Catalysis-chemistry

Guercio, Angelica M. published the artcileStructural and functional analyses explain Pea KAI2 receptor diversity and reveal stereoselective catalysis during signal perception, Computed Properties of 63-68-3, the publication is Communications Biology (2022), 5(1), 126, database is CAplus and MEDLINE.

KAI2 proteins are plant ¦Á/¦Â hydrolase receptors which perceive smoke-derived butenolide signals and endogenous, yet unidentified KAI2-ligands (KLs). The number of functional KAI2 receptors varies among species and KAI2 gene duplication and sub-functionalization likely plays an adaptative role by altering specificity towards different KLs. Legumes represent one of the largest families of flowering plants and contain many agronomic crops. Prior to their diversification, KAI2 underwent duplication resulting in KAI2A and KAI2B. Here we demonstrate that Pisum sativum KAI2A and KAI2B are active receptors and enzymes with divergent ligand stereoselectivity. KAI2B has a higher affinity for and hydrolyzes a broader range of substrates including strigolactone-like stereoisomers. We determine the crystal structures of PsKAI2B in apo and butenolide-bound states. The biochem., structural, and mass spectra analyses of KAI2s reveal a transient intermediate on the catalytic serine and a stable adduct on the catalytic histidine, confirming its role as a bona fide enzyme. Our work uncovers the stereoselectivity of ligand perception and catalysis by diverged KAI2 receptors and proposes adaptive sensitivity to KAR/KL and strigolactones by KAI2B.

Communications Biology published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Computed Properties of 63-68-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Stoll, Emma L. published the artcileA practical catalytic reductive amination of carboxylic acids, Safety of 2-(2-((tert-Butyldimethylsilyl)oxy)ethoxy)ethan-1-amine, the publication is Chemical Science (2020), 11(35), 9494-9500, database is CAplus and MEDLINE.

Reductive alkylation reactions of amines using carboxylic acids as nominal electrophiles was reported. The two-step reaction exploits the dual reactivity of phenylsilane and involves a silane-mediated amidation followed by a Zn(OAc)₂-catalyzed amide reduction The reaction is applicable to a wide range of amines and carboxylic acids and has been demonstrated on a large scale (305 mmol of amine). The rate differential between the reduction of tertiary and secondary amide intermediates is exemplified in a convergent synthesis of the antiretroviral medicine maraviroc. Mechanistic studies demonstrate that a residual 0.5 equiv of carboxylic acid from the amidation step is responsible for the generation of silane reductants with augmented reactivity, which allow secondary amides, previously unreactive in zinc/phenylsilane systems, to be reduced.

Chemical Science published new progress about 215297-17-9. 215297-17-9 belongs to catalysis-chemistry, auxiliary class Linker,PROTAC Linker, name is 2-(2-((tert-Butyldimethylsilyl)oxy)ethoxy)ethan-1-amine, and the molecular formula is C8H15BrO2, Safety of 2-(2-((tert-Butyldimethylsilyl)oxy)ethoxy)ethan-1-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jiang, Senhao published the artcileComparison of biochemical composition of commercial sea cucumbers, Apostichopus japonicus and Parastichopus californicus, under the same culture conditions, Safety of Docosahexaenoic Acid, the publication is Journal of the Science of Food and Agriculture (2022), 102(12), 5452-5459, database is CAplus and MEDLINE.

Apostichopus japonicus and Parastichopus californicus are two of the most important and profitable com. sea cucumbers along the North Pacific coast. This study compared the body wall production rate (BWPR), proximate composition, amino acid, fatty acid, trace element and vitamin composition, and nonspecific immune enzyme activities of A. japonicus and P. californicus cultured in an artificial pond. The BWPR, crude fat and ash content in the body walls of A. japonicus and P. californicus showed remarkable differences (P < 0.05). For the 18 amino acids tested, differences in the contents of 15 were significant (P < 0.05) between the two species, except for threonine, methionine and histidine, and their first limiting amino acids were both methionine+cysteine. There were seven saturated and ten unsaturated fatty acids in their body walls, and except for 18:1 and 20:1, the content differences of the other 15 fatty acids were all significant (P < 0.05). Furthermore, between the two sea cucumbers, differences in the content of seven trace elements (Cu, Fe, Mn, Zn, Cr, Ni, Se) and six vitamins (B1, B3, B5, B9, C, E) were significant (P < 0.05). The activities of superoxide dismutase (SOD), catalase (CAT), acid phosphatase (ACP) and alk. phosphatase (AKP) also showed distinct differences (P < 0.05). There are greater differences in the biochem. compositions and contents between A. japonicus and P. californicus, each with its own unique quality advantages. A. japonicus and P. californicus have high nutritional value, which are both the superior sea cucumbers. 2022 Society of Chem. Industry.

Journal of the Science of Food and Agriculture published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Safety of Docosahexaenoic Acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hu, Zhiyong published the artcileRhodium(III)-Catalyzed Cascade Cyclization/Electrophilic Amidation for the Synthesis of 3-Amidoindoles and 3-Amidofurans, Formula: C6H12F3NO5S, the publication is Organic Letters (2016), 18(9), 2058-2061, database is CAplus and MEDLINE.

A rhodium(III)-catalyzed cascade cyclization/electrophilic amidation of N-tosyl-2-alkynylanilines and 2-alkynylphenols I [R = H, 4-Cl, 4-F, 4-O₂N, 4-F₃C, 4-EtO₂C, 4-Me, 5-Me (locants with respect to aniline or phenol functional group); R¹ = Bu, TBDMSOCH₂, Ph, 4-MeC₆H₄, 4-MeOC₆H₄, 4-FC₆H₄, 4-BrC₆H₄; X = TsN, O; TBDMS = tert-butyldimethylsilyl] with N-pivaloyloxylamides R²CONHOCOt-Bu [R² = PhCH₂, 4-MeC₆H₄CH₂, 3-ClC₆H₄CH₂, 3-BrC₆H₄CH₂, 2-IC₆H₄CH₂, ClCH₂, H₂C:CH, Me₂C:CH, (E)-PhCH:CH] as the electrophilic nitrogen source to yield 3-amidoindoles and 3-amidofurans II [R = H, 4-Cl, 4-F, 4-O₂N, 4-F₃C, 4-EtO₂C, 4-Me, 5-Me; R¹ = Bu, TBDMSOCH₂, Ph, 4-MeC₆H₄, 4-MeOC₆H₄, 4-FC₆H₄, 4-BrC₆H₄; R² = PhCH₂, 4-MeC₆H₄CH₂, 3-ClC₆H₄CH₂, 3-BrC₆H₄CH₂, 2-IC₆H₄CH₂, ClCH₂, H₂C:CH, Me₂C:CH, (E)-PhCH:CH; X = TsN, O] under mild conditions with good functional group tolerance has been developed. The synthetic utility of this reaction has been demonstrated through the derivatization of selected 3-amidoindoles to several heterocycle-fused indoles. The structure of II (R = H; R¹ = 4-BrC₆H₄; R² = PhCH₂) was determined by X-ray crystallog.

Organic Letters published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Formula: C6H12F3NO5S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Du, Yuan-Hang published the artcileDevelopment of a kinetics-integrated CFD model for the industrial scale-up of DHA fermentation using Schizochytrium sp., Formula: C22H32O2, the publication is AIChE Journal (2022), 68(9), e17750, database is CAplus.

In this work, a kinetics-integrated CFD model based on coupling computational fluid dynamics (CFD) and biokinetic was developed to guide the industrial scale-up for fermentation of docosahexaenoic acid (DHA). Two-substrate biokinetic equations for a 5 L bioreactor with oxygen and nitrogen source as limiting substrates were established, which were further coupled with CFD to simulate the biomass growth and lipid accumulation as well as flow field environment in the fermentation process. The coupled CFD-biokinetic model can accurately reflect the changes of each relevant variable in the 50 L bioreactor under different operating conditions. The optimal working conditions of a 35 m³ bioreactor were predicted by this model and have secured the one-step scale-up of DHA fermentation, resulting in a biomass, lipid concentration, and DHA content in lipids of 99.2 g/L, 55.7 g/L, and 52.5%, resp. This study thus provides an effective strategy for rapid industrial scale-up of DHA production

AIChE Journal published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Formula: C22H32O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yano, Masafumi published the artcileCalix[4]pyrrole-based anion transporters with tuneable transport properties, Computed Properties of 17351-61-0, the publication is Organic & Biomolecular Chemistry (2010), 8(19), 4356-4363, database is CAplus and MEDLINE.

Three new bis-1,2,3-triazole strapped calix[4]pyrroles have been prepared via click’ chem. and their anion complexation and lipid bilayer transport properties studied by a combination of single crystal X-ray diffraction studies, ¹H NMR titration techniques, isothermal titration calorimetry and lipid bilayer anion transport studies in POPC vesicles. Bilayer transport efficiency for transmembrane chloride transport was found to directly depend on the length of the alkyl chain present in the bis-triazole strap.

Organic & Biomolecular Chemistry published new progress about 17351-61-0. 17351-61-0 belongs to catalysis-chemistry, auxiliary class Phase Transfer Catalyst, name is Tetraethylammonium hydrogencarbonate, and the molecular formula is C18H14BrNO5S2, Computed Properties of 17351-61-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Inoue, Toshio published the artcileA study on the treatment of metallurgical wastes containing heavy metals. III. Flotation of lead sulfate in the red residue of a hydrometallurgical zinc smelter, Computed Properties of 2016-56-0, the publication is Sogo Shikensho Nenpo (Tokyo Daigaku Kogakubu) (1981), 159-64, database is CAplus.

The leaching red residue from a Zn smelter contains 6-10% Pb as Pb-SO₄. Zn ions are removed by washing and residual flocculant is removed by attrition grinding. The flotation pulp is heated to 35-45¡ã and treated with C_12-16 amine acetate and Na hexadecyl sulfate. Flotation with combined depressants, starch, and gum arabic and 3-stage cleaning gives a concentrate containing 39-42 % Pb for a recovery of 68-70%.

Sogo Shikensho Nenpo (Tokyo Daigaku Kogakubu) published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Computed Properties of 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Inoue, Toshio published the artcileTreatment of metallurgical wastes containing heavy metals. II. Separation of lead sulfate and ferric oxide with dodecylamine acetate. With special reference to the effect of starch and arabic gum as a ferric oxide depressor, Quality Control of 2016-56-0, the publication is Sogo Shikensho Nenpo (Tokyo Daigaku Kogakubu) (1980), 191-7, database is CAplus.

PbSO₄ and Fe₂O₃ were flotated from a solution containing no metal ions by dodecylamine acetate [2016-56-0] in the pH range 0-11 and 2-8, resp. When the same floatation tests were conducted in the solution containing 50 g ZnSO₄/L, the flotation of PbSO₄ was decreased to pH <3. Starch was the most effective depressor for separation of PbSO₄ and Fe₂O₃ by flotation at pH 2.7. The Pb recovery was 90.9%.

Sogo Shikensho Nenpo (Tokyo Daigaku Kogakubu) published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Quality Control of 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Borjian, Sogol published the artcilePd(¦Ç³-1-PhC₃H₄)(¦Ç⁵-C₅H₅) as a Catalyst Precursor for Buchwald-Hartwig Amination Reactions, COA of Formula: C30H42NOP, the publication is Organometallics (2014), 33(15), 3928-3935, database is CAplus.

The compound Pd(¦Ç³-1-Ph-C₃H₄)(¦Ç⁵-C₅H₅) (I) reacts cleanly with many tertiary phosphines L to undergo reductive elimination of PhC₃H₄-C₅H₅ and form palladium(0) species of the types PdL_n (n = 2, 3), long believed to be exemplary catalysts for Suzuki-Miyaura, Heck-Mizoroki, and Sonogashira cross-coupling reactions. I has accordingly been generally much more effective for these catalytic processes than are conventional catalyst precursors such as Pd(PPh₃)₄, Pd₂(dba)₃, PdCl₂, and Pd(OAc)₂, in large part because I stands alone in this series for its ability to generate specifically and efficiently the desired species PdL₂ in many cases. Authors have now investigated I as a precursor for prototypical Buchwald-Hartwig amination reactions of 4-bromo- and 4-chloroanisole with morpholine, making comparisons with Pd₂(dba)₃, Pd(OAc)₂, and [Pd(¦Ç³-1-Ph-C₃H₄)Cl]₂ (IV). In this work authors have utilized PBu^t₃ because of its general effectiveness, and have also assessed XPhos and Mor-Dalphos, representatives of important classes of phosphines utilized elsewhere for amination reactions.

Organometallics published new progress about 1237588-12-3. 1237588-12-3 belongs to catalysis-chemistry, auxiliary class Mono-phosphine Ligands, name is 4-(2-(Di(adamantan-1-yl)phosphino)phenyl)morpholine, and the molecular formula is C30H42NOP, COA of Formula: C30H42NOP.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Cook, A. Gilbert published the artcileThe blue bottle experiment revisited. How Blue? How Sweet?, Computed Properties of 10510-54-0, the publication is Journal of Chemical Education (1994), 71(2), 160-1, database is CAplus.

The “Blue Bottle” experiment was first popularized by Campbell. The reaction consists of a flask about half full of a colorless liquid that, when shaken, turns blue. When left to stand the liquid turns colorless again. The cyclic process – being shaken, turning blue, being left to stand, and turning colorless – can be repeated many times. By making a series of guided observations with this simple but colorful system, the student can determine a rate law and a plausible mechanism for the reaction without ever knowing the contents of the flask. The activation energy of the reaction can also be measured by making observations at various temperatures This popular experiment has been carried out by general chem. students at Valparaiso University since 1963 with great success.

Journal of Chemical Education published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C18H15N3O3, Computed Properties of 10510-54-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia