive enzymes increased as the D/CS elevated (P < 0.001). Further investigation revealed that the number of ileal goblet cells and Mucin-2 expression were higher in the group with D/CS at 1.00 when compared with group D/CS 0.33 and the control (P < 0.05). Microbiota anal. showed that NFD reshaped the gut microbiota, characterized by decreased microbial diversity and lower abundance of Bacteroidetes, and increased Proteobacteria (P < 0.05). Our results indicate that a higher D/CS ratio (1.00 and 0.60) in NFD increases IEAAs by promoting digestive enzymes and mucin secretion. However, the excessive proportion of starch (D/CS = 0.14) in NFD was unsuitable for the chicken to digest. The chickens fed with NFD with the D/CS ratio at 0.33 were closer to the normal digestive physiol. state. Thus, the ratio of D/CS in NFD at 0.33 is more appropriate to detect IEAAs of broiler chickens.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C8H19NO, Formula: C5H11NO2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Li, Yueqing published the artcileSynthesis and anti-platelet aggregation assay of cinnamoyl-tyramine amide analogues, Application In Synthesis of 16909-09-4, the publication is Yingyong Huaxue (2018), 35(10), 1174-1183, database is CAplus.

In order to explore the influence of methoxy substitution in benzene ring, methylation of tyramine hydroxyl and cinnamoyl-tyramine amines, on anti-platelet aggregation activities analogs, cinnamoyl-tyramine amide analogs were synthesized via condensation and methylation with eight benzaldehyde derivatives as raw materials. The structures of synthesized compounds were characterized by NMR spectroscopy(NMR), mass spectrometry(MS) and single crystal diffraction. Based on variable-temperature NMR, rotational isomerization based on amide bond was studied for compounds 4a?4h. Their anti-platelet aggregation activities were tested in vitro and assayed by Born test. The results show that nine analogs are more active than podocarpamide. Specifically, compounds 2c, 4c and 4f show inhibition rates of 50.03%, 60.87% and 53.33%, resp., at 200 ¦Ìmol/L. The preliminary structure-activity relationship studies on these compounds indicate that 4-methoxy substituent is the most favorable for anti-ADP(adenosine-diphosphate) induced platelet aggregation, and methylated hydroxyl group on ring B and the amide nitrogen also increase the activities to some extent.

Yingyong Huaxue published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Application In Synthesis of 16909-09-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Cheng, Guilin published the artcileSynthesis of highly active enzyme-metal nanohybrids and uncovering the design rules, Formula: C3H6F3N, the publication is Enzyme and Microbial Technology (2022), 109962, database is CAplus and MEDLINE.

Nanobiohybrid CAL-B/MNPs were synthesized through enzyme in situ reduction of metal ions, including noble and non-noble metals. Lipase CAL-B acted as multifunctional reagents (reducing and supporting agents). The hybrid catalysts were systematically characterized by HRTEM, EDX, MALDI-TOF-MS, and XPS anal., confirming that highly dispersed 3-5 nm nanoparticles were evenly dispersed on lipase matrix without agglomeration. The mechanism of CAL-B reducing metal ions was investigated, revealing that AGLFFSSKDL in the amino acid sequence of CAL-B from 111 to 128 formed a stable spatial structure through hydrogen bonding, which was the key factor for enzyme in situ reduction of metal ions into highly dispersed nanoparticles.

Enzyme and Microbial Technology published new progress about 421-49-8. 421-49-8 belongs to catalysis-chemistry, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain, name is 1,1,1-Trifluoropropan-2-amine, and the molecular formula is C3H6F3N, Formula: C3H6F3N.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhong, Dayou published the artcileIron-Catalyzed Intramolecular C-H Amidation of N-Benzoyloxyureas, Application of 4-Nitrophenylacetic acid, the publication is Chinese Journal of Chemistry (2021), 39(4), 855-858, database is CAplus.

A redox-neutral Fe-catalyzed intramol. C-H amidation of N-benzoyloxyureas was described. This methodol. employed a simple iron complex in situ generated from Fe(OTf)₂ and bipyridine as the catalyst and N-benzoyloxyureas as the nitrene precursors without using exogenous oxidants. An array of cyclic ureas I [R¹ = Me, n-hexane, Bn, etc.; R² = Me, Ph, 2-naphthyl, etc.; R³ = H, Me] were synthesized via aliphatic C(sp³)-H amidation in excellent yields. In addition, this catalytic system was also amenable to aryl C(sp²)-H nitrene insertion to provide benzimidazolones II [R¹ = Me; R⁴ = H, MeO, t-Bu, C(O)OMe] in moderate yields.

Chinese Journal of Chemistry published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C19H17N3O, Application of 4-Nitrophenylacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zheng, Anqi published the artcileA binding-enhanced but enzymatic activity-eliminated human ACE2 efficiently neutralizes SARS-CoV-2 variants, SDS of cas: 63-68-3, the publication is Signal Transduction and Targeted Therapy (2022), 7(1), 10, database is CAplus and MEDLINE.

The goal is to generate a recombinant ACE2 protein that is long lasting without enzymic activity and can potently neutralize different SARS-CoV-2 variants. To screen efficient ACE2 fusion proteins with neutralization activity against both the wild-type SARS-CoV-2 strain (SARS-CoV-2 WT) and variants, we designed a panel of hACE2 proteins with mutations in the binding interface with the SARS-CoV-2 RBD. We focused on five potentially critical hydrophobic or charged residues, T27, D30, K31, H34, and M82, and designed seven mutants (T27F, D30E, K31R, H34F, H34W, M82F, and M82W) that enhance their hydrophobicity or electrification. We found that the binding affinities of two hACE2-mFc mutants, T27F and D30E, were enhanced, the affinities of two others, K31R and H34F, were diminished, and the affinities of the remaining three, H34W, M82F, and M82W, were nearly identical to that of wild-type hACE2 (hACE2-WT). HACE2-WT and mutant proteins can neutralize both SARS-CoV-2 WT and variants infection with decreased the half maximal inhibitory concentrations in Vero cells. Our binding and neutralization analyses indicate that hACE2-T27F-R273Q has potential as a broad antiviral therapeutic against current and future SARS-CoV-2 variants, and provides insights into its potential for the treatment of infections of other SARS-like coronavirus who use the ACE2 as entry receptor.

Signal Transduction and Targeted Therapy published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H5NO3S, SDS of cas: 63-68-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chen, Weibin published the artcileEthers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands, Application In Synthesis of 1860-58-8, the publication is Bioorganic & Medicinal Chemistry Letters (2005), 15(13), 3201-3202, database is CAplus and MEDLINE.

Gamma-hydroxybutyric acid (GHB) is a drug of abuse, a therapeutic, and purportedly a neurotransmitter with a complex mechanism of action in vivo due to direct actions at GABA_B as well as GHB receptors and because of its metabolism to GABA. Herein, the authors describe 3-ethers of 3-hydroxyphenylacetic acid, which have relatively high affinity at GHB sites, no significant affinity at GABA receptors, and would not be expected to be rapidly metabolized to GABAergic ligands. The selectivity of these compounds (UMB108, UMB109, and UMB119) could prove to be useful for studying the biol. of GHB receptors, free from GABAergic effects.

Bioorganic & Medicinal Chemistry Letters published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, Application In Synthesis of 1860-58-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Xu, Longhua published the artcileFlotation and adsorption of mixed cationic/anionic collectors on muscovite mica, Related Products of catalysis-chemistry, the publication is Minerals Engineering (2013), 41-45, database is CAplus.

The adsorption of dodecylamine acetate (DAA), sodium oleate (NaOL) and DAA-NaOL mixtures on muscovite mica were investigated through flotation tests, zeta potential measurements, and pyrene fluorescence tests. The results show that the muscovite mica has a neg. charge over the pH range 2-12. The muscovite mica did not float in the presence of NaOL alone. However, the recovery of muscovite mica ranged from ca. 80% (at pH 2) to 50% (at pH 11) using DDA alone. In the presence of mixed DAA-NaOL, recovery ranged from ca. 80% (at pH 2) to 90% (at pH 11). The individual cationic collectors DAA can be adsorbed strongly onto the muscovite mica, but no significant adsorption of anionic collectors NaOL can be detected by zeta potential measurements. In the mixed systems, the adsorption of both the cationic and anionic collectors are enhanced due to co-adsorption. The presence of NaOL in the mixture decreases the electrostatic head-head repulsion between the surface and ammonium ions and increases the lateral tail-tail hydrophobic bonds. Mol. dynamics (MD) simulations were conducted to further investigate the adsorption of DDA, NaOL, and DAA-NaOL on the (0 0 1) basal planes of muscovite using Materials Studio 5.0 program. The conclusions drawn from theor. computations are in good agreement with exptl. results.

Minerals Engineering published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C17H20ClN3, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia