Tag: M.W=100-150

Lim, Ae Ran published the artcilePhysicochemical properties and structural dynamics of organic-inorganic hybrid [NH₃(CH₂)₃NH₃]ZnX₄ (X = Cl and Br) crystals, Related Products of catalysis-chemistry, the publication is Scientific Reports (2021), 11(1), 8408, database is CAplus and MEDLINE.

The phys. properties of the organic-inorganic hybrid crystals having the formula [NH₃(CH₂)₃NH₃]ZnX₄ (X = Cl, Br) were investigated. The phase transition temperatures (TC; 268K for Cl and 272K for Br) of the two crystals bearing different halogen atoms in their skeletons were determined through differential scanning calorimetry. The thermodn. properties of the two crystals were investigated through thermogravimetric anal. The structural dynamics, particularly the role of the [NH₃(CH₂)₃NH₃] cation, were probed through ¹H and ¹³C magic-angle spinning NMR spectroscopy as a function of temperature The ¹H and ¹³C NMR chem. shifts did not show any changes near TC. In addition, the ¹H spin-lattice relaxation time (T_1¦Ñ) varied with temperature, whereas the ¹³C T_1¦Ñ values remained nearly constant at different temperatures The T_1¦Ñ values of the atoms in [NH₃(CH₂)₃NH₃]ZnCl₄ were higher than those in [NH₃(CH₂)₃NH₃]ZnBr₄. The observed differences in the structural dynamics obtained from the chem. shifts and T_1¦Ñ values of the two compounds can be attributed to the differences in the bond lengths and halogen atoms. These findings can provide important insights or potential applications of these crystals.

Scientific Reports published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kang, Taek published the artcileIridium-Catalyzed Intermolecular Amidation of sp³ C-H Bonds: Late-Stage Functionalization of an Unactivated Methyl Group, HPLC of Formula: 6084-58-8, the publication is Journal of the American Chemical Society (2014), 136(11), 4141-4144, database is CAplus and MEDLINE.

Reported herein is the iridium-catalyzed direct amidation of unactivated sp³ C-H bonds. With sulfonyl and acyl azides as the amino source, the amidation occurs efficiently under mild conditions over a wide range of unactivated Me groups with high functional group tolerance. This procedure can be successfully applied for the direct introduction of an amino group into complex compounds and thus can serve as a powerful synthetic tool for late-stage C-H functionalization. Thus, e.g., [IrCp*Cl₂]₂/AgNTf₂-catalyzed amidation of ketoxime I with TsN₃ in 1,2-DCE in presence of catalytic AgOAc afforded sulfonamide II (90%).

Journal of the American Chemical Society published new progress about 6084-58-8. 6084-58-8 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is O-Isobutylhydroxylamine hydrochloride, and the molecular formula is C4H12ClNO, HPLC of Formula: 6084-58-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Gill, Dip Singh published the artcileA conductometric study of the complex formation between copper(I) perchlorate and some organic ligands in acetonitrile, Related Products of catalysis-chemistry, the publication is Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical & Analytical Chemistry (1998), 37A(12), 1079-1083, database is CAplus.

CuClO₄ solutions of different concentrations in MeCN were conductometerically titrated with solutions of thiourea (TU), N,N-dimethylthiourea (DMTU), N-phenylthiourea (NPTU), N,N-diphenylthiourea (DPTU), 1,10-phenanthroline (PHEN), 2,2′-bipyridine (BPY) and tri-Et phosphite (TEP) at 298 K. The plots of conductivity vs. moles of ligand added show significant decrease in conductivity followed by a region of almost constant conductivity The fall of conductivity in the cases of thiourea and substituted thioureas is linear while in all the other cases it is nonlinear. From these plots knowledge about the stoichiometry of the complexes formed between CuClO₄ and various ligands was derived. A 1:2 complex is observed between CuClO₄ and 1,10-phenanthroline and 2,2′-bipyridine and 1:4 complex with tri-Et phosphite. CuClO₄ forms complexes with thiourea and substituted thioureas, the stoichiometry of which strongly depends upon the concentrations of CuClO₄ and of the ligands used for the titration With N-phenylthiourea and N,N-diphenylthiourea, the complex formed has CuClO₄ to ligand ratio as 1:2 under the present conditions employed, while with thiourea and N,N-dimethylthiourea, the stoichiometry of the complexes formed between CuClO₄ and ligands is either 1:2 or 1:3 or 1:4 depending upon the conditions.

Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical & Analytical Chemistry published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kubczak, Malgorzata published the artcileHippophae rhamnoides L. leaf and twig extracts as rich sources of nutrients and bioactive compounds with antioxidant activity, Synthetic Route of 63-68-3, the publication is Scientific Reports (2022), 12(1), 1095, database is CAplus and MEDLINE.

Plants have served for centuries as sources of compounds useful for human health such as antioxidant, anti-diabetic and antitumor agents. They are also rich in nutrients that improve the human diet. Growing demands for these compounds make it important to seek new sources for them. Hippophae rhamnoides L. is known as a plant with health-promoting properties. In this study we investigated the chem. composition and biol. properties of bioactive components of ethanol extracts from leaves and twigs of H. rhamnoides L. Chem. components such as the total content of phenolic compounds, vitamins and amino acids and the antioxidant activities of these compounds in cellular and cell-free systems were assessed. The results suggest that the studied extracts are rich in bioactive compounds with potent antioxidant properties. Cytotoxicity and hemotoxicity assays showed that the extracts had low toxicity on human cells over the range of concentrations tested. Interaction with human serum albumin was investigated and conformational changes were observed Our results indicate that leaf and twig extracts of H. rhamnoides L. should be considered as a non-toxic source of bioactive compounds which may be of interest to the food, pharmaceutical and cosmetic industries.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Synthetic Route of 63-68-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kim, Dong CHan published the artcileSynthesis of new thiazolium betaines and the ring expansion reaction via 1,4-dipolar cycloaddition, Category: catalysis-chemistry, the publication is Journal of Heterocyclic Chemistry (1995), 32(5), 1581-6, database is CAplus.

The 1,4-dipolar cycloaddition of 3-phenyl-7-[N-phenyl(carbamoyl)]-5,6-dihydroimidazo[2,1-b]thiazolium betaine (I) with a series of aliphatic alkylating agents such as Et bromoacetate, ¦Á-chloroacetone, and Et 4-chloroacetoacetate gave a variety of new ring-expanded cycloadducts. E.g., (12RS,13SR)-12-acetyl-2,4-dioxo-1,3,9-triphenyl-6,7-dihydro-12H-thiazino[3′,4′:2,3]imidazo[1,2-a][1,3,5]triazine was prepared in 38% yield from I and ¦Á-chloroacetone.

Journal of Heterocyclic Chemistry published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hayashi, Yoshiki published the artcileBiosynthesis of S-adenosyl-methionine enhances aging-related defects in Drosophila oogenesis, Formula: C5H11NO2S, the publication is Scientific Reports (2022), 12(1), 5593, database is CAplus and MEDLINE.

Abstract: Tissue aging is a major cause of aging-related disabilities and a shortened life span. Understanding how tissue aging progresses and identifying the factors underlying tissue aging are crucial; however, the mechanism of tissue aging is not fully understood. Here we show that the biosynthesis of S-adenosyl-methionine (SAM), the major cellular donor of Me group for methylation modifications, potently accelerates the aging-related defects during Drosophila oogenesis. An aging-related increase in the SAM-synthetase (Sam-S) levels in the germline leads to an increase in ovarian SAM levels. Sam-S-dependent biosynthesis of SAM controls aging-related defects in oogenesis through two mechanisms, decreasing the ability to maintain germline stem cells and accelerating the improper formation of egg chambers. Aging-related increases in SAM commonly occur in mouse reproductive tissue and the brain. Therefore, our results raise the possibility suggesting that SAM is the factor related to tissue aging beyond the species and tissues.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Formula: C5H11NO2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rius, A. G. published the artcilePhysiological responses of Holstein calves to heat stress and dietary supplementation with a postbiotic from Aspergillus oryzae, Product Details of C5H11NO2S, the publication is Scientific Reports (2022), 12(1), 1587, database is CAplus and MEDLINE.

Increased ambient temperature causes heat stress in mammals, which affects physiol. and mol. functions. We have recently reported that the dietary administration of a postbiotic from Aspergillus oryzae (AO) improves tolerance to heat stress in fruit flies and cattle. Furthermore, heat-induced gut dysfunction and systemic inflammation have been ameliorated in part by nutritional interventions. The objective of this study was to characterize the phenotypic response of growing calves to heat stress compared to thermoneutral ad libitum fed and thermoneutral feed-restricted counterparts and examining the physiol. alterations associated with the administration of the AO postbiotic to heat-stressed calves with emphasis on intestinal permeability. In this report, we expand previous work by first demonstrating that heat stress reduced partial energetic efficiency of growth in control (45%) but not in AO-fed calves (62%) compared to thermoneutral animals (66%). While heat stress increased 20% the permeability of the intestine, AO postbiotic and thermoneutral treatments did not affect this variable. In addition, AO postbiotic reduced fecal water content relative to thermoneutral and heat stress treatments. Heat stress increased plasma concentrations of serum amyloid A, haptoglobin and lipocalin-2, and administration of AO postbiotic did not ameliorate this effect. In summary, our findings indicated that heat stress led to reduced nutrient-use efficiency and increased systemic inflammation. Results suggest that the AO postbiotic improved energy-use efficiency, water absorption, and the intestinal permeability in heat stress-mediated increase in gut permeability but did not reduce heat stress-mediated rise in markers of systemic inflammation.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Product Details of C5H11NO2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Koronkiewicz, Miroslawa published the artcileProapoptotic effects of new pentabromobenzylisothiouronium salts in a human prostate adenocarcinoma cell line, Recommanded Product: 1,1-Dimethylthiourea, the publication is Acta Poloniae Pharmaceutica (2012), 69(6), 1325-1333, database is CAplus and MEDLINE.

Prostate cancer is the second most common cancer in elderly men worldwide and its incidence rate is rising continuously. Agents capable of inducing apoptosis in prostate cancer cells seem a promising approach to treat this malignancy. In this study we describe the synthesis of a number of novel N- and N,N’-substituted S-2,3,4,5,6-pentabrornobenzylisothiouronium bromides and their activity against the human prostate adenocarcinoma PC3 cell line. All the compounds produced changes in mitochondrial transmembrane potential and cell cycle progression, showed a cytostatic effect and induced apoptosis in the tested cancer line in a concentrationand time-dependent manner. The most effective compounds ZKK-3, ZKK-9 and ZKK-13 produced, at 20 ¦ÌM concentration, apoptosis in 42, 46, and 66% of the cells, resp., after 48 h incubation. Two selected S-2,3,4,5,6-pentabromobenzylisothiouronium bromides (ZKK-3, ZKK-9) showed also a synergic proapoptotic effect with the new casein kinase II inhibitor 2-(4-methylpiperazin-l-yl)-4,5,6,7-tetrabromo-1H-benzimidazole (TBIPIP) in the PC3 cell line.

Acta Poloniae Pharmaceutica published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Recommanded Product: 1,1-Dimethylthiourea.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Takahashi, Rina published the artcileThe significance of NAD + metabolites and nicotinamide N-methyltransferase in chronic kidney disease, Name: (S)-2-Amino-4-(methylthio)butanoic acid, the publication is Scientific Reports (2022), 12(1), 6398, database is CAplus and MEDLINE.

Abstract: Dysregulation of NAD (NAD +) metabolism contributes to the initiation and progression of age-associated diseases, including chronic kidney disease (CKD). Nicotinamide N-methyltransferase (NNMT), a nicotinamide (NAM) metabolizing enzyme, regulates both NAD + and methionine metabolism Although NNMT is expressed abundantly in the kidney, its role in CKD and renal fibrosis remains unclear. We generated NNMT-deficient mice and a unilateral ureter obstruction (UUO) model and conducted two clin. studies on human CKD to investigate the role of NNMT in CKD and fibrosis. In UUO, renal NNMT expression and the degraded metabolites of NAM increased, while NAD + and NAD + precursors decreased. NNMT deficiency ameliorated renal fibrosis; mechanistically, it (1) increased the DNA methylation of connective tissue growth factor (CTGF), and (2) improved renal inflammation by increasing renal NAD + and Sirt1 and decreasing NF-¦ÊB acetylation. In humans, along with CKD progression, a trend toward a decrease in serum NAD + precursors was observed, while the final NAD + metabolites were accumulated, and the level of eGFR was an independent variable for serum NAM. In addition, NNMT was highly expressed in fibrotic areas of human kidney tissues. In conclusion, increased renal NNMT expression induces NAD + and methionine metabolism perturbation and contributes to renal fibrosis.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C6H8N2O2, Name: (S)-2-Amino-4-(methylthio)butanoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Abdel-Aal, Seham K. published the artcileSynthesis, Characterization, and Optical Properties of New Organic-Inorganic Hybrid Perovskites [(NH₃)₂(CH₂)₃]CuCl₄ and [(NH₃)₂(CH₂)₄]CuCl₂Br₂, Application of Propane-1,3-diamine dihydrochloride, the publication is Physica Status Solidi A: Applications and Materials Science (2021), 218(12), 2100036, database is CAplus.

Organic-inorganic hybrid perovskites (OIHs) are exceptionally promising sector of novel materials for optoelectronic applications. Herein, the OIHs of the formula [(NH₃)₂(CH₂)₃]CuCl₄ labeled by C₃CuCl and [(NH₃)₂(CH₂)₄]CuCl₂Br₂ labeled by C₄CuClBr are prepared by slow evaporation method. The synthesis process is achieved by mixing equimolar ethanolic solutions ratios (1:1) of their basic components (organic/inorganic). Characterizations of these materials using microchem. anal., energy dispersion X-ray (EDX) and X-ray diffraction (XRD) are discussed. The XRD is used to estimate the crystalline size for prepared compounds and found in the range of 38.8 and 48.8 nm for C₃CuCl and C₄CuClBr, resp. The vibrational spectra are studied by Fourier transformation IR spectroscopy (FTIR) and show the major diffraction peaks of compounds and their assignment. UV-region strong absorption is clarified in the optical properties studied for Cu hybrid, whereas the bandgap energy estimated via Kubelka-Munk equation and found 2.8 and 3.85 eV for C₃CuCl and C₄CuClBr, resp.

Physica Status Solidi A: Applications and Materials Science published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Application of Propane-1,3-diamine dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia