Month: December 2022

Jackl, Moritz K. published the artcileContinuous Flow Synthesis of Morpholines and Oxazepanes with Silicon Amine Protocol (SLAP) Reagents and Lewis Acid Facilitated Photoredox Catalysis, Application In Synthesis of 1293990-73-4, the publication is Organic Letters (2017), 19(17), 4696-4699, database is CAplus and MEDLINE.

Photocatalytic coupling of aldehydes and silicon amine protocol (SLAP) reagents enables the simple, scalable synthesis of substituted morpholines, e.g., I (X-rays single crystal structure shown), oxazepanes, thiomorpholines, and thiazepanes under continuous flow conditions. Key to the success of this process is the combination of an inexpensive organic photocatalyst (TPP) and a Lewis acid additive, which form an amine radical cation that is easily reduced to complete the catalytic cycle. Di- and trisubstituted SLAP reagents are formed in one step by an iron-catalyzed aminoetherification of olefins.

Organic Letters published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Application In Synthesis of 1293990-73-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Gawryszewska, P. published the artcileInfluence of charge-transfer state on luminescence properties of Eu(III) complex with o-phenylenedioxydicarboxylic acid, Formula: C10H10O6, the publication is Journal of Luminescence (2007), 496-499, database is CAplus.

Na[Eu(C₁₀H₈O₆)₂(H₂O)₂].4H₂O (C₁₀H₈O₆ = 1,2-benzenedioxydiacetato) was synthesized. Absorption, emission, and excitation spectra at 293, 77 and 4 K as well as the luminescence decay time measurements were applied to characterize the photophys. properties of the crystals. Strong temperature dependence of the luminescence decay time suggests that the ligand-to-metal charge-transfer state of Eu(III) deactivates the ligand excited state so that the energy transfer from ligand triplet state to metal ion levels does not occur. A correlation between spectroscopic properties of the complex in solid state and in solutions was made. The study for different pH values and various metal:ligand molar ratios showed the existence of >1 form of the complex where ML and ML₂ forms dominated.

Journal of Luminescence published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Formula: C10H10O6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Gortner, Willis A. published the artcileRelation of chemical structure to plant growth-regulator activity in the pineapple plant. V. Post-harvest delay of senescence of pineapple fruit, Name: 2-(4-(tert-Butyl)phenoxy)acetic acid, the publication is Botanical Gazette (Chicago) (1969), 130(2), 87-97, database is CAplus.

The effects of 369 compounds, including 94 phenoxyacetic acids, 43 other phenoxy acids, 23 phenylacetic acids, 15 hydrocinnamic acids, 9 benzoic acids, 7 salicylic acids, 48 naphthalene derivatives, 22 indole acids, 5 hydrazine derivatives, and 8 cinnamic acids, for postharvest delay of senescence of pineapple fruit (Ananas comosus) were determined Seventy-six of the compounds were active, and 27 were highly active in delaying senescence. In the phenoxyacetic acid series, high activity was obtained from some halogen-substituted acids but not generally from Me-substituted acids. In the phenoxy-¦Á-propionic acid series, high activity was not observed for a number of halogen- and Me-substituted acids. None of the substituted phenoxy acids other than HOAc and ¦Á- propionic showed even moderate activity. An appreciable number of Cl-substituted phenylacetic acids and several benzoic acids showed activity. None of the phenylalkylcarboxylic acids other than HOAc showed even moderate activity. None of the salicylic acid, phthalic acids, or phthalamic acids showed any activity. All hydrazine derivatives were inactive.

Botanical Gazette (Chicago) published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Name: 2-(4-(tert-Butyl)phenoxy)acetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zoh, Dyung Duk published the artcileCooperation of ¦Â-cyclodextrin with macrocyclic metal centers in the action of artificial metalloesterases built on poly(ethylenimine), Computed Properties of 1798-04-5, the publication is Bioorganic Chemistry (1994), 22(3), 242-52, database is CAplus.

¦Â-Cyclodextrin (CD) was attached to poly(ethylenimine) (PEI), and then macrocyclic metal centers were constructed on the polymer by condensation with glyoxal or butanedione in the presence of metal (Zn^II, Ni^II, or Co^II) templates. The resulting polymers were treated with acetic anhydride to block primary or secondary amines. Hydrolysis of 2 nitrophenyl esters containing t-butylphenyl residues in the acyl moieties was catalyzed by the PEI derivatives containing both CD cavities and macrocyclic metal centers. Anal. of the kinetic data indicated that the CD cavities and the metal centers provided binding sites and catalytic sites, resp., for the ester substrates, mimicking metalloesterases. Although the content of the metal center was much smaller for the Zn^II-containing artificial enzyme compared with the Ni^II and Co^II analogs, catalytic efficiency was greater for the Zn^II derivative Kinetic data indicate high reactivity of the metal center in the productive complex formed between the catalyst and the substrate, when the unproductive binding by the CD cavities is considered.

Bioorganic Chemistry published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C5H10N2OS, Computed Properties of 1798-04-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lee, Hyo Won published the artcileSequential Post-Polymerization Modification of Aldehyde Polymers to Ketone and Oxime Polymers, Recommanded Product: O-Isobutylhydroxylamine hydrochloride, the publication is Macromolecular Rapid Communications (2021), 42(22), 2100478, database is CAplus and MEDLINE.

A new sequential post-polymerization modification route has been developed for the synthesis of multifunctional polymers from a simple aldehyde polymer. In the first modification step, a template polymer derived from the radical polymerization of 4-vinylbenzaldehyde undergoes Rh-catalyzed hydroacylation with alkenes to furnish a group of ketone polymers. In the second modification step, Schiff base formation with alkoxy ammonium salts introduces a second group-an oxime functionality. Both the steps are highly efficient, introducing evenly distributed dual functionalities at the same position.

Macromolecular Rapid Communications published new progress about 6084-58-8. 6084-58-8 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is O-Isobutylhydroxylamine hydrochloride, and the molecular formula is C4H12ClNO, Recommanded Product: O-Isobutylhydroxylamine hydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jung, Byung Jun published the artcileAir-Operable, High-Mobility Organic Transistors with Semifluorinated Side Chains and Unsubstituted Naphthalenetetracarboxylic Diimide Cores: high Mobility and Environmental and Bias Stress Stability from the Perfluorooctylpropyl Side Chain, Name: 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecan-1-amine, the publication is Advanced Functional Materials (2010), 20(17), 2930-2944, database is CAplus.

N,N’-bis(3-(perfluoroctyl)propyl)-1,4,5,8-naphthalenetetracarboxylic acid diimide (8-3-NTCDI) was newly synthesized, as were related fluorooctylalkyl-NTCDIs and alkyl-NTCDIs. The 8-3-NTCDI-based organic thin-film transistor (OTFT) on an octadecyltrimethoxysilane (OTS)-treated Si/SiO₂ substrate shows apparent electron mobility approaching 0.7 cm² V^-1s^-1 in air. The fluorooctylethyl-NTCDI (8-2-NTCDI) and fluorooctylbutyl-NTCDI (8-4-NTCDI) had significantly inferior properties even though their chem. structures are only slightly different, and nonfluorinated decyl and undecyl NTCDIs did not operate predictably in air. From at. force microscopy, the 8-3-NTCDI active layer deposited with the substrate at 120¡ã forms a polycrystalline film with grain sizes >4¦Ìm. Mobilities were stable in air for one week. After 100 days in air, the average mobility of three OTFTs decreased from 0.62 to 0.12 cm² V^-1s^-1, but stabilized thereafter. The threshold voltage (V_T) increased by 15 V in air, but only by 3 V under nitrogen, after one week. On/off ratios were stable in air throughout. The authors also studied transistor stability to gate bias stress. The transistor on hexamethlydisilazane (HMDS) is more stable than that on OTS with mobility comparable to amorphous Si TFTs. V_T shifts caused by ON (30 V) and OFF (-20 V) gate bias stress for the HMDS samples for 1 h were 1.79 V and 1.27 V under N₂, resp., and relaxation times of 10⁶ and 10⁷ s were obtained using the stretched exponential model. These performances are promising for use in transparent display backplanes.

Advanced Functional Materials published new progress about 30670-30-5. 30670-30-5 belongs to catalysis-chemistry, auxiliary class Polyfluoroalkanes, name is 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecan-1-amine, and the molecular formula is C10H6F17N, Name: 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecan-1-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ohshita, Joji published the artcileSynthesis of Siloles Condensed with Benzothiophene and Indole Rings, Name: Difluorodiphenylsilane, the publication is Organometallics (2004), 23(23), 5622-5625, database is CAplus.

Compounds having a silole ring condensed with benzothiophene and N-methylindole units (BBTS and BMIS; shown as I and II) were prepared The electronic states of BBTS and BMIS were examined with respect to their UV and emission spectra and CV measurements, in comparison with those of bibenzothiophene and bi-N-methylindole, indicating that the existence of the silole ring in BBTS and BMIS affects the electronic states to decrease the HOMO-LUMO energy gaps. The results of MO calculations on model compounds agree well with the exptl. observations. The crystal and mol. structures of II were determined by x-ray crystallog. Electroluminescence devices based on I and II performed poorly.

Organometallics published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C12H10F2Si, Name: Difluorodiphenylsilane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Pearson, Anthony J. published the artcileSome Studies on the Uses of 2-Bromoethyl and 2-Iodoethyl Ester Blocking Groups in Peptide Synthesis: Samarium Diiodide-Mediated Deprotection, Computed Properties of 1860-58-8, the publication is Journal of Organic Chemistry (1994), 59(8), 2257-60, database is CAplus.

Deprotection of 2-bromoethyl esters during peptide synthesis is often problematic, owing to competing formation of 2-hydroxyethyl esters. A simple and reproducible method is described for the removal of the 2-bromoethyl group via conversion to the corresponding 2-iodoethyl ester, followed by deprotection of the latter by treatment with samarium diiodide under anhydrous oxygen-free conditions. No racemization was observed for phenylglycine derivatives during the protection/halide exchange/deprotection sequence. Application of this methodol. to a number of peptides as well as simple carboxylate derivatives is described.

Journal of Organic Chemistry published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, Computed Properties of 1860-58-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lee, Jeewoo published the artcile2-Benzyl and 2-phenyl-3-hydroxypropyl pivalates as protein kinase C ligands, SDS of cas: 1860-58-8, the publication is Bioorganic & Medicinal Chemistry (2006), 14(6), 2022-2031, database is CAplus and MEDLINE.

A series of 2-benzyl and 2-phenyl-3-hydroxypropyl pivalates designed to incorporate the principal pharmacophores of phorbol esters have been synthesized and tested as PKC-¦Á ligands. Among the analogs, I exhibited the most potent binding affinity with a K_i = 0.7 ¦ÌM. The synthesized analogs were subjected to mol. modeling anal. based on two alternative models of the phorbol pharmacophore and a docking study of I was carried out.

Bioorganic & Medicinal Chemistry published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, SDS of cas: 1860-58-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lee, Kyeong published the artcile(Aryloxyacetylamino)benzoic Acid Analogues: A New Class of Hypoxia-Inducible Factor-1 Inhibitors, Formula: C12H16O3, the publication is Journal of Medicinal Chemistry (2007), 50(7), 1675-1684, database is CAplus and MEDLINE.

Structural modification of a compound discovered during screening using an HRE-dependent reporter assay has revealed a novel class of HIF-1 inhibitors, which potently inhibit the HIF-1¦Á protein accumulation and its target gene expression under hypoxic conditions in human hepatocellular carcinoma Hep3B cells.

Journal of Medicinal Chemistry published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Formula: C12H16O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia