Tag: M.W=100-150

Morrelli, Derek published the artcileRole of solvent dielectric constant on the enthalpy-entropy compensation in the hindered amide bond rotation, Product Details of C8H8O2, the publication is Chemical Physics Letters (2022), 139412, database is CAplus.

Dynamic NMR (DNMR) experiments are performed on a series of analogs derived from N, N-diethyl-m-toluamide (DEET) in six different solvents of varying dielec. constant from toluene-d₈ (¦Å = 2.38) to DMSO-d₆ (¦Å = 46.7). The thermodn. parameters of the restricted rotation to the solvent dielec. constant do not have a straightforward correlation relationship between them. However, the activation enthalpy and entropy of more than sixty different exptl. measurements indicate that enthalpy-entropy compensation (EEC) was independent of the solvent condition with a compensation temperature of 287.81 ¡À 3.95 K. The results, therefore, support the broader role of EEC on the partial amide bond dynamics in the DEET analogs over the temperature range studied.

Chemical Physics Letters published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, Product Details of C8H8O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Utinans, M. published the artcileSynthesis and properties of 5-(5-amino-3,6-dichloro-1,4-benzoquinon-2-yl)-2-(dimethylamino)thiazoles, COA of Formula: C3H8N2S, the publication is Khimiya Geterotsiklicheskikh Soedinenii (1991), 410-15, database is CAplus.

The reaction of (trichlorobenzoquinonyl)triazole I (R = Cl) with secondary amines gave the corresponding 5-amino derivatives I [R = dialkylamino (II)]. The reduction and redox potentials of some II were studied.

Khimiya Geterotsiklicheskikh Soedinenii published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C28H41N2P, COA of Formula: C3H8N2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhou, Xiao published the artcileNickel-Catalyzed Reductive Acylation of Carboxylic Acids with Alkyl Halides and N-Hydroxyphthalimide Esters Enabled by Electrochemical Process, Product Details of C8H8O2, the publication is Advanced Synthesis & Catalysis (2022), 364(9), 1526-1531, database is CAplus.

A sustainable Ni-catalyzed reductive acylation reaction of carboxylic acids via an electrochem. pathway was presented, affording a ketones ArC(O)R [Ar = Ph, 4-MeC₆H₄, 4-PhC₆H₄, etc.; R = n-Bu, CH(Me)₂, CH₂Cy, etc.] as major products. The reaction proceeded at ambient temperature using unactivated alkyl halides and N-hydroxyphthalimide (NHP) esters as coupling partners, which exhibited several synthetic advantages, including mild conditions and convenience of amplification (58% yield for 6 mmol scale reaction).

Advanced Synthesis & Catalysis published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C6H8O6, Product Details of C8H8O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Hong-Xia published the artcileSynthesis of Acyl Hydrazides via a Radical Chemistry of Azocarboxylic tert-Butyl Esters, Product Details of C8H8O2, the publication is Journal of Organic Chemistry (2022), 87(10), 6573-6587, database is CAplus and MEDLINE.

A new chem. of azo compounds, i.e., addition of free radicals generated in situ to access various acyl hydrazides, has been developed. The protocol provides a novel strategy for the synthesis of valuable acyl hydrazides. The transformation features mild reaction conditions, good tolerance of functional groups, and a broad substrate scope. In view of the importance of acyl hydrazides in functional materials and medicinal chem., this approach would find broad applications.

Journal of Organic Chemistry published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C6H13NO2, Product Details of C8H8O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Che, Zhiping published the artcileSynthesis of paeonol ester derivatives and their insecticidal, nematicidal, and anti-oomycete activities, HPLC of Formula: 118-90-1, the publication is Pest Management Science (2022), 78(8), 3442-3455, database is CAplus and MEDLINE.

Paeonol is extracted and isolated as a rich and sustainable natural bioresource from the root bark of Paeonia suffruticosa, the derivatives of which exhibit numerous biol. activities. It is well known that ester compounds play a very important role in pest control, such as organophosphorus, carbamate and pyrethroid pesticides. To discover biorational natural product-based pesticides, three series of (60) paeonol ester derivatives (7a-t, 8g,p, 9g,p, 10g-j,n-u, 11g,u, 12g,u, 13a-p, 14b,c, and 15b,c) were prepared by structural modification of paeonol, and their structures were well characterized by proton NMR (¹H-NMR), carbon-13 NMR (¹³C-NMR), high-resolution mass spectrometry (HRMS), and m.p. Furthermore, we assessed the compounds as insecticidal, nematicidal, and anti-oomycete agents against three serious agricultural pests, Mythimna separata, Heterodera glycines, and Phytophthora capsici. Among all tested compounds: (i) compound 8p showed more significant insecticidal activity than toosendanin, and the final mortality rates of 8p and toosendanin against M. separata (1 mg mL^-1) were 70.4%, and 51.9%, resp.; (ii) compound 7a exhibited more promising nematicidal activity than paeonol, and the median lethal concentration (LC₅₀) values of 7a and 1 against H. glycines were 15.47 and 50.80 mg L^-1, resp.; (iii) compounds 7n and 13m displayed more significant anti-oomycete activity compared to zoxamide against Phytophthora capsici, and the median effective concentration (EC₅₀) values of 7n, 13m, and zoxamide were 23.72, 24.51, and 26.87 mg L^-1, resp.; and the protective effect of the compounds against Phytophthora capsici in vivo further confirmed the effectiveness of the agents. This study suggested that the introduction of a nitro at the C5 or C3 position of paeonol could improve its bioactivity against M. separata, H. glycines, and Phytophthora capsici.

Pest Management Science published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, HPLC of Formula: 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ahmed, Riyaz published the artcileTCT-mediated click chemistry for the synthesis of nitrogen-containing functionalities: conversion of carboxylic acids to carbamides, carbamates, carbamothioates, amides and amines, SDS of cas: 118-90-1, the publication is Organic & Biomolecular Chemistry (2022), 20(24), 4942-4948, database is CAplus and MEDLINE.

Reported a s-trichlorotriazine (TCT, also known as cyanuric chloride) mediated one-pot general method for the conversion of carboxylic acids into ubiquitous functionalities such as carbamides, carbamates, carbamothioates, amides and amines. The TCT-mediated activation of acids followed by azidation and heating led to the isocyanate formation via Curtius rearrangement which involved click chem. in the presence of nucleophiles and provided the coupled product. The TCT were employed at ¡Ü40 mol% with respect to the starting materials; however, its bulk availability and low cost provide a unique opportunity towards its applicability in the synthesis of functional mols. The optimized conditions was successfully demonstrated for gram scale synthesis and late-stage functionalization of natural products and drugs such as podophyllotoxin, eugenol, diosgenin, geraniol and fluvoxamine.

Organic & Biomolecular Chemistry published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, SDS of cas: 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tomazin, Ursa published the artcileCombinatorial Synthesis of Acacen-Type Ligands and Their Coordination Compounds, Application In Synthesis of 10517-44-9, the publication is ACS Combinatorial Science (2017), 19(6), 386-396, database is CAplus and MEDLINE.

A highly modular synthetic method for the preparation of acacen-type ligands and their coordination compounds was developed. 46 Acacen-type ligands were synthesized by a combinatorial acid-catalyzed transamination between six primary diamines and eight enaminones. The bis-enaminone products were used as tetradentate ligands for coordination of copper(II), nickel(II), cobalt(II), and palladium(II). Dependence of the preferred E- or Z-configuration of the enaminone ligand on the ¦Á-substituent of the enaminone moiety in solution was determined by NMR and confirmed by x-ray diffraction. The copper(II) complexes were tested for their suitability as catalysts in 3 + 2 cycloaddition of azomethine imine to Me propiolate.

ACS Combinatorial Science published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C7H8INO, Application In Synthesis of 10517-44-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Xiong, Yang published the artcileVisible Light-Mediated Dearomative Hydrogen Atom Abstraction/ Cyclization Cascade of Indoles, Quality Control of 118-90-1, the publication is Angewandte Chemie, International Edition (2022), 61(18), e202200555, database is CAplus and MEDLINE.

The photochem. synthesis of yet unknown 2-oxospiro[azetidine-3,3′-indolines] (17 examples, 80-95% yield), 2,4-dioxospiro[azetidine-3,3′-indolines] (eight examples, 87-97% yield), and 1-oxo-1,3-dihydrospiro[indene-2,3′-indolines] (17 examples, 85-97% yield) is described. Starting from readily accessible 3-substituted indoles, a dearomatization of the indole core was accomplished upon irradiation at ¦Ë=420 nm in the presence of thioxanthen-9-one (10 mol%) as the sensitizer. Based on mechanistic evidence (triplet energy determination, deuteration experiments, byproduct anal.) it is proposed that the reaction proceeds by energy transfer via a 1,4- or 1,5-diradical intermediate. The latter intermediates are formed by excited state hydrogen atom transfer from suitable alkyl groups within the C3 substituent to the indole C2 carbon atom. Subsequent ring closure proceeds with pronounced diastereoselectivity to generate a 4- or 5-membered spirocyclic dearomatized product with several options for further functionalization.

Angewandte Chemie, International Edition published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C7H11N, Quality Control of 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ma, Kai Kai published the artcileFunctional and physical properties of commercial pulse proteins compared to soy derived protein, COA of Formula: C5H11NO2S, the publication is Future Foods (2022), 100155, database is CAplus.

In this study, the techno-functional and phys. attributes of various com. available pulse protein isolates were compared with those of soy protein isolate to evaluate their potential application as replacer for soy proteins in liquid and solid food formulations such as meat and dairy analogs. The water holding capacity, oil holding capacity, gelation properties, emulsifying properties, and color of faba bean (FPI), pea (PPI), lentil (LPI), and soy (SPI) protein isolates were therefore measured. SPI had a significantly higher water holding capacity (7.6 g/g) than the pulse protein isolates (2.2-5.1 g/g), but similar oil holding capacities were identified for SPI, FPI, and LPI. Especially LPI was more effective in droplet size reduction already at low concentrations (0.1-0.2%) compared to all other tested proteins, whereas FPI showed similar droplet size reduction efficiencies than SPI at higher concentrations (2-5%). Nevertheless, all of the plant proteins were capable of forming relatively small oil droplets (D32 = 1-3¦Ìm) at a protein-to-oil ratio of 1:10. Finally, FPI exhibited similar min. gelling concentrations to SPI, and especially LPI had a low coloring potential.

Future Foods published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, COA of Formula: C5H11NO2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lu, Dong published the artcileCu-Catalyzed Dual C-O Bonds Cleavage of Cyclic Ethers with Carboxylic Acids, NaI, and TMSCF₃ to Give Iodoalkyl Ester, Computed Properties of 118-90-1, the publication is Organic Letters (2022), 24(15), 2826-2831, database is CAplus and MEDLINE.

Herein, by dual C-O bonds cleavage of cyclic ethers with Cu-catalysis led to the development of a selective three-component coupling of com. available chems., carboxylic acids, ethers, and halogens to synthesize iodoalkyl esters RC(O)OR¹ [R = Ph, 2-furyl, 4-BrC₆H₄, etc.; R¹ = (CH₂)₄-I, n-decyl, (CH₂)₅-I, etc.] in the presence of TMSCF₃ was reported. This allowed for the concise synthesis of highly functionalized iodoalkyl esters directly. And the synthetic insect pheromones were also disclosed.

Organic Letters published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, Computed Properties of 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia