Catalysis-chemistry

Zeng, Xiang published the artcileAlterations of the gut microbiota and metabolomics in children with e-waste lead exposure, Safety of 2-Methylbenzoic acid, the publication is Journal of Hazardous Materials (2022), 128842, database is CAplus and MEDLINE.

A lead (Pb) exposure can alter the composition and metabolites of gut microbiota. However, few studies investigated this association in the children. A total of 551 children aged 3-7 years were recruited from Guiyu (the e-waste dismantling area) and Haojiang (the reference area). There were finally 70 subjects met the inclusive criteria. Blood and urinary Pb concentrations were detected by GFAAS and ICP-MS techniques. The microbiota and metabolites were measured in stool samples using 16 S rRNA MiSeq sequencing technol. and gas chromatog.-mass spectrometry (GC-MS), resp. Average Pb concentrations in the blood and urine of children were higher in Guiyu than in Haojiang. There were 58 kinds of differential genera and 19 types of discrepant metabolites between the two groups, and wide and significant correlations were found between them. Exposure to Pb caused the most significant differences in microbiota, metabolites, and phys. development parameters between the two groups in terms of microbiota, metabolites, and phys. development indicators. Sphingolipid metabolism and ion transport may also be altered by Pb exposure. Exposure to Pb is associated with significant alterations in the gut microbiota and metabolome in children. More research is needed to confirm the findings of this study.

Journal of Hazardous Materials published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C5H5NO3S, Safety of 2-Methylbenzoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chen, Yu-Ping published the artcileParticle size-resolved emission characteristics of complex polycyclic aromatic hydrocarbon (PAH) mixtures from various combustion sources, Safety of Coronene, the publication is Environmental Research (2022), 214(S), 113840, database is CAplus and MEDLINE.

Combustion of domestic solid fuels is a significant source of polycyclic aromatic hydrocarbons (PAHs). Some oxygenated PAHs (o-PAHs) and PAHs with mol. weight of 302 (MW302 PAHs) are more toxic than the traditional 16 priority PAHs, whereas their emissions were much less elucidated. This study characterized the size-dependent emissions of parent PAHs (p-PAHs), o-PAHs, and MW302 PAHs from various combustion sources. The estimated emission factors (eEFs) from biomass burning sources were highest for most of the PAHs (391-8928¦Ìg/kg), much higher than that of anthracite coal combustion (43.0-145¦Ìg/kg), both which were operated in an indoor stove. Cigarette smoking had a high eEF of o-PAHs (240 ng/g). MW302 PAHs were not found in the emissions of smoking, cooking, and vehicular exhausts. Particle-size distributions of PAHs were compound- and source-dependent, and the tendency to associate with smaller particles was observed especially in biomass burning and cigarette smoking sources. Furthermore, the inter-source differences in PAH eEFs were associated with their dominance in fine particles. PAH composition profiles also varied with the particle size, showing increasing contributions of large-mol. PAHs with decreasing sizes in most cases. The size distributions of p-PAHs are much more significantly dependent on their n-octanol/air partition coefficients and vapor pressures than those of o-PAHs, suggesting differences in mechanisms governing their distributions. Several mol. diagnostic ratios (MDRs), including two based on MW302 PAHs, specific to these combustion scenarios were identified. However, the MDRs within some sources are also strongly size-dependent, providing a new explanation for the uncertainty in their application for source identification of PAHs. This work also highlights the necessity for understanding the size-resolved atm. behaviors and fate of PAHs after their emission.

Environmental Research published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Safety of Coronene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bai, Xiang-Ru published the artcileEnvironmentally Safe Mercury(II) Ions Aided Zero-Background and Ultrasensitive SERS Detection of Dipicolinic Acid, COA of Formula: C18H15N3O3, the publication is Analytical Chemistry (Washington, DC, United States) (2017), 89(19), 10335-10342, database is CAplus and MEDLINE.

Field, reliable, and ultrasensitive detection of dipicolinic acid (DPA), a general biomarker of bacterial spores and especially Bacillus anthracis, is highly desirable but still challenging in the current biometric security emergency response system. Herein the authors report an environmentally safe mercury(II) ions-mediated and competitive coordination interaction based approach for rationally designed surface-enhanced Raman scattering (SERS)-active gold nanoparticles (AuNPs), enabling rapid, ultrasensitive and zero-background detection of DPA without the pretreatment of samples. By competitiveness, these papain-capped gold nanoparticles (P-AuNPs) are induced to undergo controllable aggregation upon the addition of Hg²⁺ ions and DPA with a concentration range (1 nM?8 ¦ÌM), which correspondingly cause quant. changes of SERS intensity of cresyl violet acetate (CVa) conjugated AuNPs. The decreased Raman intensity obtained by subtracting two cases of additives that contain only Hg²⁺ and the mixture of Hg²⁺ and DPA is proportional to the concentration of DPA over a range of 1 nM?8 ¦ÌM (R² = 0.9824), with by far the lowest limit of detection (LOD) of 67.25 pM (0.01 ppb, S/N = 3:1). Of particular significance, mercury(II) ions actually play two roles in the process of measurements: a mediator for two designed competitive ligands (DPA and papain) and also a scavenger for the possibly blended ligands due to the different interaction time between DPA and the interferent with Hg²⁺ ions, which guarantees the interference-free detection of DPA even under real conditions.

Analytical Chemistry (Washington, DC, United States) published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C18H15N3O3, COA of Formula: C18H15N3O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Cong, Yikang published the artcileNano Cu-CuFe₂O₄-catalyzed selective reduction of ¦Á,¦Â,¦Ã,¦Ä-unsaturated carbonyls in alcohol medium, Recommanded Product: 3-Benzoylpropionicacid, the publication is Youji Huaxue (2020), 40(8), 2411-2418, database is CAplus.

An efficient Cu-CuFe₂O₄ nanoparticle-catalyzed protodeboronation strategy has been developed for the chemoselective 1,4-reduction of ¦Á,¦Â,¦Ã,¦Ä-unsaturated ketones, carboxylic ester and cyano-ester e.g., I. This protocol has the advantageous of the use of alc. as hydrogen source and solvent, low catalyst loading (0.5 mol%), and excellent catalyst recyclability. Addnl., the Cu-CuFe₂O₄ catalyst has shown excellent performance in gram-scale reactions. Furthermore, the catalytic mechanism has also been discussed. The reactivity of (E)-¦Ã,¦Ä-unsaturated carbonyl products , an important class of ¦Ã,¦Ä-unsaturated alkenes e.g., II, enables easy access to (E)-1,5-diphenylpent-4-en-1-ol, 3-buten-1-amines III, 4-oxo-4-phenylbutanoic acid, cyclic ethers such as 2-benzyl-5-phenyloxolane, 2,6-diphenyloxane, and cyclic nitrones IV.

Youji Huaxue published new progress about 2051-95-8. 2051-95-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ketone, name is 3-Benzoylpropionicacid, and the molecular formula is C10H10O3, Recommanded Product: 3-Benzoylpropionicacid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kang, Ziyao published the artcileTransferrin receptor targeting segment T7 containing peptide gene delivery vectors for efficient transfection of brain tumor cells, Safety of Fmoc-Pro-OH, the publication is Drug Delivery (2022), 29(1), 2375-2385, database is CAplus and MEDLINE.

Successful gene therapy for brain tumors are often limited by two important factors, the existence of blood brain barrier (BBB) and inefficient transfection of brain tumor cells. In this study, we designed a series of peptide-based gene delivery vectors decorated with T7 segment for binding the transferrin (Tf) receptors which were highly expressed on brain tumor cells, and evaluated their ability of gene delivery. The physicochem. properties of peptide vectors or peptide/DNA complexes were studied as well. The in vitro transfection efficiency was investigated in normal and glioma cell lines. Among these complexes, PT-02/DNA complexes showed the highest transfection efficiency in glioma cells and low cytotoxicity in normal cell lines, and it could transport DNA across the BBB model in vitro. Furthermore, PT-02/DNA could deliver pIRES2-EGFP into the brain site of zebrafish in vivo. The designed peptide vectors offered a promising way for glioma gene therapy.

Drug Delivery published new progress about 71989-31-6. 71989-31-6 belongs to catalysis-chemistry, auxiliary class Amino acide derivatives,pyrrolidine, name is Fmoc-Pro-OH, and the molecular formula is C20H19NO4, Safety of Fmoc-Pro-OH.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yan, Gang published the artcileDivergent 2-Chloroquinazolin-4(3H)-one Rearrangement: Twisted-Cyclic Guanidine Formation or Ring-Fused N-Acylguanidines via a Domino Process, Synthetic Route of 140-28-3, the publication is Chemistry – A European Journal (2020), 26(11), 2486-2492, database is CAplus and MEDLINE.

A highly efficient 2-chloroquinazolin-4(3H)-one rearrangement was developed that predictably generated either twisted-cyclic or ring-fused guanidines in a single operation, depending on the presence of a primary vs. secondary amine in the accompanying diamine reagent. Exclusive formation of twisted-cyclic guanidines results from pairing 2-chloroquinazolinones with secondary diamines. Use of primary amine-containing diamines permited a domino quinazolinone rearrangement/intramol. cyclization gated through (E)-twisted-cyclic guanidines to afford ring-fused N-acylguanidines. This scalable, structurally tolerant transformation generated 55 guanidines and delivered twisted-cyclic guanidines with robust plasma stability and an abbreviated total synthesis of an antitumor ring-fused guanidine (4 steps, 55% yield).

Chemistry – A European Journal published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C11H22N2O4, Synthetic Route of 140-28-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Libalova, Helena published the artcileTranscription profiles in BEAS-2B cells exposed to organic extracts from particulate emissions produced by a port-fuel injection vehicle, fueled with conventional fossil gasoline and gasoline-ethanol blend, Product Details of C24H12, the publication is Mutation Research, Genetic Toxicology and Environmental Mutagenesis (2021), 503414, database is CAplus and MEDLINE.

Emissions from road traffic are among the major contributors to air pollution worldwide and represent a serious environmental health risk. Although traffic-related pollution has been most commonly associated with diesel engines, increasing evidence suggests that gasoline engines also produce a considerable amount of potentially hazardous particulate matter (PM). The primary objective of this study was to compare the intrinsic toxic properties of the organic components of PM, generated by a conventional gasoline engine fueled with neat gasoline (E0), or gasoline-ethanol blend (15% ethanol, volume/volume, E15). Our results showed that while E15 has produced, compared to gasoline and per kg of fuel, comparable particle mass (¦Ìg PM/kg fuel) and slightly more particles by number, the organic extract from the particulate matter produced by E15 contained a larger amount of harmful polycyclic aromatic hydrocarbons (PAHs), as determined by the chem. anal. To examine the toxicity, we monitored genome-wide gene expression changes in human lung BEAS-2B cells, exposed for 4 h and 24 h to a subtoxic dose of each PM extract After 4 h exposure, numerous dysregulated genes and processes such as oxidative stress, lipid and steroid metabolism, PPAR¦Á signaling and immune response, were found to be common for both extract treatments. On the other hand, 24 h exposure resulted in more distinctive gene expression patterns. Although we identified several common modulated processes indicating the metabolism of PAHs and activation of aryl hydrocarbon receptor (AhR), E15 specifically dysregulated a variety of other genes and pathways related to cancer promotion and progression. Overall, our findings suggest that the ethanol addition to gasoline changed the intrinsic properties of PM emissions and increased the PAH content in PM organic extract, thus contributing to a more extensive toxic response particularly after 24 h exposure in BEAS-2B cells.

Mutation Research, Genetic Toxicology and Environmental Mutagenesis published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C24H12, Product Details of C24H12.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Xue, Weijian published the artcilePillar[n]MaxQ: A New High Affinity Host Family for Sequestration in Water, Formula: C3H12Cl2N2, the publication is Angewandte Chemie, International Edition (2020), 59(32), 13313-13319, database is CAplus and MEDLINE.

The authors report the synthesis, x-ray crystal structure, and mol. recognition properties of pillar[n]arene derivative P[6]AS, which the authors refer to as Pillar[6]MaxQ along with analogs P[5]AS and P[7]AS toward guests 1-18. The ultratight binding affinity of P[5]AS and P[6]AS toward quaternary (di)ammonium ions renders them prime candidates for in vitro and in vivo noncovalent bioconjugation, for imaging and delivery applications, and as in vivo sequestration agents.

Angewandte Chemie, International Edition published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C12H9N3O4, Formula: C3H12Cl2N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zaitsev, Sergei Yu. published the artcileUltrathin chemosensory films with a photosensitive bis(crown ether) derivative, COA of Formula: C3H12Cl2N2, the publication is Mendeleev Communications (2008), 18(5), 270-272, database is CAplus.

The spectral and isotherm changes observed for a new photosensitive bis(crown ether) derivative assigned as optical mol. tweezers (OMT) in mixed monolayers with stearic acid by addition of ammonium and diammonium salts indicated the strongest complex formation between OMT and 1,3-diaminopropane dihydrochloride that may be of particular interest for design of chemosensory nanomaterials.

Mendeleev Communications published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C4Br2N2O4S, COA of Formula: C3H12Cl2N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zaitsev, S. Yu. published the artcileThin films with immobilized bis-crown-ether dye, Synthetic Route of 10517-44-9, the publication is Colloids and Surfaces, A: Physicochemical and Engineering Aspects (2011), 383(1-3), 120-124, database is CAplus.

Thin films based on photosensitive bis-crown-ether dye were prepared by Langmuir and “modified spreading” techniques. The maximal changes in the surface pressure – and surface potential-mol. area isotherms (the relative mol. area increase was about 16%), in the absorption (shifts of ¦Ë _max up to 9 nm) and fluorescence (shifts of ¦Ë _max up to 17 nm) spectra of these films in the presence of diaminoalkane dihydrochlorides in the aqueous subphase were found.

Colloids and Surfaces, A: Physicochemical and Engineering Aspects published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C12H15ClO3, Synthetic Route of 10517-44-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia