Month: November 2022

Shahidi, Fereidoon published the artcilePartial molar volumes of organic compounds in water. VI. ¦Á,¦Ø-Diaminoalkane hydrochlorides, Recommanded Product: Propane-1,3-diamine dihydrochloride, the publication is Journal of Solution Chemistry (1978), 7(7), 549-59, database is CAplus.

Measurements of the partial molar volumes in H₂O at 25¡ã of the mono- and dihydrochlorides of the ¦Á,¦Ø-diaminoalkanes, up to a chain length of 10 C atoms, are reported. Volumes of ionization were determined and the electrostriction of the solvent calculated Effects of the substituents are felt up to the ¦Ã-C atom, but thereafter are only very weak or nonexistent.

Journal of Solution Chemistry published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C24H12, Recommanded Product: Propane-1,3-diamine dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Dixon, David A. published the artcileStructural studies of tris(dialkylamino)sulfonium (TAS) fluorosilicates, Quality Control of 312-40-3, the publication is Heteroatom Chemistry (1993), 4(2-3), 287-95, database is CAplus.

The crystal structures of two pentavalent silicon anions are discussed. The structure of [SiMe₃F₂]^–?1 shows a trigonal bipyramidal structure with the fluorines in apical positions. The Si-F bond distances are the longest known of this type. The crystal structure of fluorosilicate 2 (1,1-diphenyl-1-fluoro-3,3-bis[trifluoromethyl]-1,3-dihydro-2,1-benzoxasilole[ion 1-]) is distorted toward a rectangular structure along the Berry pseudorotation coordinate. The lone Si-F bond distance in 2 is much shorter than that in 1. The ab initio calculations on a variety of pentavalent fluorinated silicon anions are reported, and good agreement with the exptl. data are found. Fluoride affinities for the fluorosilanes are reported and are in reasonable agreement with the exptl. values where known. The fluoride affinity of the tetra-coordinated species is related to the length of the Si-F bond in the pentavalent anion.

Heteroatom Chemistry published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C12H10F2Si, Quality Control of 312-40-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jackels, Susan C. published the artcileTetragonal cobalt(III) complexes containing tetradentate macrocyclic amine ligands with different degrees of unsaturation, Safety of Propane-1,3-diamine dihydrochloride, the publication is Inorganic Chemistry (1972), 11(12), 2893-901, database is CAplus.

The syntheses, structures, and properties of trans-[Co(TIM)X2]Z, trans-[Co(DIM)X2]Z and trans-Co(DMC)X2]Z (TIM = I; DIM = II; DMC = III; X halide or NO2; Z = halide, ClO4-, or PF6-) were reported. Infrared and PMR spectral studies provided proof of the structures of the macrocyclic ligands in these compounds and the latter gave insight into stereochem. relations among these complexes. Spectrochem. studies revealed that the ligand field strengths of the macro-cycles increased as the degree of unsaturation of the ligand increases. Comparisons with other macrocycles showed the relative effect on ligand field strengths of such groups as -N(H)-, N:c, -N:C-C:N-, and pyridine. Voltammetric data showed that the lower oxidation states of Co are stabilized by greater degrees of ligand unsaturation

Inorganic Chemistry published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Safety of Propane-1,3-diamine dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Katz, Michael G. published the artcileMolecular cardiac surgery with recirculating delivery (MCARD): procedure and vector transfer, Quality Control of 140-28-3, the publication is Methods in Molecular Biology (New York, NY, United States) (2017), 271-289, database is CAplus and MEDLINE.

Despite progress in clin. treatment, cardiovascular diseases are still the leading cause of morbidity and mortality worldwide. Therefore, novel therapeutic approaches are needed, targeting the underlying mol. mechanisms of disease with improved outcomes for patients. Gene therapy is one of the most promising fields for the development of new treatments for the advanced stages of cardiovascular diseases. The establishment of clin. relevant methods of gene transfer remains one of the principal limitations on the effectiveness of gene therapy. Recently, there have been significant advances in direct and transvascular gene delivery methods. The ideal gene transfer method should be explored in clin. relevant large animal models of heart disease to evaluate the roles of specific mol. pathways in disease pathogenesis. Characteristics of the optimal technique for gene delivery include low morbidity, an increased myocardial transcapillary gradient, esxtended vector residence time in the myocytes, and the exclusion of residual vector from the systemic circulation after delivery to minimize collateral expression and immune response. Here we describe myocardial gene transfer techniques with mol. cardiac surgery with recirculating delivery in a large animal model of post ischemic heart failure.

Methods in Molecular Biology (New York, NY, United States) published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Quality Control of 140-28-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ashouri, Fatemeh published the artcileFabrication, characterization and structure activity relationship of Co and Mn encapsulated on magnetic nanocomposite and its application in one-pot tandem synthesis of various tetrazoles and vitamin K₃, Quality Control of 13822-56-5, the publication is Chemical Papers (2022), 76(6), 3581-3605, database is CAplus.

Considering the importance of vitamin K₃ in com. pet foods, veterinary medicines, poultry, and some swine feed and also tetrazole derivatives in drugstore, medicine, chem., petroleum, and military industry, design efficient catalytic systems are desirable. Herein, four magnetic nanocomposites (MNCs) of cobalt and manganese using metformin, 3-aminopropyltrimethoxysilane (L1) and 2-aminoethyl-3-aminopropyltrimethoxysilane (L2) were designed and constructed as an efficient and controllable catalytic system. The synthesized nanocomposites fully characterized by FT-IR, AAS, ICP-OES, BET, CHN elemental anal., SEM, TEM, DLS, EDX, TGA, VSM, and XPS spectroscopy. The well-prepared magnetically recoverable nanocomposites were used in the synthesis of a wide derivatives of ¦Á-hydrazino tetrazoles (¦Á-HyT), ferrocenyltetrazoles (FcT), arylaminotetrazoles (ArAT) and also vitamin K₃. Besides, the effect of operating parameters, such as the amount of catalyst, nature of solvent, temperature and reaction time, metal nature, chain length and hydrophobicity properties of linkers, was studied in the catalytic efficiency of synthesized nanocatalysts. The best catalytic results were obtained in the following order: FS-L2-Met@Co(II) > FS-L2-Met@Mn(II) > FS-L1-Met@Co(II) > FS-L1-Met@Mn(II) due to their structural characteristics. In addition to high TOF, these magnetic nanocomposites are superior in easy, inexpensive, and com. preparation, keeping the structural and magnetic characteristics, easy magnetically separation from the reaction medium, short reaction time, mild reaction condition, easy work-up, and reusability without any metal leaching in six runs.

Chemical Papers published new progress about 13822-56-5. 13822-56-5 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is 3-(Trimethoxysilyl)propan-1-amine, and the molecular formula is C6H17NO3Si, Quality Control of 13822-56-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Fenwick, Andrew E. published the artcileSynthesis, Characterization, and Reduction Chemistry of Mixed-Cyclopentadienyl/Arylsulfide Titanium Dichlorides, Quality Control of 22693-41-0, the publication is Organometallics (2003), 22(3), 535-540, database is CAplus.

A series of titanium derivatives [CpTi(SAr)Cl₂] containing both cyclopentadienyl and various substituted arylsulfide ligands (SAr = SC₆H₄Me-4 (1), SC₆H₂Me₃-2,4,6 (2), SC₆H₂Prⁱ₃-2,4,6 (3), SC₆H₂Ph₃-2,4,6 (4)) has been synthesized from the reaction of [CpTiCl₃] with 1 equivalent of the lithium salt of the corresponding aryl sulfides in benzene. X-ray diffraction studies show that each metal center possesses a pseudo-tetrahedral geometry. The compounds undergo one-electron reduction to produce sulfur-bridged dimers of the type [CpTiCl(¦Ì-SAr)]₂ (SAr = SC₆H₂Me₃-2,4,6 (5), SC₆H₂Prⁱ₃-2,4,6 (6)). The solid-state structures of these dimers show that the cyclopentadienyl rings are arranged in a transoid fashion about the [Ti(¦Ì-SAr)₂Ti] core. The Ti-Ti distances, 3.242(1) and 3.225(1) ?, resp., are similar to those found in previously reported Cp/aryloxide dimers with terminal aryloxides and bridging chlorides.

Organometallics published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Quality Control of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hu, Mingyuan published the artcilePolyunsaturated fatty acid intake and incidence of type 2 diabetes in adults: a dose response meta-analysis of cohort studies, Quality Control of 6217-54-5, the publication is Diabetology & Metabolic Syndrome (2022), 14(1), 34, database is CAplus and MEDLINE.

Meta-anal. of relationship between polyunsaturated fatty acid (PUFA) intake and incidence of type 2 diabetes (T2D) in adults. PubMed, Embase, Cochrane Library, and Web of Science databases were searched for cohort studies that examined the association between PUFA and T2D incidence published up to Sept. 6, 2021. Relative risk (RR) or hazard ratio (HR) was used as the effect indicator, each effect size was expressed by 95% confidence interval (CI). The presence of heterogeneity of effect size between studies was assessed by the Q-test and I2 statistics. If I2 ¡Ý 50%, the random-effects model was applied, otherwise the fixed effects model was used. Sensitivity anal. was performed for all models. Potential publication bias was assessed. We conducted linear and nonlinear dose-response meta-analyses, calculated summary relative risk (SRR). Twenty-five articles were selected including 54,000 patients in this study. Our estimates observed no linear associations between total PUFA and the incidence of T2D. However, the summary dose-response curve of T2D risk increased in a nonlinear pattern with the consumption of omega-3 PUFA (Pnonlinearity < 0.001) and docosahexaenoic acid (DHA) (Pnonlinearity = 0.040). Our subgroup anal. showed that total PUFA intake was associated with increased incidence of T2D in Europe (RR: 1.040, 95% CI 1.009 to 1.072), and Australia (RR: 1.188, 95% CI 1.113 to 1.269). However, total PUFA intake was associated with decreased T2D incidence in Asia (RR: 0.897, 95% CI 0.860 to 0.936). Subgroup anal. based on PUFA types showed that DHA intake was associated with decreased T2D incidence (RR: 1.164, 95% CI 1.048 to 1.294) while linoleic acid (LA) decreased T2D incidence (RR: 0.956, 95% CI 0.930 to 0.983). Regarding the sex subgroup, women¡äs intake of total PUFA would increase the risk of T2D (RR: 1.049, 95% CI 1.019 to 1.079) while total PUFA intake decreased the risk of T2D in men (RR: 0.955, 95% CI 0.913 to 0.999). For specific PUFA, dose-response curves show nonlinear significant associations between PUFA intakes and T2D. It may be necessary to pay attention to the effects of PUFA and type of intake on T2D.

Diabetology & Metabolic Syndrome published new progress about 6217-54-5. 6217-54-5 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Aliphatic hydrocarbon chain,Metabolic Enzyme,RAR/RXR,Natural product, name is Docosahexaenoic Acid, and the molecular formula is C22H32O2, Quality Control of 6217-54-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Li, Yuehui published the artcileA General Catalytic Methylation of Amines Using Carbon Dioxide, Product Details of C14H23N, the publication is Angewandte Chemie, International Edition (2013), 52(36), 9568-9571, database is CAplus and MEDLINE.

In this article authors discuss a single Ru complex that is able to convert carbon dioxide and amines into various kinds of N-methylated products. The initial design was motivated by previous reports on the dehydration of primary amides using silanes and the hydrosilylation of carboxylic acid derivatives by us and other groups. Hence, the reaction of carbon dioxide and N-methylaniline in the presence of silanes as a model system was investigated. To identify active catalysts different metal precursors including Ru, Rh, Cu and Fe complexes and phosphine and nitrogen ligands were tested using phenylsilane as reductant.

Angewandte Chemie, International Edition published new progress about 2909-77-5. 2909-77-5 belongs to catalysis-chemistry, auxiliary class Amine,Benzene, name is 2,6-Diisopropyl-N,N-dimethylaniline, and the molecular formula is C14H23N, Product Details of C14H23N.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shie, Jiun-Jie published the artcileInhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic ¦Á,¦Â-unsaturated esters, Computed Properties of 16909-09-4, the publication is Bioorganic & Medicinal Chemistry (2005), 13(17), 5240-5252, database is CAplus and MEDLINE.

The proteolytic processing of polyproteins by the 3CL protease of severe acute respiratory syndrome coronavirus is essential for the viral propagation. A series of tripeptide ¦Á,¦Â-unsaturated esters and ketomethylene isosteres, including AG7088, are synthesized and assayed to target the 3CL protease. Though AG7088 is inactive (IC₅₀ > 100 ¦ÌM), the ketomethylene isosteres and tripeptide ¦Á,¦Â-unsaturated esters containing both P1 and P2 phenylalanine residues show modest inhibitory activity (IC₅₀ = 11-39 ¦ÌM). The Phe-Phe dipeptide inhibitors are designed on the basis of computer modeling of the enzyme-inhibitor complex. The most potent inhibitor (I) with an inhibition constant of 0.52 ¦ÌM is obtained by condensation of the Phe-Phe dipeptide ¦Á,¦Â-unsaturated ester with 4-(dimethylamino)cinnamic acid. The cell-based assays also indicate that I is a nontoxic anti-SARS agent with an EC₅₀ value of 0.18 ¦ÌM.

Bioorganic & Medicinal Chemistry published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C8H6ClN, Computed Properties of 16909-09-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Jingjing published the artcileUltrathin mesoporous NiCo₂O₄ nanosheets as an efficient and reusable catalyst for benzylic oxidation, Application In Synthesis of 457-68-1, the publication is RSC Advances (2015), 5(4), 2405-2410, database is CAplus.

Ultrathin mesoporous NiCo₂O₄ nanosheets as a high efficient and reusable catalyst for benzylic oxidation have been prepared The nanosheets are less than 5 nm in thickness, the pore distribution is in the range of 2-5 nm and the sp. surface area of the nanosheets is about 81.0 m²g^-1. The ultrathin and mesoporous features with high sp. surface area not only provide large amount of binary active sites of Co and Ni, but also improve the contacting ability between the substrate and these active sites, therefore accelerating the rate of reaction and providing high catalytic efficiency for benzylic oxidation The NiCo₂O₄ nanosheets are efficient heterogeneous catalyst in the oxidation of 4,4′-difluorodiphenylmethane into 4,4′-difluorobenzophenone with a yield of 99%. Furthermore, the NiCo₂O₄ nanosheets catalyst exhibits general applicability, convenient separability and good stability in the benzylic oxidation

RSC Advances published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C6H13NO2, Application In Synthesis of 457-68-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia