Tag: M.W=200-250

Rajadurai, Maruthamuthu published the artcilePhytochemical profiling of medically significant crude extract using GC-MS analysis, Application of (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, the publication is International Journal of Current Pharmaceutical Research (2018), 10(6), 16-20, database is CAplus.

The objective of this research is to identify the phytochem. constitutions present in Natural crude extract which obtained from Thumlappati district. Kidney stone is one of the most clin. disorder arising nowadays. They are existing due to the depletion of the urine and disproportionate execration of the components such as oxalate, phosphate, uric, cysteine, and struvite. Many alopathy medicine are not effectively curable in the case of kidney stone, consequently people are in need of traditional medicine system. Thus there is a great demand for research on potential inhibitor from natural products for dissolving kidney stone. In present work deals with an unknown crude extract collected from G. Thumlappati, Battalagundu Dindugal district Tamil Nadu. The crude extract of phytochem. are analyzed by using GCMS method. Thus the sample has some bioactive compound to discharge the stone particles. So we subjected the crude extract sample to GC-MS process which reveals 210 compounds in 21 different peaks. This studies forms a basis for the biol. characterization and importance of bioactive compounds were identified.

International Journal of Current Pharmaceutical Research published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Application of (E)-3-(2,4-Dimethoxyphenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chakravarti, Duhkhaharan published the artcileSynthesis of coumarins from o-hydroxyaryl alkyl ketones. II. Formation of o-coumaric acids from o-hydroxyaldehydes, Formula: C11H12O4, the publication is Journal of the Indian Chemical Society (1939), 389-92, database is CAplus.

cf. C. A. 32, 7026.9; 33, 549.4. The Me ethers of the o-HO aldehydes condense with EtO₂CCH₂Br (I) and EtO₂CCHBrMe (II) to form trans-cinnamic esters, which do not yield coumarins on heating with HI or on standing with cold H₂SO₄ as do the esters obtained from o-hydroxyaryl alkyl ketones. A mixture of 11 g. o-MeOC₆H₄CHO in 50 cc. anhydrous benzene, 6 g. Zn wool and 16 g. I was heated at 100¡ã for 2 h. and poured into ice-cold dilute H₂SO₄. The washed and dried benzene layer was evaporated down and distilled, yielding 11 g. of o-MeOC₆H₄CH(OH)CH₂CO₂Et, b₁₀ 150-4¡ã, which was converted by heating with 6 g. SOCl₂ and 9 g. pyridine in ether into 10 g. Et 2-methoxy-trans-cinnamate, C₁₂H₁₄O₃, b₈ 150¡ã, hydrolyzed to 2-methoxy-trans-cinnamic acid, m. 182¡ã, identical with a specimen prepared from o-coumaric acid by methylation with Me₂SO₄ and hydrolysis. Similarly, o-MeOC₆H₄CHO was converted by Reformatski¨«’s reaction with Zn and II to o-MeC₆H₄CH(OH)CHMeCO₂Et, b₄ 155¡ã, transformed by SOCl₂ in the presence of pyridine to Et 2-methoxy-¦Á-methyl-trans-cinnamate, C₁₃H₁₆O₃, b₄ 150-5¡ã, hydrolyzed by alc. KOH to the corresponding acid, m. 102¡ã. Condensation of 2,4-(MeO)₂C₆H₃CHO with I gave 2,4-(MeO)₂C₆H₃CH(OH)CH₂CO₂Et, b₈ 180-4¡ã, dehydrated to the cinnamic ester, b₈ 180-4¡ã, hydrolyzed to 2,4-dimethoxy-trans-cinnamic acid, m. 184¡ã. To study the influence of a Ph substituent on the formation of trans-cinnamic esters, 8.5 g. of 5,2-Cl(MeO)C₆H₃CHO was condensed with 8.5 g. I to the propionate (8 g.) which, on dehydration with SOCl₂, gave 6 g. of Et 2-methoxy-5-chloro-trans-cinnamate, C₁₂H₁₃ClO₃, b₆ 170¡ã, hydrolyzed to the corresponding acid (III), m. 191¡ã. A sample of authentic III was prepared by treating 6-chlorocoumarin with HgO, methylating and hydrolyzing with alc. KOH. Thus it is shown that if there are no ¦Â-alkyl groups in the resulting cinnamic ester, the latter has the trans configuration. Otherwise the esters have the cis configuration and readily form coumarins. The 2-MeO aldehydes are useful starting materials for the preparation of o-coumaric acid derivatives in satisfactory yields. Condensation of 10 g. of 2,4-(MeO)₂C₆H₃Ac (IV) with 9 g. II and distillation of the product yielded 8.5 g. of Et 2,4-dimethoxy-¦Á,¦Â-dimethyl-cinnamate (V), b₆ 180-2¡ã, converted by standing overnight in cold H₂SO₄ (d. 1.84) to 3,4-dimethyl-7-methoxycoumarin, m. 140¡ã. Heating V (1 g.) with 7 cc. HI (d. 1.7) at 140¡ã for 2 h. gave colorless needles of 3,4-dimethyl-7-hydroxycoumarin, m. 256¡ã, on recrystallization from alc. Similarly, condensation of 10 g. IV with I gave an unsaturated ester, b₆ 174¡ã, on vacuum distillation No ring closure was effected by heating with HI or on treatment with cold H₂SO₄. Hydrolysis gave the known 2,4-dimethoxy-¦Â-methylcinnamic acid, m. 145¡ã.

Journal of the Indian Chemical Society published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Formula: C11H12O4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Holmes, Michael E. published the artcileControlling the anisotropy of holographic polymer-dispersed liquid-crystal gratings, Related Products of catalysis-chemistry, the publication is Physical Review E: Statistical, Nonlinear, and Soft Matter Physics (2002), 65(6-2), 066603/1-066603/4, database is CAplus and MEDLINE.

In this work the optical properties of elec. switched transmission gratings fabricated holog. using polymer-dispersed liquid-crystal (PDLC) materials were investigated. It was found that the PDLC mixture can be used to control the diffractive properties of the liquid-crystal composite gratings. In one limit the gratings are highly isotropic and in the other limit the gratings are highly anisotropic with a large birefringence. The exptl. results are compared to theories that include the birefringence of the grating. From theor. fits to the exptl. data, measurements of the liquid-crystal distribution and alignment are obtained.

Physical Review E: Statistical, Nonlinear, and Soft Matter Physics published new progress about 2909-77-5. 2909-77-5 belongs to catalysis-chemistry, auxiliary class Amine,Benzene, name is 2,6-Diisopropyl-N,N-dimethylaniline, and the molecular formula is C14H23N, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Xue, Yulan published the artcileSeparation of aluminum hydroxide and gypsum by flotation during wastewater treatment, Quality Control of 2016-56-0, the publication is Zhongnan Kuangye Xueyuan Xuebao (1983), 21-8, database is CAplus.

An artificial acid mine water containing 500 mg Al/L and 600 mg SO₄^2-/L was neutralized by CaCO₃; the products were treated by flotation separation for gypsum removal using dodecylammonium?acetate (DAA) [2016-56-0] as a collector and starch as a depressor for Al(OH)₃ settling. Acid mine water from Matsuo is so treated with 97% recovery for gypsum and 96% for Al(OH)₃.

Zhongnan Kuangye Xueyuan Xuebao published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is 0, Quality Control of 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kumar, Tarun published the artcileSynthesis of Aminophenanthrenes and Benzoquinolines via Hauser-Kraus Annulation of Sulfonyl Phthalide with Rauhut-Currier Adducts of Nitroalkenes, Formula: C10H11NO4, the publication is Organic Letters (2017), 19(16), 4283-4286, database is CAplus and MEDLINE.

The Hauser-Kraus reaction of sulfonyl phthalide with nitroalkene derivatives provides access to aminophenanthrenes, including phenanthrene-substituted amino acids and benzoquinolines. The intermediate quinones bearing a key ketoalkyl moiety undergoes facile intramol. enamine cyclization. Interestingly, enamines derived from primary and secondary amines undergo cyclization via C-centered nucleophilic attack to provide aminophenanthrenes I [R¹R² = (CH₂)₄, (CH₂)₂O(CH₂)₂, etc.; Ar = 4-FC₆H₄, 3-MeOC₆H₄, etc.] whereas those derived from ammonia undergo cyclization via N-centered nucleophilic attack leading to benzoquinolines II (Ar = 4-FC₆H₄, 4-MeOC₆H₄, Ph, etc.). A one-pot protocol for the direct transformation of phthalides and nitroalkene derivatives to aminophenanthrenes and benzoquinolines has also been developed.

Organic Letters published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Formula: C10H11NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Prathap, S. published the artcileGrowth, optical and thermal studies on N-benzyl-2 methyl-4-nitroaniline, Related Products of catalysis-chemistry, the publication is IOP Conference Series: Materials Science and Engineering (2015), 012033/1-012033/4, database is CAplus.

In this work we present the growth, optical and thermal studies of the nonlinear organic mol. crystal, N-benzyl-2-methyl-4-nitroaniline (BNA). BNA is also a good THz electromagnetic waves emitter in 0.1 – 15 THz range. Nonlinear optical property of the crystal has been confirmed using the Kurtz powder technique and a study of its second harmonic generation efficiency in comparison with KDP has been made. Knoop hardness test was carried out and its Young’s modulus was calculated Thermal behavior of the crystal was investigated by TG-DTG analyses.

IOP Conference Series: Materials Science and Engineering published new progress about 201157-13-3. 201157-13-3 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is N-Benzyl-2-methyl-4-nitroaniline, and the molecular formula is C14H14N2O2, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yanagisawa, Toshihiko published the artcileSubacute and chronic toxicity studies of triethylenetetramine dihydrochloride (TJA-250) by oral administration to F-344 rats, Safety of N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, the publication is Journal of Toxicological Sciences (1998), 23(Suppl. 4), 619-642, database is CAplus and MEDLINE.

Triethylenetetramine dihydrochloride (trientine-2HCl, TJA-250), a copper chelating agent used to treat Wilson’s disease, was administered orally to male and female F-344 rats for 4 or 8 wk at dosages of 0, 100, 350 or 1200 mg/kg/day or for 26 wk at dosages of 50, 175 or 600 mg/kg/day. Two males receiving 1200 mg/kg/day died during week 8 of treatment. In males receiving 1200 mg/kg/day during weeks 5 to 8 of treatment, body weight gain and food consumption were decreased and hunched posture and thin build were observed During week 4 or 8 of treatment urinalysis revealed, for males receiving 100 mg/kg/day or animals receiving 350 mg/kg/day or more, increased electrolyte outputs possibly due to the hydrochloride nature of trientine-2HCl, with low plasma alk. phosphatase activities evident in animals receiving 350 or 1200 mg/kg/day. After 4 and 8 wk, and during 8 wk of treatment, high lung weights and bronchiolar epithelium hypertrophy and broncho-alveolar pneumonia were recorded for animals receiving 1200 mg/kg/day, and submucosal acute inflammation within the glandular region of the stomach was recorded for males receiving 350 or 1200 mg/kg/day and in all treated female groups. One male receiving 175 mg/kg/day and three males receiving 600 mg/kg/day died, showing lung changes in the 26 wk study. The body weight gain of animals receiving 600 mg/kg/day was slightly decreased. Blood chem. and urinalysis examinations showed changes similar to those indicated in the 4- or 8-wk study. The low plasma copper concentrations seen in males receiving 600 mg/kg/day, the slightly low liver copper concentrations found in animals receiving 600 or 175 mg/kg/day and the high urinary copper concentrations found in all treated groups, are attributed to the pharmacol. action of trientine-2HCl. Histopathol. revealed a dosage-related incidence and severity of focal chronic interstitial pneumonitis accompanied by fibrosis of the alveolar walls in females receiving 175 mg/kg/day or more and all treated male groups, but no significant pathol. changes in the stomach. Apart from the histol. changes found in the lung, all the above changes were reversible. In conclusion, the NOAEL of trientine-2HCl in this 26-wk study was considered to be 50 mg/kg/day for females and less than 50 mg/kg/day for males.

Journal of Toxicological Sciences published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C4H3Cl2N3, Safety of N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Stoica, Ligia published the artcileKinetics of ionic and ion-molecular flotation. Part II. Flotation of copper(II) with amine collectors, Recommanded Product: Dodecylamineacetate, the publication is Revistade Chimie (Bucharest, Romania) (1991), 42(1-3), 63-6, database is CAplus.

The kinetics of the ion-mol. flotation of Cu(11) from a CuSi₄ solution by using laurylamine and stearylamine acetates as collector was studied. The graphical representation of the exptl. results show that flotation is a 1st order reaction with both collectors.

Revistade Chimie (Bucharest, Romania) published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C19H21N3O3S, Recommanded Product: Dodecylamineacetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rueda-Becerril, Montserrat published the artcileDirect C-F Bond Formation Using Photoredox Catalysis, Safety of 2-(4-(tert-Butyl)phenoxy)acetic acid, the publication is Journal of the American Chemical Society (2014), 136(6), 2637-2641, database is CAplus and MEDLINE.

We have developed the first example of a photoredox catalytic method for the formation of carbon-fluorine (C-F) bonds. The mechanism has been studied using transient absorption spectroscopy and involves a key single-electron transfer from the ³MLCT (triplet metal-to-ligand charge transfer) state of Ru(bpy)₃²⁺ to Selectfluor. Not only does this represent a new reaction for photoredox catalysis, but the mild reaction conditions and use of visible light also make it a practical improvement over previously developed UV-mediated decarboxylative fluorinations.

Journal of the American Chemical Society published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Safety of 2-(4-(tert-Butyl)phenoxy)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Karishma, Pidiyara published the artcileReducing-Agent-Free Convergent Synthesis of Hydroxyimino-Decorated Tetracyclic Fused Cinnolines via Rh^III-Catalyzed Annulation Using Nitroolefins, Recommanded Product: 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, the publication is Journal of Organic Chemistry (2021), 86(3), 2734-2747, database is CAplus and MEDLINE.

A mild Rh-catalyzed method was developed for the synthesis of hydroxyimino functionalized indazolo[1,2-a]cinnolines and phthalazino[2,3-a]cinnolines by reductive [4 + 2] annulation between 1-arylindazolones and 2-aryl-2,3-dihydrophthalazine-1,4-diones with varied nitroolefins. The targeted oxime decorated tetracyclic fused cinnolines were synthesized via sequential C-H activation/olefin insertion/reduction under reducing-agent-free conditions.

Journal of Organic Chemistry published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Recommanded Product: 1,2-Dimethoxy-4-(2-nitrovinyl)benzene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia