Catalysis-chemistry

Liu, Xuesong published the artcileSilver-Catalyzed Decarboxylative Alkynylation of Aliphatic Carboxylic Acids in Aqueous Solution, Name: 2-Methyl-4-phenylbutanoic acid, the publication is Journal of the American Chemical Society (2012), 134(35), 14330-14333, database is CAplus and MEDLINE.

C(sp³)-C(sp) bond formations are of immense interest in chem. and material sciences. We report herein a convenient, radical-mediated and catalytic method for C(sp³)-C(sp) cross-coupling. Thus, with AgNO₃ as the catalyst and K₂S₂O₈ as the oxidant, various aliphatic carboxylic acids underwent decarboxylative alkynylation with com. available ethynylbenziodoxolones in aqueous solution under mild conditions. This site-specific alkynylation is not only general and efficient but also functional group compatible. In addition, it exhibits remarkable chemo- and stereoselectivity.

Journal of the American Chemical Society published new progress about 1949-41-3. 1949-41-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene, name is 2-Methyl-4-phenylbutanoic acid, and the molecular formula is C11H14O2, Name: 2-Methyl-4-phenylbutanoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ren, Xinyi published the artcileAsymmetric Alkoxy- and Hydroxy-Carbonylations of Functionalized Alkenes Assisted by ¦Â-Carbonyl Groups, Category: catalysis-chemistry, the publication is Angewandte Chemie, International Edition (2021), 60(32), 17693-17700, database is CAplus and MEDLINE.

As a fundamental type of carbonylation reaction, the alkoxy- and hydroxy-carbonylation of unsaturated hydrocarbons constitutes one of the most important industrial applications of homogeneous catalysis. However, owing to the difficulties in controlling multi-selectivities for asym. hydrocarbonylation of alkenes, this reaction is typically limited to vinylarenes and analogs. In this work, a highly efficient asym. alkoxy- and hydroxy-carbonylation of ¦Â-carbonyl functionalized alkenes was developed, providing practical and easy access to various densely functionalized chiral mols. with high optical purity from broadly available alkenes, CO, and nucleophiles (>90 examples, 84-99% ee). This protocol features mild reaction conditions and a broad substrate scope, and the products can be readily transformed into a diverse array of chiral heterocycles. Control experiments revealed the key role of the ¦Â-carbonyl group in determining the enantioselectivity and promoting the activity, which facilitates chiral induction by coordination to the transition metal as rationalized by DFT calculations The strategy of utilizing an innate functional group as the directing group on the alkene substrate might find further applications in catalytic asym. hydrocarbonylation reactions.

Angewandte Chemie, International Edition published new progress about 15732-75-9. 15732-75-9 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ketone, name is 2-Methylene-4-oxo-4-phenylbutanoic acid, and the molecular formula is C11H10O3, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sun, Weiwei published the artcileElectro-optic thin films of organic nonlinear optic molecules aligned through vacuum deposition, COA of Formula: C14H14N2O2, the publication is Optics Express (2011), 19(12), 11189-11195, database is CAplus and MEDLINE.

Nonlinear optical mols. can be vacuum deposited into uniform thin films using thermal evaporation Alignment order can be achieved during thin film deposition by an in-plane elec. field poling using electrodes patterned on the substrate. Electro-optic (EO) coefficients, r₃₃ and r₁₃ are independently measured using Young’s interferometry technique. Thin-films of N-benzyl-2-methyl-4-nitroaniline (BNA) can exhibit an EO coefficient, r₃₃, comparable to that of BNA single crystals. EO coefficients of BNA at different poling fields, wavelengths, and frequencies are investigated.

Optics Express published new progress about 201157-13-3. 201157-13-3 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is N-Benzyl-2-methyl-4-nitroaniline, and the molecular formula is C12H10F2Si, COA of Formula: C14H14N2O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lei, Yali published the artcileCharacteristics and health risks of parent, alkylated, and oxygenated PAHs and their contributions to reactive oxygen species from PM_2.5 vehicular emissions in the longest tunnel in downtown Xi¡äan, China, Related Products of catalysis-chemistry, the publication is Environmental Research (2022), 212(Part_C), 113357, database is CAplus and MEDLINE.

A vehicular emission study was conducted in the longest inner-city tunnel in Xi¡äan, northwestern China in four time periods (I: 07:30-10:30, II: 11:00-14:00, III: 16:30-19:30, and IV: 20:00-23:00 LST). A sum of 40 PAHs, including parent (p-PAHs), alkylated (a-PAHs), and oxygenated (o-PAHs) in fine particulate matter (PM_2.5) were quantified. The relationships between the PAHs and the formation of reactive oxygen species (ROS) were also studied. The average total quantified PAHs concentration was 236.3 ¡À 48.3 ng m^-3. The p-PAHs were found to be the most dominated group, accounting for an average of 88.1% of the total quantified PAHs, followed by a-PAHs (6.1%) and o-PAHs (5.8%). On the base of the number of aromatic rings, the groups of ¡Ü5 rings (92.5 ¡À 1.2%) had higher fractions than the high ones (¡Ý6 rings, 7.5 ¡À 1.2%) for pPAHs. Diurnal variations of PAHs subgroups exhibited the highest levels in Period III, consistent with the largest traffic counts in evening rush hours. However, less reduction of few PAHs in the night period demonstrates that the emissions of compressed natural gas (CNG) and methanol-fueled vehicles cannot be ignored while their contribution increased. High ROS activity levels were observed in the traffic-dominated samples, implying the potential oxidative damages to humans. Addnl., diurnal variation of the ROS activity was consistent with the total quantified PAHs and toxic equivalency of benzo[a]pyrene. Good correlations (R > 0.6, p < 0.05) were seen between individual groups of PAHs (especially for 3-5 rings p-PAHs, 4 rings a-PAHs, and 2-3 rings o-PAHs) and ROS activity, supporting that the vehicular emitted PAHs possibly initiate oxidative stress. The multiple linear regression anal. further illustrated that chrysene contributed the highest (25.0%) to ROS activity. In addition to highlighting the potential hazards to the PAHs from the vehicular emission, their roles to mitigate the health effects by formations of ROS were firstly reported in northwestern China.

Environmental Research published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ma, Qiuyue published the artcileAssembly and comparative analysis of the first complete mitochondrial genome of Acer truncatum Bunge: a woody oil-tree species producing nervonic acid, Product Details of C5H11NO2S, the publication is BMC Plant Biology (2022), 22(1), 29, database is CAplus and MEDLINE.

Acer truncatum (purpleblow maple) is a woody tree species that produces seeds with high levels of valuable fatty acids (especially nervonic acid). The species is admired as a landscape plant with high developmental prospects and scientific research value. The A. truncatum chloroplast genome has recently been reported; however, the mitochondrial genome (mitogenome) is still unexplored. We characterized the A. truncatum mitogenome, which was assembled using reads from PacBio and Illumina sequencing platforms, performed a comparative anal. against different species of Acer. The circular mitogenome of A. truncatum has a length of 791,052 bp, with a base composition of 27.11% A, 27.21% T, 22.79% G, and 22.89% C. The A. truncatum mitogenome contains 62 genes, including 35 protein-coding genes, 23 tRNA genes and 4 rRNA genes. We also examined codon usage, sequence repeats, RNA editing and selective pressure in the A. truncatum mitogenome. To determine the evolutionary and taxonomic status of A. truncatum, we conducted a phylogenetic anal. based on the mitogenomes of A. truncatum and 25 other taxa. In addition, the gene migration from chloroplast and nuclear genomes to the mitogenome were analyzed. Finally, we developed a novel NAD1 intron indel marker for distinguishing several Acer species. In this study, we assembled and annotated the mitogenome of A. truncatum, a woody oil-tree species producing nervonic acid. The results of our analyses provide comprehensive information on the A. truncatum mitogenome, which would facilitate evolutionary research and mol. barcoding in Acer.

BMC Plant Biology published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Product Details of C5H11NO2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Shuai published the artcileLipase immobilization on multi-walled carbon nanotubes used as a target fishing tool and followed by molecular docking technique to analyze lipase inhibitor from Robinia pseudoacacia L., Synthetic Route of 13822-56-5, the publication is Industrial Crops and Products (2022), 114645, database is CAplus.

In this study, R. pseudoacacia flowers exhibited potential lipase (Aspergillus niger) inhibitory activity. To quickly explore the active compound, ligand fishing was adopted for screening the ligand from R. pseudoacacia flowers by lipase immobilized on magnetic polyamidoamine dendrimer-coated multi-walled carbon nanotubes. After ligand fishing, the target compound was separated purposefully by optimizing the separation conditions of high-speed counter-current chromatog. (HSCCC). As results, kaempferol with the IC50 of 327.64 ¡À 15.33¦Ìg/mL was separated and identified. The further mol. docking results indicated that kaempferol was interacted with amino acid residue in the active site of lipase through van der Waals force, hydrogen bonds and Pi-Pi T-shaped interactions, yielding the binding energy of – 6.43 kcal/mol. The present method not only revealed the lipase inhibitory substances in R. pseudoacacia, but also provided an effective means for the screening of other natural substances.

Industrial Crops and Products published new progress about 13822-56-5. 13822-56-5 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is 3-(Trimethoxysilyl)propan-1-amine, and the molecular formula is C10H9NO4S, Synthetic Route of 13822-56-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sun, Wei published the artcileNature of (001) and (00^–1) faces and flocculation flotation of kaolinite, COA of Formula: C14H31NO2, the publication is Transactions of Nonferrous Metals Society of China (2003), 13(4), 968-971, database is CAplus.

Flotation mechanism of kaolinite was investigated through flotation test, SEM anal., and quantum chem. simulation calculation The (001) face of kaolinite easily adsorb cationic collector to exhibit hydrophobicity; the (00^–1) face is easily interacted with the reagent carrying the group of high electronegativity (-O-, -N-, F-) to show hydrophilicity. The cationic and anionic polyacrylamide are adsorbed onto the (00^–1) face of kaolinite and the flocculation of kaolinite particles may take place; the (001) faces are exposed to interact with cationic collector to be rendered hydrophobicity. Thus, the macromols. can evidently enhance the flotation of kaolinite in alk. media.

Transactions of Nonferrous Metals Society of China published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C15H24O2, COA of Formula: C14H31NO2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hua, Ying-peng published the artcileCombined morpho-physiological, ionomic and transcriptomic analyses reveal adaptive responses of allohexaploid wheat (Triticum aestivum L.) to iron deficiency, Recommanded Product: (S)-2-Amino-4-(methylthio)butanoic acid, the publication is BMC Plant Biology (2022), 22(1), 234, database is CAplus and MEDLINE.

Plants worldwide are often stressed by low Fe availability around the world, especially in aerobic soils. Therefore, the plant growth, seed yield, and quality of crop species are severely inhibited under Fe deficiency. Fe metabolism in plants is controlled by a series of complex transport, storage, and regulatory mechanisms in cells. Allohexaploid wheat (Triticum aestivum L.) is a staple upland crop species that is highly sensitive to low Fe stresses. Although some studies have been previously conducted on the responses of wheat plants to Fe deficiency, the key mechanisms underlying adaptive responses are still unclear in wheat due to its large and complex genome. Transmission electron microscopy showed that the chloroplast structure was severely damaged under Fe deficiency. Paraffin sectioning revealed that the division rates of meristematic cells were reduced, and the sizes of elongated cells were diminished. ICP-MS-assisted ionmics anal. showed that low-Fe stress significantly limited the absorption of nutrients, including N, P, K, Ca, Mg, Fe, Mn, Cu, Zn, and B nutrients. High-throughput transcriptome sequencing identified 378 and 2,619 genome-wide differentially expressed genes (DEGs) were identified in the shoots and roots between high-Fe and low-Fe conditions, resp. These DEGs were mainly involved in the Fe chelator biosynthesis, ion transport, photosynthesis, amino acid metabolism, and protein synthesis. Gene coexpression network diagrams indicated that TaIRT1b-4A, TaNAS2-6D, TaNAS1a-6A, TaNAS1-6B, and TaNAAT1b-1D might function as key regulators in the adaptive responses of wheat plants to Fe deficiency. These results might help us fully understand the morpho-physiol. and mol. responses of wheat plants to low-Fe stress, and provide elite genetic resources for the genetic modification of efficient Fe use.

BMC Plant Biology published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Recommanded Product: (S)-2-Amino-4-(methylthio)butanoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wu, Huang published the artcileA contorted nanographene shelter, HPLC of Formula: 191-07-1, the publication is Nature Communications (2021), 12(1), 5191, database is CAplus and MEDLINE.

Abstract: Nanographenes have kindled considerable interest in the fields of materials science and supramol. chem. as a result of their unique self-assembling and optoelectronic properties. Encapsulating the contorted nanographenes inside artificial receptors, however, remains challenging. Herein, we report the design and synthesis of a trigonal prismatic hexacationic cage, which has a large cavity and adopts a relatively flexible conformation. It serves as a receptor, not only for planar coronene, but also for contorted nanographene derivatives with diameters of approx. 15 ? and thicknesses of 7 ?. A comprehensive investigation of the host-guest interactions in the solid, solution and gaseous states by experimentation and theor. calculations reveals collectively an induced-fit binding mechanism with high binding affinities between the cage and the nanographenes. Notably, the photostability of the nanographenes is improved significantly by the ultrafast deactivation of their excited states within the cage. Encapsulating the contorted nanographenes inside the cage provides a noncovalent strategy for regulating their photoreactivity.

Nature Communications published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C18H26ClN3O, HPLC of Formula: 191-07-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Liu, Xingui published the artcileSenolytic activity of piperlongumine analogues: Synthesis and biological evaluation, COA of Formula: C11H12O4, the publication is Bioorganic & Medicinal Chemistry (2018), 26(14), 3925-3938, database is CAplus and MEDLINE.

Selective clearance of senescent cells (SCs) has emerged as a potential therapeutic approach for age-related diseases, as well as chemotherapy- and radiotherapy-induced adverse effects. Through a cell-based phenotypic screening approach, we recently identified piperlongumine (PL), a dietary natural product, as a novel senolytic agent, referring to small mols. that can selectively kill SCs over normal or non-senescent cells. In an effort to establish the structure-senolytic activity relationships of PL analogs, we performed a series of structural modifications on the trimethoxyphenyl and the ¦Á,¦Â-unsaturated ¦Ä-valerolactam rings of PL. We show that modifications on the trimethoxyphenyl ring are well tolerated, while the Michael acceptor on the lactam ring is critical for the senolytic activity. Replacing the endocyclic C2-C3 olefin with an exocyclic methylene at C2 render PL analogs 47-49 with increased senolytic activity. These ¦Á-methylene containing analogs are also more potent than PL in inducing ROS production in WI-38 SCs. Similar to PL, 47-49 reduce the protein levels of oxidation resistance 1 (OXR1), an important oxidative stress response protein that regulates the expression of a variety of antioxidant enzymes, in cells. This study represents a useful starting point toward the discovery of senolytic agents for therapeutic uses.

Bioorganic & Medicinal Chemistry published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, COA of Formula: C11H12O4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia