Tag: M.W=200-250

Bardin, V. V. published the artcileReactions of polyfluoroaryl bromides and iodides with C-, Si-, Ge-, Sn- and Pb-electrophiles and tris(dialkylamino)phosphines, Safety of Trimethyl(perfluorophenyl)silane, the publication is Journal of Fluorine Chemistry (1991), 53(2), 213-31, database is CAplus.

The reactions of RBr (R = polyfluoroaryl, e.g., C₆F₅) or RI with P(NEt₂)₃ and R¹₃MX (R¹ = alkyl; M = Si, Ge, Sn, Pb; X = Cl, Br) gave RMR¹₃. Reactions of C₆F₅Br with P(NEt₂)₃ and C electrophiles [MeI, C₆F₅CF₃ and (CF₃)₂C:CFC₂F₅] gave pentafluorophenylation products.

Journal of Fluorine Chemistry published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Safety of Trimethyl(perfluorophenyl)silane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bardin, V. V. published the artcileReaction of polyfluoroaromatic compounds with electrophilic agents in the presence of tris(dialkylamino)phosphine. I. Synthesis of trialkylsilyl(germyl, stannyl or plumbyl)polyfluorobenzenes, Formula: C9H9F5Si, the publication is Zhurnal Obshchei Khimii (1992), 62(10), 2342-9, database is CAplus.

In the presence of an equimolar amount of P(NEt₂)₃, polyfluorophenyl bromides react with alkylhalosilanes, -germanes, -stannanes, and -plumbanes to give the corresponding phenyl(alkyl) derivatives of these elements plus a phosphonium salt. Electron-donating groups in the 4-position of the polyfluorophenyl bromide slow the reaction, whereas electron-accepting groups accelerate it.

Zhurnal Obshchei Khimii published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Formula: C9H9F5Si.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chevalley, Alice published the artcileModel Studies for a Ring-Closing Metathesis Approach to the Bafilomycin Macrolactone Core from a 2,2-Dimethoxy Tetraenic Ester Precursor, Name: Allyldiphenylphosphine oxide, the publication is European Journal of Organic Chemistry (2013), 2013(36), 8265-8278, database is CAplus.

A ring-closing metathesis strategy is reported for the construction of the 16-membered macrolactone core of bafilomycin. One decisive key feature is the presence of a 2,2-dimethoxy-ketal functionality at C-2 that provides the required flexibility to the tetraene acid ester precursor, allowing the ring-closing metathesis reaction to take place. Three different model esters of increasing complexity were successfully subjected to the 1,3-diene-ene ring-closing metathesis reaction. The best promoter for the simplest esters was the Grubbs first-generation pre-catalyst. A Hoveyda-Grubbs-type trifluoroacetamide-containing pre-catalyst developed by Mauduit’s group gave satisfactory results for the most complex ester. In all experiments, the (12Z)-configured isomer was obtained as the major product. Subsequent microwave-promoted methanol elimination was achieved on the simplest model compound using camphorsulfonic acid (CSA) as a catalyst. Under these conditions, a (E/Z)-isomerization of the double bond at C-4, as well as ca. 50% isomerization of the (12Z)-double bond into the corresponding (12E)-isomer, were observed The synthesis of the target compounds was achieved using (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dicarboxylic acid 4,5-di-Me ester as a chiral source. The title compounds thus formed included a maacrolactone (macrolide) (I) and related substances.

European Journal of Organic Chemistry published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Name: Allyldiphenylphosphine oxide.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shumaila, Abdullah M. A. published the artcileDiastereoselective synthesis of tetrasubstituted-octahydro-3,6-diazacarbazoles and tetrasubstituted-3,6-diazacarbazoles via double Pictet-Spengler reaction, Category: catalysis-chemistry, the publication is Tetrahedron Letters (2011), 52(21), 2661-2663, database is CAplus.

Pictet-Spengler condensation of 2,5-bis(2-phenyl-1-aminoethyl)pyrrole using glacial acetic acid afforded only one diastereomer of unreported tetrasubstituted-octahydro-3,6-diazacarbazoles, e.g. I. These were readily dehydrogenated to tetrasubstituted-3,6-diazacarbazoles, e.g. II. The stereoselectivity in the Pictet-Spengler reaction has been demonstrated using single crystal X-ray anal.

Tetrahedron Letters published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C6H8O6, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shumaila, Abdullah M. A. published the artcileSynthesis of tetrahydro-5-azaindoles and 5-azaindoles using Pictet-Spengler reaction-appreciable difference in products using different acid catalysts, Recommanded Product: 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, the publication is Tetrahedron (2011), 67(5), 936-942, database is CAplus.

Pictet-Spengler condensation of 2-(aryl)-2-(1H-pyrrol-2-yl)ethanamines using conventional acid catalysts like TMSCl or TFA resulted in the formation of substituted 5-azaindoles involving a tandem one pot four step reaction sequence. By contrast, use of glacial acetic acid furnished the targeted tetrahydro-5-azaindoles in diastereoselective manner. These were readily dehydrogenated to 5-azaindoles.

Tetrahedron published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C5H11NO2S, Recommanded Product: 1,2-Dimethoxy-4-(2-nitrovinyl)benzene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shah, V. H. published the artcileSome new aryloxyacetic acid, Computed Properties of 5411-14-3, the publication is Journal of the Institution of Chemists (India) (2003), 75(2), 62-63, database is CAplus.

A number of aryloxyacetic acids were prepared The constitution of the products was supported by elemental analyses, IR and PMR spectral data. The products were screened for antimicrobial activity. All the compounds showed moderate activity.

Journal of the Institution of Chemists (India) published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C14H10N2O, Computed Properties of 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

de Silva, Nilamuni H. published the artcileMicrowave-assisted rapid synthesis of spirooxindole-pyrrolizidine analogues and their activity as anti-amyloidogenic agents, Synthetic Route of 4230-93-7, the publication is Bioorganic Chemistry (2021), 105128, database is CAplus and MEDLINE.

A library of Sox-pyrrolizidines was rapidly prepared by microwave-assisted, one-pot, three-component, 1,3-dipolar cycloaddition of azomethine ylides from L-proline and isatin, with various ¦Â-nitrostyrenes. Nitro-Sox compounds, I, 4d and 4e inhibit HEWL amyloid fibril formation by ThT studies with percentages of fluorescence intensity of 55.4, 42.9 and 40.3%, resp. Further studies with MTT assay, Raman spectroscopy, TEM and mol. docking supported these promising candidates for activity against amyloid misfolding, a phenomenon leading to Alzheimer’s disease pathol.

Bioorganic Chemistry published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Synthetic Route of 4230-93-7.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhou, Hua published the artcileThe research to the condition of catalytic degradation of borofluoric acid diazonium salt, Application of Bis(4-fluorophenyl)methane, the publication is Shandong Huagong (2009), 38(1), 18-20, database is CAplus.

The influencing factors of the the catalytic degradation of borofluoric acid diazonium salt were discussed, which was the key step to synthesize 4,4′- difluorobenzophenone. It was found that with iron powder as catalyst and adding dry diazonium salt to toluene whose volume was triple-weight of diazonium salt, the reaction could be occurred smoothly; and with those conditions the yield of the reaction could be up to 85% and the purity could be 94% (with GC detection).

Shandong Huagong published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C23H20BN, Application of Bis(4-fluorophenyl)methane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

McMurtry, Brandon M. published the artcileContinuous Nucleation and Size Dependent Growth Kinetics of Indium Phosphide Nanocrystals, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine, the publication is Chemistry of Materials (2020), 32(10), 4358-4368, database is CAplus.

Aminophosphines derived from N,N’-disubstituted ethylenediamines (R-N(H)CH₂CH₂N(H)-R; R = ortho-tolyl, Ph, benzyl, iso-Pr, and n-octyl) were used to adjust the kinetics of InP nanocrystal formation by more than 1 order of magnitude. UV-visible absorption and ³¹P NMR measurements demonstrate that the rate of nanocrystal formation is limited by the precursor reactivity. At low temperature (180¡ãC), crystal nucleation is concurrent with growth throughout the reaction, rather than occurring in a burst at early times. The low temperature produces a narrow range of small sizes (d = 4.2-4.9 nm) regardless of the precursor used. Higher temperatures (up to 270¡ãC) promote growth to larger sizes (d ¡Ü 7.8 nm), shorten the nucleation period, and create conditions where the final size is controlled by the precursor conversion reactivity. The temperature dependence is proposed to arise from growth kinetics that slow as the nanocrystal size increases, a novel surface attachment limited size distribution-focusing mechanism. Such a mechanism supports a narrow size distribution without separating the nucleation and growth phases.

Chemistry of Materials published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Benz, Sebastian published the artcileCatalysis with Pnictogen, Chalcogen, and Halogen Bonds, Recommanded Product: Trimethyl(perfluorophenyl)silane, the publication is Angewandte Chemie, International Edition (2018), 57(19), 5408-5412, database is CAplus and MEDLINE.

Halogen- and chalcogen-based ¦Ò-hole interactions have recently received increased interest in non-covalent organocatalysis. However, the closely related pnictogen bonds have been neglected. In this study, authors introduce conceptually simple, neutral, and monodentate pnictogen-bonding catalysts. Solution and in silico binding studies, together with high catalytic activity in chloride abstraction reactions, yield compelling evidence for operational pnictogen bonds. The depth of the ¦Ò holes is easily varied with different substituents. Comparison with homologous halogen- and chalcogen-bonding catalysts shows an increase in activity from main group VII to V and from row 3 to 5 in the periodic table. Pnictogen bonds from antimony thus emerged as by far the best among the elements covered, a finding that provides most intriguing perspectives for future applications in catalysis and beyond.

Angewandte Chemie, International Edition published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Recommanded Product: Trimethyl(perfluorophenyl)silane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia