Month: November 2022

Gale, Philip A. published the artcileAcyclic indole and carbazole-based sulfate receptors, SDS of cas: 17351-61-0, the publication is Chemical Science (2010), 1(2), 215-220, database is CAplus.

The anion complexation properties of acyclic receptors consisting of diindolylurea groups appended with amide, amidoindole or amidocarbazole groups have been studied. The receptors selectively bind and encapsulate sulfate via either 6 or 8 H bonds. Receptors containing 8 H bond donors perturb the pK_a of bound dihydrogen phosphate and bicarbonate to the extent that they are deprotonated by free anion in solution

Chemical Science published new progress about 17351-61-0. 17351-61-0 belongs to catalysis-chemistry, auxiliary class Phase Transfer Catalyst, name is Tetraethylammonium hydrogencarbonate, and the molecular formula is C9H21NO3, SDS of cas: 17351-61-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kuroda, Tokuyuki published the artcileSynthesis and biological activity of novel mitomycin C analogs derived from mitomycin A, Related Products of catalysis-chemistry, the publication is Journal of Heterocyclic Chemistry (1994), 31(1), 113-19, database is CAplus.

A variety of mitomycin C analogs were synthesized from mitomycin A and their biol. activities were studied. Mitomycin A (I) underwent nucleophilic displacement reactions involving intramol. hydrogen migrations upon treatment with nitrogen nucleophiles bearing mobile hydrogens, but the mode of hydrogen migration depended on the nature of the nucleophiles. The reaction with alkoxyamines gave oximes II (R = Me, CH₂CHMe₂). However, the reaction with hydroxylamine and benzohydrazine afforded imines III (R¹ = OH, NHBz). These products were converted into various types of mitomycin C derivatives by methylation with Me iodide or di-Me sulfate. The mechanistic features of these reactions are discussed. The in vitro and in vivo biol. activities were tested by using P388 leukemia and Sarcoma 180 tumor cells. Several of the synthesized compounds exhibited better activity than that of mitomycin C.

Journal of Heterocyclic Chemistry published new progress about 6084-58-8. 6084-58-8 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is O-Isobutylhydroxylamine hydrochloride, and the molecular formula is C4H12ClNO, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ihantola, Tuukka published the artcileGenotoxic and inflammatory effects of spruce and brown coal briquettes combustion aerosols on lung cells at the air-liquid interface, Safety of Coronene, the publication is Science of the Total Environment (2022), 806(Part_1), 150489, database is CAplus and MEDLINE.

Solid fuel usage in residential heating and cooking is one of the largest sources of ambient and indoor air particulate matter, which causes adverse effects on the health of millions of peoples worldwide. Emissions from solid fuel combustion, such as biomass or coal, are detrimental to health, but toxicol. responses are largely unknown. In the present study, we compared the toxicol. responses regarding cytotoxicity, inflammation and genotoxicity of spruce (SPR) and brown coal briquette (BCB) combustion aerosols on human alveolar epithelial cells (A549) as well as a coculture of A549 and differentiated human monocytic cells (THP-1) into macrophages exposed at the air-liquid interface (ALI). We included both the high emissions from the first hour and moderate emissions from the third hour of the batch combustion experiment in one ALI system, whereas, in the second ALI system, we exposed the cells during the whole 4-h combustion experiment, including all combustion phases. Physico-chem. properties of the combustion aerosol were analyzed both online and offline. Both SPR and BCB combustion aerosols caused mild cytotoxic but notable genotoxic effects in co-cultured A549 cells after one-hour exposure. Inflammatory response anal. revealed BCB combustion aerosols to cause a mild increase in CXCL1 and CXCL8 levels, but in the case of SPR combustion aerosol, a decrease compared to control was observed

Science of the Total Environment published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Safety of Coronene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hamacher, K. published the artcileElectrochemical cell for separation of [¹⁸F]fluoride from irradiated ¹⁸O-water and subsequent no carrier added nucleophilic fluorination, Category: catalysis-chemistry, the publication is Applied Radiation and Isotopes (2002), 56(3), 519-523, database is CAplus and MEDLINE.

An electrochem. cell was designed allowing the anodic deposition of n.c.a. [¹⁸F]fluoride solubilized in an ¹⁸O-water target and subsequent n.c.a. nucleophilic ¹⁸F-fluorination. The recovery of the deposited [¹⁸F]fluoride can be achieved in the presence of an aprotic solvent containing a phase-transfer catalyst (PTC). The radioisotope adsorbed electrochem. at the cylindrical surface of a glassy carbon electrode can be dried easily by washing the cell twice with dry aprotic solvents while maintaining a low elec. field. This simple washing step makes an azeotropic drying process obsolete. Accordingly, less basic cryptates like [K?2.2.2.]oxalate or triflate can be used for nucleophilic ¹⁸F-fluorination because loss of activity as a consequence of azeotropic drying under conditions of low basicity does not occur. The usefulness of this technique is exemplified for the n.c.a. synthesis of various ¹⁸F-labeled compounds The radiotracers were synthesized with higher radiochem. yields and under much easier conditions than the conventional ¹⁸F-fluorination procedure which includes an addnl. drying step of the PTC.

Applied Radiation and Isotopes published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Saito, Kaori published the artcileCalix[4]arenes bearing four redox-active ¦Ð-conjugated pendant groups for a dimensionally oriented redox system, Quality Control of 1798-04-5, the publication is Bulletin of the Chemical Society of Japan (2002), 75(8), 1845-1846, database is CAplus.

A p-tert-butylcalix[4]arene I [R = CH₂CONH(p-C₆H₄NH)₃Ac], bearing four redox-active phenylenediamine pendant groups on the lower rim, was synthesized and characterized spectroscopically and electrochem. The interconversion of the oxidation states of the pendant groups was demonstrated both chem. and electrochem.

Bulletin of the Chemical Society of Japan published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Quality Control of 1798-04-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Takahashi, Eiki published the artcileDiscovery of potent transient receptor potential vanilloid 1 antagonists: Design and synthesis of phenoxyacetamide derivatives, Name: 2-(4-(tert-Butyl)phenoxy)acetic acid, the publication is Bioorganic & Medicinal Chemistry Letters (2013), 23(11), 3154-3156, database is CAplus and MEDLINE.

We aimed to discover a novel type of transient receptor potential vanilloid 1 (TRPV1) antagonist because such antagonists are possible drug candidates for treating various disorders. We modified the structure of hit compound I (human TRPV1 IC₅₀ = 411 nM) and converted its pyrrolidino group to a (hydroxyethyl)methylamino group, which substantially improved inhibitory activity (II; human TRPV1 IC₅₀ = 33 nM). In addition, II ameliorated bladder overactivity in rats in vivo.

Bioorganic & Medicinal Chemistry Letters published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C14H31NO2, Name: 2-(4-(tert-Butyl)phenoxy)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Takahashi, Eiki published the artcileDiscovery of potent transient receptor potential vanilloid 1 antagonists: Design and synthesis of phenoxyacetamide derivatives, Application of 2-(4-(Trifluoromethyl)phenoxy)acetic acid, the publication is Bioorganic & Medicinal Chemistry Letters (2013), 23(11), 3154-3156, database is CAplus and MEDLINE.

We aimed to discover a novel type of transient receptor potential vanilloid 1 (TRPV1) antagonist because such antagonists are possible drug candidates for treating various disorders. We modified the structure of hit compound I (human TRPV1 IC₅₀ = 411 nM) and converted its pyrrolidino group to a (hydroxyethyl)methylamino group, which substantially improved inhibitory activity (II; human TRPV1 IC₅₀ = 33 nM). In addition, II ameliorated bladder overactivity in rats in vivo.

Bioorganic & Medicinal Chemistry Letters published new progress about 163839-73-4. 163839-73-4 belongs to catalysis-chemistry, auxiliary class Trifluoromethyl,Fluoride,Carboxylic acid,Benzene,Ether, name is 2-(4-(Trifluoromethyl)phenoxy)acetic acid, and the molecular formula is C8H6ClNO3S2, Application of 2-(4-(Trifluoromethyl)phenoxy)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bock, Harald published the artcileStructure of bis(pentafluorophenyl)xenon, Xe(C₆F₅)₂, Synthetic Route of 1206-46-8, the publication is Angewandte Chemie, International Edition (2002), 41(3), 448-450, database is CAplus and MEDLINE.

Reaction of Me₃SiC₆F₅ with XeF₂ in CH₂Cl₂ gave Xe(C₆F₅)₂ (1). The x-ray crystal structure of 1 was determined The exptl. results are supported by MP2 and DFT (B3LYP) calculations

Angewandte Chemie, International Edition published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Synthetic Route of 1206-46-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Monte, Manuel J. S. published the artcileVapor pressures, enthalpies and entropies of sublimation of trans-cinnamic acid and of nine methoxy and dimethoxycinnamic acids, HPLC of Formula: 16909-09-4, the publication is Journal of Chemical Thermodynamics (1999), 31(11), 1443-1456, database is CAplus.

The Knudsen mass-loss effusion technique was used to measure the vapor pressure as a function of temperature for trans-cinnamic acid and nine substituted methoxy and dimethoxy cinnamic acids. From the temperature dependence of the vapor pressure, the standard molar enthalpies and entropies of sublimation at 298.15 K were calculated for all the studied compounds using the estimated value ¦¤_cr^gc_p,m^o = -50 J¡¤K^-1¡¤mol^-1. The results obtained for trans-cinnamic acid and for the trans-methoxy and trans-dimethoxy cinnamic acids together with literature results for benzoic acid and substituted methoxy and dimethoxy benzoic acids allowed us to derive the correlation: ¦¤_cr^gH_m^o{T(p = 0.5 Pa)}/(kJ¡¤mol^-1) = (0.623 ¡À 0.026)¡¤{T(p = 0.5 Pa)/K} + (-106.3 ¡À 9.4) where T(p = 0.5 Pa) is the temperature at which the equilibrium vapor pressure of each crystalline compound is 0.5 Pa. (c) 1999 Academic Press.

Journal of Chemical Thermodynamics published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, HPLC of Formula: 16909-09-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nakamoto, Masami published the artcilePreparation and crystal structures of gold(I) complexes of a series of benzenethiolates: pair formation by gold-to-gold interactions of (benzenethiolato)(triphenylphosphine)gold(I), Application In Synthesis of 22693-41-0, the publication is Chemische Berichte (1993), 126(3), 605-10, database is CAplus.

Ph₃PAuCl reacts readily with PhSH and sterically hindered 2,4,6-R₃C₆H₂SH in the presence of NEt₃ to yield stable Ph₃PAu(SC₆H₂R₃-2,4,6) (1–4; R = H, Me, Et, CHMe₂, resp.). The crystal structures of these complexes were determined by single-crystal x-ray diffraction anal. In all compounds the Au atoms are linearly 2-coordinate with very similar bond lengths and angles. While 2–4 with bulky thiolate ligands are monomeric in the crystal lattice, 1 forms pairs of mols. with intermol. Au-Au contacts of 313.5(5) pm. The Moessbauer spectra of the complexes exhibit large isomer shifts (I.S.), of 3.06¡ú3.72 mm s^-1, and quadrupole splittings (Q.S.), of 7.90¡ú8.68 mm s^-1. These data can be attributed to the strong electron-donating properties of the benzenethiolate ligands. The Au-Au contacts in 1 lead to I.S. and Q.S. values which are slightly smaller than those of 2–4. The Au-S distances do not show a major influence of the S-Au-P pairing in 1 as compared to 2–4.

Chemische Berichte published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Application In Synthesis of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia