Catalysis-chemistry

Zubkov, Mikhail O. published the artcilePhotocatalyzed Decarboxylative Thiolation of Carboxylic Acids Enabled by Fluorinated Disulfide, SDS of cas: 2051-95-8, the publication is Organic Letters (2022), 24(12), 2354-2358, database is CAplus and MEDLINE.

Thiolation of carboxylic acids using a disulfide reagent having tetrafluoropyridinyl groups was described. The light-mediated process was performed using an acridine-type photocatalyst. Primary, secondary, tertiary and heteroatom-substituted carboxylic acids could be thiolated, and the method could be applied to the late-stage modification of a range of naturally occurring compounds and drugs. The fluorinated pyridine fragment was believed to enable the C-S bond formation. The resulting sulfides were used as redox-active radical precursors.

Organic Letters published new progress about 2051-95-8. 2051-95-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ketone, name is 3-Benzoylpropionicacid, and the molecular formula is C6H8N2, SDS of cas: 2051-95-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zubkov, Mikhail O. published the artcilePhotocatalyzed Decarboxylative Thiolation of Carboxylic Acids Enabled by Fluorinated Disulfide, Application In Synthesis of 118-90-1, the publication is Organic Letters (2022), 24(12), 2354-2358, database is CAplus and MEDLINE.

Thiolation of carboxylic acids using a disulfide reagent having tetrafluoropyridinyl groups was described. The light-mediated process was performed using an acridine-type photocatalyst. Primary, secondary, tertiary and heteroatom-substituted carboxylic acids could be thiolated, and the method could be applied to the late-stage modification of a range of naturally occurring compounds and drugs. The fluorinated pyridine fragment was believed to enable the C-S bond formation. The resulting sulfides were used as redox-active radical precursors.

Organic Letters published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H6ClF3, Application In Synthesis of 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kuznetsov, A. I. published the artcileHeteroadamantanes and their derivatives. 4. Synthesis of 1,3,5-triazaadamantane, Recommanded Product: 1,3,5-Triazaadamantan-7-amine, the publication is Khimiya Geterotsiklicheskikh Soedinenii (1985), 837-40, database is CAplus.

7-Hydroxyamino- and 7-amino-1,3,5-triazaadamantane I [R = NHOH, NH₂ (II)] were obtained in 67 and 90.3%, resp., by reduction of the 7-nitro derivative by N₂H₄.H₂O in the presence of Raney Ni. Treating II with concentrated HBr and aqueous NaNO₂ gave 52.9% I (R = Br) which was debrominated by N₂H₄.H₂O in the presence of Raney Ni to give 95% title compound I (R = H). The latter was also obtained from I (R = SCN) in 60.3% yield by treatment with Raney Ni in Me₂CHOH.

Khimiya Geterotsiklicheskikh Soedinenii published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, Recommanded Product: 1,3,5-Triazaadamantan-7-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shao, Yu published the artcileSingle Solid Precursor-Derived Three-Dimensional Nanowire Networks of CuZn-Silicate for CO₂ Hydrogenation to Methanol, Safety of 3-(Trimethoxysilyl)propan-1-amine, the publication is ACS Catalysis (2022), 12(10), 5750-5765, database is CAplus.

Hydrogenation of CO₂ to MeOH is one of the most promising technologies in mitigating the emissions of CO₂ and tackling the challenge of climate change. In this work, we present a synthetic protocol for preparing a Cu-ZnO-based heterogeneous catalyst supported by siliceous nanowire networks from a single solid precursor with a tunable composition The resulting Si-Cu-Zn catalysts were evaluated with the MeOH synthesis from the CO₂ hydrogenation reaction operated at moderate conditions (30 barg and 200-280¡ãC). A specific MeOH yield of 402 mg_MeOH¡¤g_Cu^-1¡¤h^-1 and a MeOH selectivity of 51% were obtained at 240¡ãC. Such a performance was attributed to several structural and compositional merits, granted through the attentively engineered synthetic procedures. Small Cu nanoparticle (NP) size was achieved and maintained by the high dispersion of Cu to the at. level in the precatalyst and the incorporation of ZnO as a structural promoter. Moreover, the desirable Cu-ZnO synergistic effect can be further attained from the strong metal-support interaction (SMSI) between the Cu NPs and the partially reduced ZnO phase. Lastly, the robust siliceous nanowire networks provided decent spatial confinement to contain the growth of Cu NPs while offering high accessibility with the macroscopic porous morphol. The catalyst exhibited stable performance over a week’s long stability test while keeping its structural integrity intact. Overall, this study may offer an alternative design and synthesis strategy for the well-received Cu-ZnO system to approach its high performance in CO₂ hydrogenation.

ACS Catalysis published new progress about 13822-56-5. 13822-56-5 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is 3-(Trimethoxysilyl)propan-1-amine, and the molecular formula is C13H19Br2ClN2O, Safety of 3-(Trimethoxysilyl)propan-1-amine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hara, Toshihiko published the artcileDevelopment of ¹⁸F-fluoroethylcholine for cancer imaging with PET: synthesis, biochemistry, and prostate cancer imaging, Related Products of catalysis-chemistry, the publication is Journal of Nuclear Medicine (2002), 43(2), 187-199, database is CAplus and MEDLINE.

The effectiveness of ¹¹C-choline PET in detecting various cancers, including prostate cancer, is well established. This study was aimed at developing an ¹⁸F-substituted choline analog, ¹⁸F-fluoroethylcholine (FECh), as a tracer of cancer detection. Methods: No-carrier-added ¹⁸F-FECh was synthesized by 2-step reactions: First, tetrabutylammonium (TBA) ¹⁸F-fluoride was reacted with 1,2-bis(tosyloxy)ethane to yield 2-¹⁸F-fluoroethyl tosylate; and second, 2-¹⁸F-fluoroethyl tosylate was reacted with N,N-dimethylethanolamine to yield ¹⁸F-FECh, which was then purified by chromatog. An automated apparatus was constructed for preparation of the ¹⁸F-FECh injection solution In vitro experiments were performed to examine the uptake of ¹⁸F-FECh in Ehrlich ascites tumor cells, and the metabolites were analyzed by solvent extraction followed by various kinds of chromatog. Clin. studies of ¹⁸F-FECh PET were performed on patients with untreated primary prostate cancer as follows: A dynamic ¹⁸F-FECh PET study was performed on 1 patient and static PET studies were performed on 16 patients, and the data were compared with those of ¹¹C-choline PET on the same patients. Results: ¹⁸F-FECh was prepared in high yield and purity. The performance of the automated apparatus was excellent. The in vitro experiment revealed that ¹⁸F-FECh was incorporated into tumor cells by active transport, then phosphorylated (yielding phosphoryl-¹⁸F-FECh) in the cells, and finally integrated into phospholipids. The clin. PET studies showed marked uptake of ¹⁸F-FECh in prostate cancer. A dynamic PET study on 1 patient revealed that the blood level of ¹⁸F-FECh decreased rapidly (in 1 min), the prostate cancer level became almost maximal in a short period (1.5 min) and it remained constant for a long time (60 min), and the urinary radioactivity became prominent after a short time lag (5 min). Static PET studies conducted under bladder irrigation showed no difference between ¹⁸F-FECh uptake and ¹¹C-choline uptake in prostate cancer. However, ¹⁸F-FECh gave a slightly higher spatial resolution of the image, which was attributed to the shorter positron range of ¹⁸F. Conclusion: The synthesis of ¹⁸F-FECh was easy and reliable. ¹⁸F-FECh PET was very effective in detecting prostate cancer in patients. The chem. trap, consisting of active transport of ¹⁸F-FECh and formation of phosphoryl-¹⁸F-FECh, seemed to be involved in the uptake mechanism of ¹⁸F-FECh in tumors.

Journal of Nuclear Medicine published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ovseenko, L. V. published the artcileBulk properties of solutions of the acetates of primary aliphatic amines, Name: Dodecylamineacetate, the publication is Kolloidnyi Zhurnal (1992), 54(1), 121-4, database is CAplus.

The colloid-chem. properties of aqueous primary aliphatic amine acetates containing C₁₂-C₁₈ hydrocarbon radicals were studied by conductometric and viscosimetric methods. The critical concentrations of spherical micelle formation (CCM_I) and of the transition of micelles from the spherical to nonspherical form (CCM_II) were determined This is accompanied by a decrease in the molar volume of a hydrated micelle and by a change in the structural-rheol. properties of the system.

Kolloidnyi Zhurnal published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Name: Dodecylamineacetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ovseenko, L. V. published the artcileStructure formation in the solutions of aliphatic amines by solubilization of monohydric alcohols, Formula: C14H31NO2, the publication is Kolloidnyi Zhurnal (1993), 55(6), 70-3, database is CAplus.

The influence of aliphatic alcs. (n-hexanol, n-octanol) on micellar properties was studied for solutions of primary aliphatic amine acetates with alkyl chain lengths C₁₂-C₁₈. Small amounts of the alcs. decrease the CMC₁ of amine salt and increase the CMC₂, broadening the region of spherical micelle existence. This in turn influences the state of these collectors in concentrated electrolyte solutions, and their adsorption and flotation activities.

Kolloidnyi Zhurnal published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Formula: C14H31NO2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Volpina, Olga M. published the artcileProteolytic degradation patterns of the receptor for advanced glycation end products peptide fragments correlate with their neuroprotective activity in Alzheimer’s disease models, HPLC of Formula: 71989-31-6, the publication is Drug Development Research (2021), 82(8), 1217-1226, database is CAplus and MEDLINE.

The receptor for advanced glycation end products (RAGE) plays an essential role in Alzheimer’s disease (AD). We previously demonstrated that a fragment (60-76) of RAGE improved the memory of olfactory bulbectomized (OBX) and Tg 5 x FAD mice – animal models of AD. The peptide analog (60-76) with protected N- and C-terminal groups was more active than the free peptide in Tg 5 x FAD mice. This study investigated proteolytic cleavage of the RAGE fragment (60-76) and its C- and N-terminally modified analog by blood serum using HPLC and mass spectrometry. The modified peptide was proteolyzed slower than the free peptide. Degrading the protected analog resulted in shortened fragments with memory-enhancing effects, whereas the free peptide yielded inactive fragments. After administering the different peptides to OBX mice, their performance in a spatial memory task revealed that the ED of the modified peptide was five times lower than that of the free peptide. HPLC and mass spectrometry anal. of the proteolytic products allowed us to clarify the differences in the neuroprotective activity conferred by administering these two peptides to AD animal models. The current study suggests that the modified RAGE fragment is more promising for the development of anti-AD therapy than its free analog.

Drug Development Research published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H28B2O4S2, HPLC of Formula: 71989-31-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shermolovich, Yu. G. published the artcileReaction of N-alkyl- and N-(arylsulfonyl)sulfinimidic acid chlorides with triphenylphosphine, HPLC of Formula: 19117-31-8, the publication is Zhurnal Organicheskoi Khimii (1991), 27(10), 2245-6, database is CAplus.

Reaction of ArSCl:NBu-tert [Ar = (un)substituted Ph] with PPh₃ afforded aminyl radicals ArSN^?Bu-tert + Ph₃PCl₂. ArSCl:NSO₂Ar’ (Ar, Ar’ as above) underwent transimidation with PPh₃, affording Ph₃P:NSO₂Ar’.

Zhurnal Organicheskoi Khimii published new progress about 19117-31-8. 19117-31-8 belongs to catalysis-chemistry, auxiliary class Oxidant, name is N-(tert-Butyl)-S-phenylthiohydroxylamine, and the molecular formula is C9H7NO4, HPLC of Formula: 19117-31-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Huang, Dejian published the artcileFacile and Reversible Cleavage of C-F Bonds. Contrasting Thermodynamic Selectivity for Ru-CF₂H vs F-Os:CFH, Application of Trimethyl(perfluorophenyl)silane, the publication is Journal of the American Chemical Society (2000), 122(37), 8916-8931, database is CAplus.

In the presence of a catalytic amount of F^– (CsF), Me₃SiR_f (R_f = CF₃ and C₆F₅) exchanges R_f with fluoride of the 16-electron complexes MHF(CO)L₂ (M = Ru, Os; L = PⁱPr₃, P^tBu₂Me) to give Me₃Si-F and the unsaturated pentafluorophenyl complexes, MH(C₆F₅)(CO)L₂, or (when R_f = CF₃) saturated fluorocarbene complexes, MHF(CF₂)(CO)L₂, via ¦Á-F migration. X-ray crystal structure and solution ¹⁹F NMR studies reveal that, in the ground state, the three atoms of the CF₂ group lie in a plane perpendicular to the P-Ru-P axis so that the ¦Ð-back-donation is maximized and the carbene substituents are inequivalent. Having hydride trans to the CF₂ ligand, MHF(CF₂)(CO)L₂ is a kinetic product, which converts to a thermodn. isomer. For Ru, the final product is a 16e complex, RuF(CF₂H)(CO)L₂, formed by combination of CF₂ and hydride. For Os, the product is an 18e complex, OsF₂(:CFH)(CO)L₂, resulting from exchange of one carbene fluoride with the hydride. The distinct difference between Os and Ru demonstrates the principle that 3rd-row transition metals show a pronounced tendency toward a higher oxidation state. The isomerization mechanism involves phosphine dissociation as a slow step. Coordinatively saturated RuHF(CF₂)(CO)L₂ reacts with CO within the time of mixing to give the F and CF₂ recombination product, RuH(CF₃)(CO)₂L₂. This unexpectedly fast carbonylation reaction, as well as ¹⁹F spin saturation transfer experiments, reveals the existence of a fast ¦Á-F migration equilibrium between RuHF(CF₂)(CO)L₂ and RuH(CF₃)(CO)L₂ in solution In sharp contrast, the Os analog does not have such a fast equilibrium, and therefore it does not react with CO at room temperature At higher temperature, reaction occurs forming the hydride and fluoride exchanged product, Os(CHF₂)(F)(CO)₂L₂. The contrasting behavior of Ru vs. Os regarding stability of fluoroalkyl and fluorocarbene is discussed on the basis of the theor. calculations, which also provide insight into the isomerization of RuHF(CF₂)(CO)L₂. Hydrogenolysis of Ru(CF₂H)F(CO)L₂ liberates CH₂F₂, forming RuHF(CO)L₂.

Journal of the American Chemical Society published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Application of Trimethyl(perfluorophenyl)silane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia