Month: November 2022

Wang, Yilin published the artcileCatalytic membrane nano reactor with Cu/ZnO in situ immobilized in membrane pores for methanol dehydrogenation to formaldehyde, Category: catalysis-chemistry, the publication is Journal of Membrane Science (2022), 120014, database is CAplus.

A catalytic membrane nano reactor (CMNR) with deep-permeation nanocomposite structure (DPNS) was fabricated by flowing synthesis for methanol dehydrogenation to formaldehyde. In this structure, Cu/ZnO nanoparticles are in situ immobilized in the pores of Ti membrane substrate with thickness 1 mm, pore size 10¦Ìm, and porosity 45%. The characterization by XRD, TGA, XPS, SEM and TEM indicates that the Cu/ZnO nanoparticles with mean size of 82 nm was successfully embedded into the membrane pores, and well distributed along the thickness direction of the membrane. The ICP measurement results demonstrate that the immobilization amount of 20 mg of Cu/ZnO nanoparticles per g of Ti membrane substrate can be obtained. The prepared Cu/ZnO/Ti CMNR was built in the technol. apparatus for catalytic dehydrogenation of methanol. For one sheet of membrane setting up, the conversion efficiency of methanol 7.5%, the mass specific activity 183 mmol_MeOH¡¤h^-1¡¤g^-1_cat, the pressure drop 2.7 kPa with gas permeating the membrane was measured, under mass ratio of Cu to ZnO 0.05 in the membrane, reaction temperature 360¡ã, the gas flux 8 m³.m^-2.h^-1 through the membrane. The selectivity of formaldehyde is ¡Ü 98% and increases with increasing reaction temperature, the highest mass specific activity of 318 mmol_MeOH.h^-1.g^-1_cat can be achieved with mass ratio of Cu to ZnO 0.12 at 360¡ã. For three sheets of CMNRs setting up in serials, > 18% of conversion efficiency has been achieved with gas pressure drop 6.8 kPa. If 70 sheets of CMNRs are packed in serials to build a reactor with 70 mm thickness, which will produce the gas pressure drop 162 kPa, the conversion efficiency of 99% would be expected according to a simple simulation based on the exptl. measurement.

Journal of Membrane Science published new progress about 13822-56-5. 13822-56-5 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is 3-(Trimethoxysilyl)propan-1-amine, and the molecular formula is C10H15ClO3S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Weng, Jian-Quan published the artcileEnantioselective Friedel-Crafts Alkylation Reactions of 3-Substituted Indoles with Electron-Deficient Alkenes, Synthetic Route of 4230-93-7, the publication is Journal of Organic Chemistry (2016), 81(7), 3023-3030, database is CAplus and MEDLINE.

Highly enantioselective Friedel-Crafts C2-alkylation reactions of 3-substituted indoles with ¦Á,¦Â-unsaturated esters and nitroalkenes were developed using chiral Lewis acids as catalysts, which afforded chiral indole derivatives bearing C2-benzylic stereogenic centers in good to excellent yields (up to 99%) and enantioselectivities (up to 96% ee).

Journal of Organic Chemistry published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H10CoF6P, Synthetic Route of 4230-93-7.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Li, Xiaoman published the artcileCatalyst- and Metal-Free Photo-Oxidative Coupling of Thiols with BrCCl₃, Category: catalysis-chemistry, the publication is European Journal of Organic Chemistry (2022), 2022(23), e202200340, database is CAplus.

This paper reported a catalyst- and metal-free method to construct disulfide bond with BrCCl₃ under light irradiation This clean and mild reaction promoted the oxidative coupling of thiols with wide substrate scope, and was applicable to benzylic, aryl and aliphatic thiols, especially cysteine derivative The disulfides were obtained in high yields up to 98%, avoiding the use of heating, strong oxidant, metal reagent or catalyst. This facile strategy facilitated the synthesis of disulfide compounds

European Journal of Organic Chemistry published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C14H10O4S2, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jiang, Hejin published the artcileChiral nanostructures self-assembled from nitrocinnamic amide amphiphiles: substituent and solvent effects, Product Details of C9H7NO4, the publication is Beilstein Journal of Nanotechnology (2019), 1608-1617, database is CAplus and MEDLINE.

Chiral nanostructures, such as a-helical proteins and double helix DNA, are widely found in biol. systems and play a significant role in the biofunction of life. These structures are essentially fabricated through the covalent or noncovalent bonds between small chiral mols. It is thus an important issue to understand how small chiral mols. can form chiral nanostructures. Here, using a series of isomeric nitrocinnamic amide derivatives, we have investigated the self-assembly behavior and the effect of the substituent position as well as the solvent on the formation of chiral nanostructures. It was found that totally different chiral nanostructures were formed due to the different positions of the nitro group on the cinnamic amide. Moreover, it was found that the chiral sense of the self-assembled nanostructures can be regulated by the solvent whereby helicity inversion was observed This work provides a simple way to regulate the self-assembly pathway via mol. design and choice of solvent for the controlled creation of chiral nanostructures.

Beilstein Journal of Nanotechnology published new progress about 1772-76-5. 1772-76-5 belongs to catalysis-chemistry, auxiliary class Benzenes, name is (E)-3-(3-Nitrophenyl)acrylic acid, and the molecular formula is C9H7NO4, Product Details of C9H7NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yang, Wenqian published the artcileThe First Fluorescent Diboronic Acid Sensor Specific for Hepatocellular Carcinoma Cells Expressing Sialyl Lewis X, Synthetic Route of 5411-14-3, the publication is Chemistry & Biology (2004), 11(4), 439-448, database is CAplus and MEDLINE.

Carbohydrate antigens with subterminal fucosylation have been implicated in the development and progression of several cancers, including hepatocellular carcinoma (HCC). Fluorescent sensors targeting fucosylated carbohydrate antigens could potentially be used for diagnostic and other applications. The authors have designed and synthesized a series of 26 diboronic acid compounds as potential fluorescent sensors for such carbohydrates. Among these compounds, 7q was able to fluorescently label cells expressing high levels of sLex (HEPG2) within a concentration range of 0.5 to 10 ¦ÌM. This compound (7q) did not label cells expressing Lewis Y (HEP3B), nor cells without fucosylated antigens (COS7). This represents the first example of a fluorescent compound labeling cells based on cell surface carbohydrate structures.

Chemistry & Biology published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C17H14F3N3O2S, Synthetic Route of 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhang, Long published the artcileDiscovery of a potent dual EGFR/HER-2 inhibitor L-2 (selatinib) for the treatment of cancer, Computed Properties of 6950-53-4, the publication is European Journal of Medicinal Chemistry (2013), 833-841, database is CAplus and MEDLINE.

To develop potent dual EGFR/HER-2 inhibitors with improved druggability, a series of new lapatinib analogs were designed and synthesized. Compared with lapatinib, L-2, 6-(5-((2-(Sulfamoyl)ethylamino)methyl)furan-2-yl)-N-(4-(3-fluorobenzyloxy)-3-chlorophenyl) quinazolin-4-amine (L-4) and 1-(4-((5-(4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino) quinazolin-6-yl)furan-2-yl)methyl)piperazin-1-yl)ethanone (M-6) were more active against BT-474 or NCI-N87 cells. In vivo efficacy studies indicated that L-2 significantly suppressed tumor growth in NCI-N87 (94.8% inhibition) or SK-OV-3 xenograft (85.7% inhibition) without causing significant loss of body weight And the inhibition rates of lapatinib in the two xenograft models were 89.7% and 78.8%, resp. Moreover, further studies revealed that the potent in vivo activities of L-2 may be mainly attributed to its superior aqueous solubility and oral bioavailability. In addition, a high-yielding one-pot procedure was developed for the synthesis of lapatinib and its analogs.

European Journal of Medicinal Chemistry published new progress about 6950-53-4. 6950-53-4 belongs to catalysis-chemistry, auxiliary class Salt,sulfides,Amine,Aliphatic hydrocarbon chain, name is 2-(Methylthio)ethanamine hydrochloride, and the molecular formula is C13H19Br2ClN2O, Computed Properties of 6950-53-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Esguerra, Kenneth Virgel N. published the artcileCatalytic aerobic oxidation of halogenated phenols, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine, the publication is Inorganica Chimica Acta (2018), 197-200, database is CAplus.

Phenol pollutants such as halophenols and guaiacol derivatives are produced as byproducts of many industrial processes. Aerobic oxidations for their degradation in the context of effluent treatment or environmental remediation often lack selectivity. This work describes a copper (Cu)-catalyzed approach that converts three equivalent of halogenated phenols into a single ortho-quinone, at the expense of reducing dioxygen (O₂) to water (H₂O).

Inorganica Chimica Acta published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Makai, Szabolcs published the artcilePreparation of O-pivaloyl hydroxylamine triflic acid, Recommanded Product: O-Pivaloylhydroxylamine trifluoromethanesulfonate, the publication is Organic Syntheses (2020), 207-216, database is CAplus.

The detailed two-step preparation of O-pivaloyl hydroxylamine triflic acid was reported (I). Use of I as a reagent, for example in the synthesis of N-heterocycles and as an aminating agent, was also discussed.

Organic Syntheses published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Recommanded Product: O-Pivaloylhydroxylamine trifluoromethanesulfonate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Makai, Szabolcs published the artcileDirect Synthesis of Unprotected 2-Azidoamines from Alkenes via an Iron-Catalyzed Difunctionalization Reaction, Category: catalysis-chemistry, the publication is Journal of the American Chemical Society (2020), 142(51), 21548-21555, database is CAplus and MEDLINE.

Unprotected, primary 2-azidoamines are versatile precursors to vicinal diamines, which are among the most common motifs in biol. active compounds Herein, we report their operationally simple synthesis through an iron-catalyzed difunctionalization of alkenes. A wide array of alkene substrates are tolerated, including complex drug-like mols. and a tripeptide. Facile derivatizations of the azidoamine group demonstrate the versatility of this masked diamine motif in chemoselective, orthogonal transformations. Applications of the methodol. in the concise synthesis of RO 20-1724 as well as in the formal total syntheses of both (¡À)-hamacanthin B and (¡À)-quinagolide further demonstrate the broad synthetic potential of this highly functional-group-tolerant reaction.

Journal of the American Chemical Society published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Fitilis, I. published the artcileTwo-photon polymerization of a diacrylate using fluorene photoinitiators-sensitizers, Synthetic Route of 2909-77-5, the publication is Journal of Photochemistry and Photobiology, A: Chemistry (2010), 215(1), 25-30, database is CAplus.

Two-photon polymerization (TPP) of a diacrylate (monomer) using 2 different fluorene mols. as photoinitiators-sensitizers is reported. The fluorene mols. contain e^– donating (triphenylamine) or e^– withdrawing (phthalimide) edge substituents. An amine co-initiator is also used lowering the polymerization threshold. The dependence of the polymerization properties (threshold, polymerization rate, lateral and axial resolution) on the type of resin, the writing power and speed as well as on the NA of the focusing lens is studied. The fluorene with triphenylamine substituent exhibits favorable properties as TPP photoinitiator-sensitizer compared to the fluorene with phthalimide, although its 2-photon absorption cross-section is smaller. Polymerization of the pure monomer or monomer-amine composite (i.e. without fluorene) is also reported.

Journal of Photochemistry and Photobiology, A: Chemistry published new progress about 2909-77-5. 2909-77-5 belongs to catalysis-chemistry, auxiliary class Amine,Benzene, name is 2,6-Diisopropyl-N,N-dimethylaniline, and the molecular formula is C14H23N, Synthetic Route of 2909-77-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia