Tag: M.W=200-250

Preston, John S. published the artcileSolvent extraction of nickel and cobalt by mixtures of carboxylic acids and non-chelating oximes, Application of 2-(4-(tert-Butyl)phenoxy)acetic acid, the publication is Hydrometallurgy (1983), 11(1), 105-24, database is CAplus.

The effect of nonchelating oximes on the solvent extraction of Ni(II) and Co(II) by solutions of carboxylic acids (H₂A₂) in xylene was studied. Synergistic enhancements of extraction were found with aldoximes, but not with ketoximes. The synergistic effects were larger for Ni than for Co. The influence of the mol. structure of the oxime and carboxylic acid components upon the synergistic effects was rationalized in terms of the prevailing stereochem. and electronic effects. The extracted complexes were octahedral in structure, with the compositions NiA₂(oxime)₄ and CoA₂(oxime)₄. The mixed reagent systems may prove useful for the selective extraction of Ni in the presence of Co.

Hydrometallurgy published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Application of 2-(4-(tert-Butyl)phenoxy)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Purchase, Rupert published the artcileThe link between copper and Wilson’s disease, Computed Properties of 38260-01-4, the publication is Science Progress (St. Albans, United Kingdom) (2013), 96(3), 213-223, database is CAplus and MEDLINE.

A review. Wilson’s disease (hepatolenticular degeneration) is a rare inherited autosomal recessive disorder of copper metabolism leading to copper accumulation in the liver and extrahepatic organs such as the brain and cornea. Patients may present with combinations of hepatic, neurol. and psychiatric symptoms. Copper is the therapeutic target for the treatment of Wilson’s disease. Discovering the linking of copper to Wilson’s disease encompasses a study of enzootic neonatal ataxia in lambs in the 1930s, the copper-chelating properties of British Anti-Lewisite, and the chem. anal. for copper of the organs of deceased Wilson’s disease patients in the mid-to-late 1940s. Wilson’s disease is one of a number of copper-related disorders where loss of copper homeostasis as a result of genetic, nutritional or environmental factors affects human health.

Science Progress (St. Albans, United Kingdom) published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C6H20Cl2N4, Computed Properties of 38260-01-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Purchase, Rupert published the artcileThe purification of triethylenetetramine and its dihydrochloride for the treatment of Wilson’s disease, Recommanded Product: N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, the publication is Journal of Chemical Research (2005), 233-235, database is CAplus.

A method for the purification of triethylenetetramine and its dihydrochloride for use in the treatment of Wilson’s disease is reported. Thus, tech. grade triethylenetetramine (I) 1.18 Kg was mixed with water 262 mL and seeded with a few crystals of I hydrate; the precipitated I hydrate was collected and washed with THF and di-Et ether; the I hydrate was slurried with water 500 mL, cooled and treated with HCl to pH 7.8; evaporation of the aqueous solution (below 60¡ãC, 12 mmHg) and treatment of the residue with cold 95% ethanol afforded the dihydrochloride of I (854 g) containing a trace of impurity.

Journal of Chemical Research published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C6H20Cl2N4, Recommanded Product: N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ruiz Cruz, J. published the artcilePollution of natural waters by synthetic detergents. XVIII. Biodegradability of cationic surface-active agents by different standard methods, Recommanded Product: Dodecylamineacetate, the publication is Grasas y Aceites (Sevilla, Spain) (1987), 38(6), 383-8, database is CAplus.

There were no significant differences in cationic surfactant biodegradability results when tested by the Spanish standard and OECD methods. Several cationic surfactants were tested for their biodegradability in river waters and the results are presented.

Grasas y Aceites (Sevilla, Spain) published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Recommanded Product: Dodecylamineacetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jutz, Christian published the artcileUnsaturated aldehydes and ketones. I. Preparation of unsaturated aldehydes by a method involving the Vilsmeier reaction, SDS of cas: 16909-09-4, the publication is Chemische Berichte (1958), 850-61, database is CAplus.

cf. Vilsmeier, Chemiker-Ztg. 75, 133(1951). MeNPh(CH:CH)_nCHO (I) (n = 1), b_0.8 144-5¡ã, m. 48-9¡ã (Et₂O), was prepared from PhNHMe and CHú·CCHO (prepared from CHú·CCH₂OH by oxidation with CrO₃ in H₂O; cf. Huber, Dissertation, Munich, 1953). I (n = 2), properties not given [cf. Zincke and W¨¹rker, Ann. 338, 109(1905)] was formed by treating pyridine in the presence of PhNHMe with BrCN, and treating the resulting 1-methylanilino-1,3-pentadien-5-al methylanil bromide [cf. K?nig, J. Prakt Chem. 69, 134(1904)] (details not given). To I (n = 1) (0.1 mole) and 0.115 mole PhNMe₂ in 50 cc. absolute CHCl₃ or tetrahydrofuran below 0¡ã were added gradually 16 g. POCl₃, giving a mixture of salts of p-dimethylaminocinnamaldehyde methylanil, dark green, partially crystalline sirup, the separation of which was increased by adding petr. ether, and keeping at 20¡ã overnight. The upper phase was decanted and the sirup (II) extracted several times with petr. ether, taken up in 100 cc. MeOH and treated dropwise with 10% aqueous Na₂CO₃ until alk. The separated oil was steam distilled briefly to remove PhNHMe without loss of the partially volatile product. The cooled still residue was extracted with four 50-cc. portions of CHCl₃ giving 12-14 g. p-Me₂NC₆H₄CH:CHCHO (III), yellow leaflets, m. 141¡ã (K?nig, et al., C.A. 23, 381). An aliquot of II in MeOH with aqueous NaClO₄ gave p-dimethylaminocinnamaldehyde methylanil perchlorate (IV), C₁₈H₂₁N₂ClO₄, dark violet crystals, or bluish-green crystals with metallic luster, m. 158-9¡ã (Me₂CO-Et₂O, or MeOH-Et₂O). IV was also formed by warming III and PhNHMe at 50¡ã with the min. amount 2N HCl and adding NaClO₄. Formed similarly to III, from 8 g. each of I (n = 1), PhNEt₂, and POCl₃ was 8.6 g. p-Et₂NC₆H₄CH:CHCHO, yellow, m. 73-4¡ã (MeOH). Equimolar amounts of PhNMeCHO, POCl₃, and PhNMe₂ caused a separation of intermediate salts, from which was formed p-dimethylaminobenzaldehyde methylanil perchlorate, C₁₆H₁₉N₂ClO₄, pale yellow, m. 179-80¡ã(Me₂CO or MeOH-Et₂O), also formed from PhNMe₂ and Me₂NC₆H₄CHO in acid with HClO₄. Similarly, primary aromatic amines reacted with p-Me₂NC₆H₄CHO in aqueous acid solutions and then with NaClO₄ to form the corresponding anil perchlorates of the following: p-dimethylaminobenzaldehyde, C₁₅H₁₇N₂ClO₄, orange, m. 230-1¡ã (decomposition) (Me₂CO-Et₂O); p-dimethylaminocinnamaldehyde, C₁₇H₁₉N₂ClO₄, violet, m. 190¡ã (decomposition) (MeOH-Et₂O). I (n = 2) (9.4 g.) and 7 g. PhNMe₂ in tetrahydrofuran at -20¡ã with 9 g. POCl₃ and 5 g. PhNMe₂ treated as in the case of III gave, after a fully-described purification, 2 g. p-Me₂NC₆H₄(CH:CH)₂CHO, golden yellow, m. 156-7¡ã (sublimation in high vacuum followed by ligroine), whose methylanil perchlorate, blue violet with metallic luster, m. 205¡ã (decomposition) (Me₂CO-Et₂O). To 4 g. I (n = 1) and 5.6 g. 1-phenyl-1-(p-dimethylaminophenyl)ethylene in 25 cc. absolute C₆H₆, cooled, was added 10 cc. Ac₂O, shaken, and then treated dropwise with 2.5 g. anhydrous ZnCl₂ in 10 cc. AcOH, giving a violet-blue Zn complex salt. After removing the excess Ac₂O, AcOH, and C₆H₆ in vacuo, the residue dissolved in 200 cc. 25% MeOH was treated with 1 g. PhNHMe in 2N HCl, warmed to 50¡ã, filtered, and saturated NaClO₄ added to the filtrate, giving 9.3 g. 1-phenyl-1-(p-dimethylaminophenyl)-1,3-pentadien-5-al methylanil perchlorate (V), moss-green leaflets, m. 214-15¡ã (decomposition). V in CHCl₃ shaken with 20% aqueous Na₂CO₃ and filtered, the CHCl₃ separated, and the aqueous phase re?xtd. with CHCl₃; the combined extracts gave about 94% (crude) 1-phenyl-1-(p-dimethylaminophenyl)-1,3-pentadien-5-al, orange, m. 119.5-20.5¡ã (ligroine). I (n = 1) (0.1 mole) and 0.115 mole m-C₆H₄(OMe)₂ in CHCl₃, stirred and cooled below 0¡ã were treated with 16 g. POCl₃ in 20 cc. CHCl₃, warmed gradually to 35¡ã, stirred and treated with 200 cc. ligroine which caused the separation of 2 phases; the lower one was washed repeatedly with petr. ether, dissolved in 150 cc. CHCl₃, and washed successively with H₂O, 2N HCl, H₂O, 10% Na₂CO₃, and H₂O, dried and evaporated giving 17-17.5 g. 2,4-dimethoxycinnamaldehyde (VI), m. 99.5-100¡ã (C₆H₁₄ or aqueous MeOH); semicarbazone, m. 198-201¡ã (decomposition) (EtOH). VI oxidized in alc. NaOH with Ag₂O gave 2,4-(MeO)₂C₆H₃CH:CHCO₂H, m. 186-7¡ã. 1-Tetrahydroquinolinyl-1-propen-3-al (9.4 g.) and 10 g. CH₂(CO₂H)₂ in 60 cc. glacial AcOH, treated with 15 cc. Ac₂O and 2 g. ZnCl₂ in 5 cc. AcOH turned from brown to blue and evolved CO₂ slowly; after 24 hrs. 50 cc. MeOH was added, the mixture warmed to 50¡ã and poured into 1 l. 2% NaClO₄ solution, giving, on cooling a mixture of perchlorates, which was dried and extracted in a Soxhlet with 200 cc. Me₂CO. The extract treated with 70 cc. C₆H₆ gave 6 g. 1,7-bis(1-tetrahydroquinolinyl)heptamethine monoperchlorate, C₂₅H₂₇N₂ClO₄, long needles with blue metallic surface luster, m. 168¡ã (decomposition) (Me₂CO). The thimble residue, insoluble in Me₂CO, yielded 3 g. 1,3-bis(1-tetrahydroquinolinyl)trimethine monoperchlorate (properties not given). VII in CHCl₃ shaken with aqueous K₂CO₃ gave 1-tetrahydroquinolinyl-1,3,5-heptatrien-7-al, m. 149-50¡ã (C₆H₁₄) (cf. Dieterle and Riester, C.A. 31, 4911⁷). 1-Methylanilino-1-propen-3-al (8 g.) treated as in the preparation of VII gave an incompletely separated mixture (IX) of the methylanil perchlorates of 1-methylanilino-1,3,5-heptatrien-7-al and 1-methylanilino-1-propen-3-al (IXa). IX sintered 155¡ã, m. 163-4¡ã, and contained about 65-70% IXa (gaged from anal. data). Pure IXa, m. 166¡ã (decomposition), was prepared from I, PhNHMe and NaClO₄, in acid solution IX (4 g.) in 50 cc. CHCl₃, shaken with aqueous K₂CO₃, the aqueous phase extracted with CHCl₃, and the combined organic extracts washed with H₂O and Na₂CO₃, dried and evaporated gave 0.7-0.9 g. 1-methylanilino-1,3,5-heptatrien-7-al, orange-brown, m. 120-1¡ã (decomposition) (after extraction with ligroine, b. 60-80¡ã, discarding these extracts and then extracting with ligroine b. 80-120¡ã). p-Me₂NC₆H₄CHO (3 g.) and 3 g. PhNMe₂ in 20 cc. CHCl₃ was added dropwise to 3.5 g. POCl₃ in 10 cc. CHCl₃ at 0¡ã; after standing at 20¡ã and warming to 35¡ã, 100 cc. petr. ether were added and the resulting sirup (X) washed repeatedly with petr. ether. X, in little cold EtOH with aqueous NaClO₄ yielded 5.5-6.5 g. 4,4′-bis(dimethylamino)benzhydrol perchlorate, metallic blue leaflets, m. 161-3¡ã (decomposition) (varying with rate of heating) (Me₂CO-Et₂O).

Chemische Berichte published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, SDS of cas: 16909-09-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Karunakaran, K. published the artcileKinetics of oxidation of phenoxyacetic acids by quinolinium fluorochromate, Synthetic Route of 1798-04-5, the publication is Polish Journal of Chemistry (1998), 72(5), 916-924, database is CAplus.

The kinetics of oxidn of 21 PhOCH₂CO₂H derivatives by quinolinium fluorochromate were studied in binary solvent mixtures CH₂:CHCN has no effect on the oxidation rates in dipolar protic solvents, but in aprotic solvents it decreases the oxidation rates. In both solvent systems there exists an equilibrium prior to the rate-determining step, followed by irreversible decomposition of the complex. The calculated rate constants correlate well with Hammett ¦Ò values, and suitable mechanisms were proposed.

Polish Journal of Chemistry published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Synthetic Route of 1798-04-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kim, Sung-Gon published the artcileDiastereoselective organocatalytic Michael addition of 2-arylacetates having an electron-withdrawing group to nitro alkenes, Application In Synthesis of 4230-93-7, the publication is Letters in Organic Chemistry (2012), 9(8), 572-576, database is CAplus.

The first efficient organocatalytic conjugate addition reaction of 2-arylacetates and 2-arylacetonitriles having an electron-withdrawing group to nitro alkenes was achieved using a bifunctional amino thiourea catalyst. The reagents having NO₂-, CO₂Me-, and CN-functional groups on the aromatic ring can be used; the bifunctional catalyst, N-aminocyclohexyl-N’-bis(trifluoromethyl)phenylthiourea provided Michael adducts in the reaction of various nitro alkenes with broad generality in high yield and diastereoselectivity.

Letters in Organic Chemistry published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Application In Synthesis of 4230-93-7.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kondrat’ev, S. A. published the artcileEvaluation of activity selectivity of carbonic acids as floatation reagents, Quality Control of 2016-56-0, the publication is Fiziko-Tekhnicheskie Problemy Razrabotki Poleznykh Iskopaemykh (2012), 116-125, database is CAplus.

The article proves that the strength of a flotation agent depends on the surface pressure of its mols., or the ion-mol. associates, at the gas-solution contact. Based on the found relationship of the flotation strength and surface pressure of a reagent, the author determines collecting activity and selectivity of the reagent, and suggests a method for enhancing quality of separation of minerals having akin surface properties.

Fiziko-Tekhnicheskie Problemy Razrabotki Poleznykh Iskopaemykh published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Quality Control of 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kramer, Soeren published the artcileSynthesis of ¦Á-Substituted Primary Benzylamines through Copper-Catalyzed Cross-Dehydrogenative Coupling, Computed Properties of 457-68-1, the publication is Organic Letters (2019), 21(1), 65-69, database is CAplus and MEDLINE.

A copper-catalyzed route to ¦Á-substituted, primary benzylamines by C-H functionalization of alkylarenes is described. The method directly affords the amine hydrochloride salt. Catalyst loadings down to 0.1 mol % in combination with scalability, insensitivity to air and moisture, and no need for column chromatog. makes the procedure highly practical. The facile synthesis of the racemate of a blockbuster drug highlights the relevance for the development of pharmaceuticals. Preliminary mechanistic data are also included.

Organic Letters published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Computed Properties of 457-68-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kumar Yadav, Arvind published the artcile(NH₄)₂S₂O₈ mediated denitrative trifluoromethylation of ¦Â-nitrostyrenes: Synthesis of vinyltrifluoromethylated alkenes, Recommanded Product: 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, the publication is Results in Chemistry (2022), 100325, database is CAplus.

A metal-free denitrative trifluoromethylation of ¦Â-nitrostyrenes has been developed under mild reaction conditions using Langlois’ (CF₃SO₂Na) reagent to an easy access vinyltrifluoromethylated alkenes RCH:CHCF₃ (R = 3-MeOC₆H₄, 2-ClC₆H₄, 2-naphthyl, etc.). (NH₄)₂S₂O₈ used as a cheap radical initiator to produce CF₃ radical via desulfonylation at elevated temperature The product is predominantly trans (E)-selective and reaction is applicable to a wide range of the ¦Â-nitrostyrenes.

Results in Chemistry published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Recommanded Product: 1,2-Dimethoxy-4-(2-nitrovinyl)benzene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia