Catalysis-chemistry

Liu, Jinghong published the artcileChar Structure and Charring Mechanism of Phosphazene-Based Epoxy Resin during Combustion, Synthetic Route of 191-07-1, the publication is Polymer Degradation and Stability (2022), 109927, database is CAplus.

The char structure and charring mechanism were important factors in determining the flame retardancy of the polymer. However, relevant research on phosphazene-based polymers, which have excellent fire retardancy, was limited. In our previous work, a phosphazene-based epoxy resin (EHEP-D230) was obtained with a honeycomb-like structure char after combustion. Herein, we further investigated gaseous phase degradation products of the resin through TGA-FTIR, while the condensed phase degradation products, the char, were studied using a variety of characterization techniques, including EDS mapping, FTIR, XPS, solid ³¹P-NMR and Raman. The study shows that nitrogen products of phosphazene were found in both the gaseous (e.g. NH₃) and condensed phases (e.g. pyridine, pyrrole, and quaternary-nitrogen structure), whereas phosphorus products (e.g. phosphoric acid-like structures) were discovered in the condensed phase with an uneven distribution. This finding was confirmed by the degradation of the other two phosphazene epoxy resins (HGETP-D230 and HGETP-MNA). Addnl., the distance between two defects in the EHEP-D230 char (doped carbon structures) might range between 5.6 ? and 17.2 ?, indicating that the char of EHEP-D230 is highly disordered. Subsequently, we compared our research results with those of previous studies on phosphazene degradation in the field of epoxy, and offered a global chem. structure of EHEP-D230’s char. Furthermore, a charring mechanism involving the aggregating-pressing process of phosphorous was proposed.

Polymer Degradation and Stability published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Synthetic Route of 191-07-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Liu, Xue-Li published the artcileAsymmetric Synthesis of Functionalized Nitrophenols via a Copper(II)-Mediated Bromination/Debromination Aromatization Sequence, Safety of 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, the publication is Asian Journal of Organic Chemistry (2017), 6(8), 967-972, database is CAplus.

2″A stereospecific copper(II)-mediated bromination/debromination aromatization sequence leading to functionalized nitrophenols I (R¹ = H, 4-Me, 4-Et, 3-Me; R² = 3-methoxypheyl, 2-naphthyl, thiophen-2-yl, etc.) from corresponding ¦Ã-nitroketones II is described. This provides a simple methodol. for the construction of nitrophenols I in moderate to good yields and moderate to high enantioselectivities.

Asian Journal of Organic Chemistry published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Safety of 1,2-Dimethoxy-4-(2-nitrovinyl)benzene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sena, Arlene C. published the artcileA systematic review of syphilis serological treatment outcomes in HIV-infected and HIV-uninfected persons: rethinking the significance of serological non-responsiveness and the serofast state after therapy, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine, the publication is BMC Infectious Diseases (2015), 479/1-479/15, database is CAplus and MEDLINE.

Syphilis remains a global public health threat and can lead to severe complications. In addition to resolution of clin. manifestations, a reduction in nontreponemal antibody titers after treatment is regarded as “proof of cure.” However, some patients manifest < 4-fold decline (“serol. non-response”) or persistently pos. nontreponemal titers despite an appropriate decline (“serofast”) that may represent treatment failure, reinfection, or a benign immune response. To delineate these treatment phenomena, we conducted a systematic review of the literature regarding serol. outcomes and associated factors among HIV-infected and -uninfected subjects. Six databases (PubMed, Embase, CINAHL, Web of Science, Scopus, and BIOSIS) were searched with no date restrictions. Relevant articles that evaluated serol. treatment responses and correlates of serol. cure (¡Ý fourfold decline in nontreponemal titers) were included. We identified 1693 reports in the literature, of which 20 studies met selection criteria. The median proportion of patients who had serol. non-response was 12.1 % overall (interquartile range, 4.9-25.6), but varied depending on the time points after therapy. The serofast proportion could only be estimated from 2 studies, which ranged from 35.2-44.4 %. Serol. cure was primarily associated with younger age, higher baseline nontreponemal titers, and earlier syphilis stage. The relationship between serol. cure and HIV status was inconsistent; among HIV-infected patients, CD4 count and HIV viral load was not associated with serol. cure. Serol. non-response and the serofast state are common syphilis treatment outcomes, highlighting the importance of determining the immunol. and clin. significance of persistent nontreponemal antibody titers after therapy.

BMC Infectious Diseases published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C9H7NO3, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

He, Chao published the artcileSynthesis of structurally diverse diarylketones through the diarylmethyl sp³ C-H oxidation, Application In Synthesis of 457-68-1, the publication is Tetrahedron Letters (2014), 55(32), 4458-4462, database is CAplus.

Under open-flask conditions, an efficient method to assemble a series of diversely functionalized diarylketones in the presence of com. available NBS has been developed. Yields of up to 99% have been achieved employing diarylmethanes as starting material. Based on ¹⁸O-labeled experiment, the addition of stoichiometric water eventually leads to excellent yields in all carbonylation cases.

Tetrahedron Letters published new progress about 457-68-1. 457-68-1 belongs to catalysis-chemistry, auxiliary class Fluoride,Benzene, name is Bis(4-fluorophenyl)methane, and the molecular formula is C13H10F2, Application In Synthesis of 457-68-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chen, Yaoxia published the artcileSupramolecular nanofibers with superior anti-angiogenesis and antitumor properties by enzyme-instructed self-assembly (EISA), Product Details of C20H19NO4, the publication is Chemical Engineering Journal (Amsterdam, Netherlands) (2021), 130531, database is CAplus.

Currently, combination therapy has become a popular research topic in cancer therapy. However, the outcome of the current combination therapy strategy does not satisfy the demand for clin. applications because of factors such as their overlapping toxicities, poor drug payload, and inevitable therapy resistance. Supramol. self-assembly of peptides holds great potential for solving relevant problems and achieving superior therapeutic effects. In this study, we aimed to propose supramol. self-assemblies based on a combination therapy strategy, consisting of a heptapeptide A7R for the inhibition of angiogenesis, the chemotherapeutic drug HCPT for treating numerous tumors with high efficacy, and an efficient self-assembling mol. FFY to improve drug loading and cell permeability. We regulated the secondary structure of nanomaterials by optimizing the pathways of self-assembly and significantly improved the affinity of A7R peptide to NRP-1. Endothelial tube formation in Matrigel and a tumor mouse model (in vivo) were then performed to demonstrate the superior antitumor effects of our supramol. self-assemblies both in vitro and in vivo. In summary, this work not only provides a promising platform for the development of effective combination therapy, but also offers a useful strategy to prepare self-assembled nanomaterials with optimized performance.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Product Details of C20H19NO4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yang, Huan published the artcileDithiosulfindene Adsorption and Reaction on Gold Nanoparticles in Water, Product Details of C14H10O4S2, the publication is Journal of Physical Chemistry C (2020), 124(1), 686-692, database is CAplus.

Dithiosulfindene (DTS) is a model mol. for dithiolethiones, a class of biomedically important sulfur-rich compounds with the general formula R₁-S-S-C( = S)-R₂. Reported herein is a combined exptl. and computational study of DTS interactions with plasmonic gold nanoparticles (AuNPs) in water. DTS adsorptions and reactions on AuNPs were investigated using a combination of UV-vis, Raman, and surface-enhanced Raman spectroscopy (SERS) methods. The saturation packing d. of DTS on AuNPs is 596 pmol/cm², and its structure and conformation on AuNP surfaces depend critically on its packing d. NaOH reacts with DTS both in water and on AuNPs, converting DTS into thiosalicylic acid (TSA). TSA produced by NaOH reaction with DTS preadsorbed onto AuNPs partitions between remaining on the AuNP surfaces and being released to the supernatant of the reaction solution UV-vis measurements revealed that NaOH reaction with DTS in solution and on AuNPs both follow first-order kinetics with a rate constant of 0.71 and 2.94 h^-1, resp. In contrast, SERS is highly effective in detecting the completeness of the reactions and informative for identifying the reaction products, but is unreliable for either in situ monitoring of the NaOH reaction with DTS adsorbed on aggregated AuNPs or ex situ detecting of solution composition change from NaOH reaction with DTS in solution The insights derived from this study should be important for developing an in-depth understanding of dithiolethione adsorptions and reactivities on AuNPs. This work also highlights the advantages and limitations of SERS for both in situ and ex situ monitoring of chem. reactions in solutions

Journal of Physical Chemistry C published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C18H24N6O6S4, Product Details of C14H10O4S2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zheng, Suhua published the artcileMagnesium-Promoted Reductive Carboxylation of Aryl Vinyl Ketones: Synthesis of ¦Ã-Keto Carboxylic Acids, COA of Formula: C10H10O3, the publication is Journal of Organic Chemistry (2022), 87(11), 7342-7349, database is CAplus and MEDLINE.

Direct reductive carboxylation of aryl vinyl ketones under the atm. of carbon dioxide led to the selective formation of ¦Ã-keto carboxylic acids ArC(O)CH₂CHR¹C(O)OH [Ar = Ph, 2-MeC₆H₄,4-FC₆H₄, etc.; R¹ = Me, Et, ph] in 38-86% yields. The reaction was characterized by the carbon-carbon bond formation of carbon dioxide at the ¦Â-position of enone, with the use of magnesium turnings that can be easily handled as the reducing agent and the eco-friendly reaction conditions such as no pressuring, no lower or higher reaction temperature, and short reaction time. This protocol showed a wide substrate scope and provided a useful and convenient alternative to access biol. important ¦Ã-keto carboxylic acids which then converted to esters of ¦Ã-keto carboxylic acids under the typical esterification conditions.

Journal of Organic Chemistry published new progress about 2051-95-8. 2051-95-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ketone, name is 3-Benzoylpropionicacid, and the molecular formula is C9H4F6O, COA of Formula: C10H10O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ruan, Xiao-Yun published the artcilePhotoinduced and palladium-catalyzed hydrogen atom transfer triggered 1,2-difunctionalization of 1,3-dienes with hydroxamides, Computed Properties of 118-90-1, the publication is Science China: Chemistry (2022), 65(5), 863-869, database is CAplus.

The discovery of novel catalysis modes to generate a significant increase in structural complexity from readily available reactants is a fundamental goal in modern organic synthesis. Here, Authors report a photoinduced palladium-catalyzed hydrogen atom transfer triggered 1,2-difunctionalization of conjugated dienes. Without the employment of exogeneous photosensitizers and external oxidants, the cascade reaction realized the integration of remote functionalization of various C(sp³)-H bonds and selective difunctionalization of 1,3-dienes with 100% atom efficiency, allowing for the synthesis of structurally diverse amides with up to 90% yields. Given the prevalence of amides in pharmaceuticals and natural products, the current protocol has provided an efficient means to access highly functionalized amides from readily available carboxylic acid derivatives and 1,3-dienes.

Science China: Chemistry published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, Computed Properties of 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tan, Bochuan published the artcileExperimental and theoretical studies on the inhibition properties of three diphenyl disulfide derivatives on copper corrosion in acid medium, Category: catalysis-chemistry, the publication is Journal of Molecular Liquids (2020), 111975, database is CAplus.

2,2′-Dithiosalicylic acid (DSA), 2-aminophenyl disulfide (APD) and 2,2-dibenzamidodiphenyl disulfide (DPD) were determined for corrosion inhibition of Cu in H₂SO₄ media by electrochem. tests, surface morphol. anal., quantum chem. calculations and mol. dynamics simulations. The results of polarization curves showed that DSA, APD and DPD reveal good anti-corrosion capacity. They can simultaneously inhibit the cathodic and anodic reactions of copper. Therefore, they belong to the mixed-type corrosion inhibitors. Impedance spectroscopy results showed that when DSA, APD and DPD adsorption on the surface of Cu, the charge transfer resistance increases significantly and typical capacitance behavior produced, which indicates that the formed inhibitor film is very dense and ordered. In addition, the adsorption of corrosion inhibitors on the Cu surface is conforming to Langmuir monolayer adsorption. The exptl. results obtained by surface topog. anal. are consistent with the results of electrochem. experiments Their corrosion inhibition ability is DSA < APD < DPD. Theor. calculations further explore the relationship between corrosion inhibition performance and their mol. configurations.

Journal of Molecular Liquids published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C15H24S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ding, Lei published the artcileSynthesis and biological evaluation of novel 5,6-dihydrobenzo[h]quinazoline derivatives as FLT3 inhibitors, Quality Control of 104-03-0, the publication is Chemical Biology & Drug Design (2022), 99(4), 527-534, database is CAplus and MEDLINE.

Fms-like tyrosine kinase 3 (FLT3) is widely expressed and often mutated in acute myeloid leukemia (AML), which makes it an important target for the treatment of AML. The structure-based synthesis and biol. evaluation of 5,6-dihydrobenzo[h]quinazoline derivatives as FLT3 inhibitors have been studied in this paper. Compound I derivatives (X and Y = N, CH, CF, or CCH₃ and R = isoxazole derivatives) displayed comparable inhibitory potency against FLT3-ITD and showed remarkable antiproliferative activities against MV4-11.

Chemical Biology & Drug Design published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C8H7NO4, Quality Control of 104-03-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia