Tag: M.W=200-250

Toyota, Masahiro published the artcileSynthetic approach to stemodin – a novel stereocontrolled construction of the stemodane system by successive intramolecular Diels-Alder reactions., Name: Allyldiphenylphosphine oxide, the publication is Tetrahedron Letters (1992), 33(32), 4581-4, database is CAplus.

The tetracyclic compound I, possessing the stemodane skeleton, was synthesized from 1,4-cyclohexanedione monoethylene ketal. The key steps involve intramol. Diels-Alder reactions, namely ketone II to tricycle III and triene IV to I.

Tetrahedron Letters published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C11H8ClN3, Name: Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Toyota, Masahiro published the artcileSynthetic approach to stemodin (I) – a novel stereocontrolled construction of the stemodane system by the successive intramolecular Diels-Alder reactions, Application In Synthesis of 4141-48-4, the publication is Tetrahedron (1994), 50(4), 1093-104, database is CAplus.

The synthesis of the A, B, C and D ring part I of the diterpene stemodin (II) from 1,4-cyclohexanedione monoethylene ketal III by use of successive intramol. Diels-Alder reactions is described.

Tetrahedron published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C6H12F3NO5S, Application In Synthesis of 4141-48-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Giessel, Josephine M. published the artcileSubstituted cinnamic anhydrides act as selective inhibitors of acetylcholinesterase, Category: catalysis-chemistry, the publication is Bioorganic Chemistry (2019), 103058, database is CAplus and MEDLINE.

Cinnamic anhydrides have been shown to be more than reactive reagents, but they also act as inhibitors of the enzyme acetylcholinesterease (AChE). Thus, out of a set of 33 synthesized derivatives, several of them were mixed type inhibitors for AChE (from elec. eel). Thus, (E)-3-(2,4-dimethoxyphenyl)acrylic anhydride (2c) showed K_i = 8.30 ¡À 0.94 ¦ÌM and K_i‘ = 9.54 ¡À 0.38 ¦ÌM, and for (E)-3-(3-chlorophenyl)acrylic anhydride (2u) K_i = 8.23 ¡À 0.93 ¦ÌM and K_i‘ = 13.07 ¡À 0.46 ¦ÌM were measured. While being not cytotoxic to many human cell lines, these compounds showed an unprecedented and noteworthy inhibitory effect for AChE but not for butyrylcholinesterase (BChE).

Bioorganic Chemistry published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Saha, Satyajit published the artcileFunctionalized proline with double hydrogen bonding potential: highly enantioselective Michael addition of carbonyl compounds to ¦Â-nitrostyrenes in brine, Category: catalysis-chemistry, the publication is Tetrahedron Letters (2010), 51(40), 5281-5286, database is CAplus.

Simple synthetic manipulation of S-proline allows access to prolinamides as catalysts capable of double hydrogen bonding for enantioselective Michael addition reactions of carbonyl compounds to ¦Â-nitrostyrenes. It is shown that prolinamide catalyst I leads to addition products with a high diastereo- as well as enantioselectivity. The transition state structure involving the binding of electrophilic nitrostyrene via two H-bonds is believed to be further stabilized by ¦Ð,¦Ð stacking interactions mediated by the tosyl ring.

Tetrahedron Letters published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bohme, Horst published the artcileOptical studies on coumarins. II. Ultraviolet absorption of monohydroxycoumarins and derivatives, Application of (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, the publication is Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft (1957), 405-12, database is CAplus.

cf. C.A. 51, 15270h. In comparative studies of 4 monohydroxycoumarins, the longwave absorption bands were found to be moved bathochromically by introduction of a hydroxy group in the 6 or 7 position, while the corresponding maximum of 5-and 8-hydroxycoumarins lies at shorter wave lengths. As with coumarin itself 3 bands appear with 5-, 6-, and 8-hydroxycoumarin. 7-Hydroxycoumarin does not produce the medial bands with an inflection at 240 m¦Ì. Dihydroxy-trans-cinnamic acids are optically very similar to their methylated derivatives, but big differences were noted between hydroxycoumarins and dimethoxy-cis-cinnamic acids.

Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Application of (E)-3-(2,4-Dimethoxyphenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Filippov, L. O. published the artcileMechanism of starch adsorption on Fe-Mg-Al-bearing amphiboles, Synthetic Route of 2016-56-0, the publication is International Journal of Mineral Processing (2013), 120-128, database is CAplus.

The specific affinity of iron minerals for starch has been successfully exploited in the selective flocculation and flotation of iron ores. The same phenomenon complicates the flotation separation between iron oxides, i.e., magnetite and Fe-Mg-Al-bearing silicates. Adsorption isotherms were constructed, and the mechanisms of the adsorption of starch on quartz, magnetite and Fe-Mg-Al-bearing amphibole pargasite were discussed in this paper. The nature of the species adsorbed on minerals was determined by DRIFT and XPS spectroscopy. The flotation behavior of magnetite and silicates at pH 10 upon stirring in a starch solution was demonstrated. The adsorption and DRIFT study results concluded that starch is adsorbed both on quartz and amphiboles. However, the starch adsorption mechanism based on the chem. complexation is proposed to explain the strong depression effect of the starch during the magnetite and Fe-Mg-Al-bearing amphibole flotation with an amine compared with quartz.

International Journal of Mineral Processing published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Synthetic Route of 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Naumann, Dieter published the artcileNew syntheses and crystal structures of bis(fluorophenyl)mercury, Hg(R_f)₂ (R_f = C₆F₅, 2,3,4,6-F₄C₆H, 2,3,5,6-F₄C₆H, 2,4,6-F₃C₆H₂, 2,6-F₂C₆H₃), Category: catalysis-chemistry, the publication is Zeitschrift fuer Anorganische und Allgemeine Chemie (2005), 631(1), 122-125, database is CAplus.

Bis(fluorophenyl)mercury compounds, Hg(R_f)₂ (R_f = C₆F₅, 2,3,4,6-F₄C₆H, 2,3,5,6-F₄C₆H, 2,4,6-F₃C₆H₂, 2,6-F₂C₆H₃), were prepared in 75-93% yields by the reactions of HgF₂ with Me₃SiR_f in DMSO at room temperature for 48 or 72 h. An attempted reaction of Me₃SiC₆F₅ with Hg₂F₂ in DMSO was unsuccessful. The crystal structures of Hg(2,3,4,6-F₄C₆H)₂ (monoclinic, P2₁/n), Hg(2,3,5,6-F₄C₆H)₂ (monoclinic, C2/n), Hg(2,4,6-F₃C₆H₂)₂ (monoclinic, P2₁/c) and Hg(2,6-F₂C₆H₃)₂ (triclinic, P1?) are described.

Zeitschrift fuer Anorganische und Allgemeine Chemie published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Feldmann, Kai-Oliver published the artcileA versatile protocol for the quantitative and smooth conversion of phosphane oxides into synthetically useful pyrazolylphosphonium salts, HPLC of Formula: 4141-48-4, the publication is ChemSusChem (2011), 4(12), 1805-1812, database is CAplus and MEDLINE.

A convenient protocol for the smooth conversion of the resistant P:O bond in phosphane oxides R₂R¹P:O into a reactive P-N bond of synthetically useful pyrazolylphosphonium salts is described. A highly charged, oxophilic, phosphorus-centered trication [P₂(¦Ì-3,5-Me₂Pz)₃][OTf]₃ (1, 3,5-Me₂Pz = 3,5-dimethyl-1-pyrazolyl-N,N’) is employed as a deoxygenating reagent, and the reactions are conducted at room temperature with quant. yields. The resulting pyrazolylphosphonium cations [R₂R¹P(3,5-Me₂Pz)][OTf] (3a–g, R = Ph, Et, Bu; R₂ = CH:CMeCH₂CH₂; R¹ = Ph, Me, Et, CH₂CH:CH₂) are valuable synthetic intermediates and are used for the synthesis of a variety of organophosphorus compounds Protonation of 3a facilitates P-N-bond cleavage and reduction or substitution reactions. Triphenylphosphine may be obtained by electrochem. or LiAlH₄ reduction of 3a. Alkylation of 3a with BuLi gave the phosphonium ylide, Ph₃P:CHPr, which was used in Wittig olefination of 2-nitrobenzaldehyde. This represents a new approach towards the transformation of the rather inert phosphoryl group under very mild reaction and workup conditions and aims towards alternatives to existing reduction methods for phosphane oxide functionalization.

ChemSusChem published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, HPLC of Formula: 4141-48-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bevers, Susan published the artcileNaphthalene- and Perylene-Based Linkers for the Stabilization of Hairpin Triplexes, COA of Formula: C10H25NO2Si, the publication is Journal of the American Chemical Society (2000), 122(25), 5905-5915, database is CAplus.

Planar perylene- and naphthalene-based diimide linkers can be employed to tether the Watson-Crick and the Hoogsteen strands of a DNA triplex, thus providing conjugates capable of targeting single-stranded nucleic acids with the formation of hairpin triplexes. The planar linkers are designed to bridge the terminal base triplet of the three-stranded complex and provide base-stacking interactions with all three residues. Sixteen complexes have been prepared, eight with each linker, half with RNA (R) targets and half with DNA (D) targets. The conjugate sequences are composed of two strands of DNA, two of 2′-O-Me RNA (M), or one of each. In comparison to similar complexes formed with a hexa(ethylene glycol) linker, the planar linkers enhance the T_M values for the complexes by as much as 28 ¡ãC with ¦¤G values indicating as much as 12.3 kcal/mol of stabilization relative to the simple glycol linker. All sixteen complexes have been characterized by T_M measurements and ¦¤G determinations That ¦Ð-stacking interactions are present between the linkers, and the nucleobases can be inferred from the quenching of the perylene fluorescence upon complex formation, and the observation of an absorbance vs temperature transition for the naphthalene-based linker at 383 nm and for the perylene-based linker monitored at 537 nm.

Journal of the American Chemical Society published new progress about 215297-17-9. 215297-17-9 belongs to catalysis-chemistry, auxiliary class Linker,PROTAC Linker, name is 2-(2-((tert-Butyldimethylsilyl)oxy)ethoxy)ethan-1-amine, and the molecular formula is C10H25NO2Si, COA of Formula: C10H25NO2Si.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Onuska, Nicholas P. R. published the artcileAnti-Markovnikov Hydroazidation of Activated Olefins via Organic Photoredox Catalysis, Synthetic Route of 22693-41-0, the publication is Synlett (2020), 31(1), 55-59, database is CAplus and MEDLINE.

Herein was disclosed a method for the anti-Markovnikov hydroazidation of activated olefins, catalyzed by an organic acridinium salt under irradiation from blue LEDs to afford (azidoalkyl)arenes such as ArCH(R)CH(R¹)N₃ [R = H, Me, Ph; R¹ = H, Me, CH₂OTBS, etc.; Ar = Ph, 2-thienyl, 2-naphthyl, etc.]. This method was applicable to a variety of substituted and terminal styrenes and several vinyl ethers, yielding synthetically versatile hydroazidation products in moderate to excellent yield.

Synlett published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Synthetic Route of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia