Catalysis-chemistry

Zhuang, Zhe published the artcileLigand-Enabled ¦Â-C(sp³)-H Olefination of Free Carboxylic Acids, Application of 2-Methyl-4-phenylbutanoic acid, the publication is Journal of the American Chemical Society (2018), 140(32), 10363-10367, database is CAplus and MEDLINE.

An acetyl-protected aminoethyl Ph thioether has been developed to promote C(sp³)-H activation. Significant ligand enhancement is demonstrated by the realization of the first Pd(II)-catalyzed olefination of C(sp³)-H bonds of free carboxylic acids without using an auxiliary. Subsequent lactonization of the olefinated product via 1,4 addition provided exclusively monoselectivity in the presence of multiple ¦Â-C-H bonds. The product ¦Ã-lactone can be readily opened to give either the highly valuable ¦Â-olefinated or ¦Ã-hydroxylated aliphatic acids. Considering the challenges in developing Heck couplings using alkyl halides, this reaction offers a useful alternative.

Journal of the American Chemical Society published new progress about 1949-41-3. 1949-41-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene, name is 2-Methyl-4-phenylbutanoic acid, and the molecular formula is C7H8BFO2, Application of 2-Methyl-4-phenylbutanoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bibawy, Talaat A. published the artcileFlotation behavior of hematite, Name: Dodecylamineacetate, the publication is Tenside Detergents (1982), 19(1), 18-22, database is CAplus.

The flotation of hematite??[1317-60-8] was studied with cetyltrimethylammonium?bromide (I) [57-09-0], cetylpyridinium?bromide (II) [140-72-7], dodecylammonium?acetate (III) [2016-56-0], and cetylammonium?acetate (IV) [2016-52-6] as cationic collectors and Aerosol?OT (branched dodecylbenzenesulfonate) [577-11-7], Na?dodecyl?sulfate??[151-21-3], Na?dodecylbenzenesulfonate??[25155-30-0], and Na?oleate (V) [143-19-1] as anionic collectors. The flotation of hematite by I and II was <50%, indicating they are not efficient collectors. Flotation by III and IV was >75%. For anionic collectors, adsorption isotherms were similar except for V. Recoveries of hematite were maximum at the critical concentration of the collector.

Tenside Detergents published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Name: Dodecylamineacetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Saidalimu, Ibrayim published the artcileThe CF₃-DAST-induced deacylative trifluoromethylthiolation of cyclic 1,3-diketones/lactams/lactones and its extension to deacylative pentafluorophenylthiolation, COA of Formula: C9H9F5Si, the publication is Chemical Communications (Cambridge, United Kingdom) (2018), 54(63), 8761-8764, database is CAplus and MEDLINE.

A trifluoromethyl analog of diethylaminosulfur trifluoride (CF₃-DAST)-induced deacylative trifluoromethylthiolation of cyclic 1,3-diketones, lactams, and lactones that provide cyclic ¦Á-trifluoromethylthioketones, lactams, and lactones is reported. To the best of knowledge, this method represents the first example of the trifluoromethylthiolation of lactams. A corresponding deacylative pentafluorophenylthiolation using a pentafluorophenyl analog of diethylaminosulfur trifluoride (C₆F₅-DAST) was also attempted.

Chemical Communications (Cambridge, United Kingdom) published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, COA of Formula: C9H9F5Si.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yoshiji, Hitoshi published the artcileCombination of copper-chelating agent, trientine, and methotrexate attenuates colorectal carcinoma developmental and angiogenesis in mice, Recommanded Product: N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, the publication is Oncology Reports (2005), 14(1), 213-218, database is CAplus.

Recent studies have suggested that an antiangiogenic agent could improve the inhibitory effects of standard chemotherapeutic drugs against tumor development. We previously reported that the clin. used copper-chelating agent, trientine dihydrochloride (trientine), exerted strong anti-angiogenic activity and inhibited tumor growth. The aim of the current study was to examine the combined effect of trientine and methotrexate on the development and angiogenesis of xenograft human colorectal carcinoma (CRC) cells at clin. comparable low doses. When used individually, both trientine and methotrexate significantly suppressed CRC development along with inhibition of neovascularization in the tumor. A combination regimen of trientine and methotrexate exerted the most potent tumoricidal effect and led to ‘tumor dormancy.’. The combination of these agents also resulted in a marked suppression of the angiogenic factors, in particular the vascular endothelial growth factor and interleukin-8, and an increase of apoptosis in the tumor. In vitro studies revealed that neither trientine nor methotrexate was cytotoxic for tumor cells. On the other hand, the endothelial cell proliferation and tubular formation were significantly suppressed by these agents. The combined treatment of trientine and methotrexate at clin. comparable low doses could inhibit CRC development and angiogenesis, as well as suppress the angiogenic factors. Because both agents are widely used in clin. practice, the combination regimen may represent a potential new strategy for CRC therapy in the future.

Oncology Reports published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C3H5BN2O2, Recommanded Product: N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yuasa, M. published the artcileComputer-controlled synthesis of [¹⁸F]FDG by the tetrabutylammonium method: achievement of high yield, purity, reproducibility, reliability, and safety, HPLC of Formula: 17351-62-1, the publication is Applied Radiation and Isotopes (1997), 48(2), 201-205, database is CAplus.

The authors constructed a computer-controlled apparatus of no-carrier-added [¹⁸F]fluorodeoxyglucose ([¹⁸F]FDG) synthesis for routine clin. use. High yield, high reproducibility, and high quality of the product were achieved. The main step of the reaction is nucleophilic fluorination of the synthetic precursor, acetylated mannose triflate, with an activator, tetrabutylammonium bicarbonate. A biol. high quality medicinal environment (sterile and pyrogen-free) was achieved by employment of an inherently pyrodestructive chem. step within the process line and the use of pyrogen-free medical goods and heat-sterilized glassware. [¹⁸F]FDG was obtained in 70 min after EOB with a radiochem. yield of 57.7 ¡À 5.7% (decay corrected) and with radiochem. purity of > 99%.

Applied Radiation and Isotopes published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C4H6O3, HPLC of Formula: 17351-62-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tharamak, Sorachat published the artcileSynthesis of thymyl esters and their insecticidal activity against Spodoptera litura (Lepidoptera: Noctuidae), Related Products of catalysis-chemistry, the publication is Pest Management Science (2020), 76(3), 928-935, database is CAplus and MEDLINE.

Thymol, a natural phenolic monoterpene originating from Thymus vulgaris, is recognized as a safe and potent botanical insecticide to many insects. The structural modification of thymol into thymyl esters is a potential approach for the development of novel insecticides, which showed more toxicity than thymol. However, there are no reports on the insecticidal activity of thymyl esters to control Spodoptera litura. Thymol was structurally modified into ten thymyl esters by esterification using a new reagent, PPh₃/Br₃CSO₂Ph. The insecticidal activity of these compounds was examined against the second instars of Spodoptera litura using a topical application. Among the ten thymyl esters evaluated, thymyl cinnamate was the most toxic with LD₅₀ = 0.41 and 0.34 ¦Ìg/larva after 24 and 48 h posttreatment, resp. In addition, thymyl cinnamate-treated larvae showed increasing carboxylesterase and acetylcholinesterase activities in vivo experiment, whereas glutathione S-transferase activity showed no significant difference. Thymyl cinnamate were first reported to exhibit toxicity against S. litura 2.41-2.46 fold more efficient than thymol. However, the detailed biochem. interactions are necessary for further development of novel insecticides.

Pest Management Science published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C9H8N2O3, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Ohta, Shun published the artcileOxido-Bridged Di-, Tri-, and Tetra-Nuclear Iron Complexes Bearing Bis(trimethylsilyl)amide and Thiolate Ligands, Computed Properties of 22693-41-0, the publication is Inorganic Chemistry (2012), 51(4), 2645-2651, database is CAplus and MEDLINE.

Di-, tri-, and tetra-nuclear iron-oxido clusters with bis(trimethylsilyl)amide and thiolate ligands were synthesized from the reactions of Fe{N(SiMe₃)₂}₂ (1) with one equiv of thiol HSR (R = C₆H₅ (Ph), 4-^tBuC₆H₄, 2,6-Ph₂C₆H₃ (Dpp), 2,4,6-ⁱPr₃C₆H₂ (Tip)) and subsequent treatment with O₂. The trinuclear clusters [{(Me₃Si)₂N}Fe]₃(¦Ì₃-O){¦Ì-S(4-RC₆H₄)}₃ (R = H (3a), ^tBu (3b)) were obtained from the reactions of 1 with HSPh or HS(4-^tBuC₆H₄) and O₂, while the authors isolated a tetranuclear cluster [{(Me₃Si)₂N}₂Fe₂(¦Ì-SDpp)]₂(¦Ì₃-O)₂ (4) as crystals from an analogous reaction with HSDpp. Treatment of a tertrahydrofuran (THF) solution of 1 with HSTip and O₂ gave dinuclear [{(Me₃Si)₂N}(TipS)(THF)Fe]₂(¦Ì-O) (5). The mol. structures of these complexes were determined by x-ray crystallog. anal. Cyclic voltammograms of the mixed valent Fe(II)Fe(III)₂ complexes 3a and 3b are also presented which show a single one-electron oxidation and a single one-electron reduction for each of the two complexes.

Inorganic Chemistry published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Computed Properties of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Takata, Yoshiyuki published the artcileThe modified synthetic reaction of 2-alkylbenzimidazoles. Condensation of o-phenylenediamine with fatty acids in p-toluenesulfonic acid, Safety of 2-Butylhexanoic acid, the publication is Hokkaido Daigaku Kogakubu Kenkyu Hokoku (1980), 45-9, database is CAplus.

In the preparation of benzimidazoles (89-99% yield) by condensing RCO₂H (R = C_5-17?n-alkyl) with m-H₂NC₆H₄NH₂ 1 h at 170-200¡ã, the presence of p-MeC₆H₄SO₃H increased the yields. Even less reactive acids, such as Me₃CCO₂H and Bu₂CHCO₂H, gave the corresponding imidazoles in 26-84% yield.

Hokkaido Daigaku Kogakubu Kenkyu Hokoku published new progress about 3115-28-4. 3115-28-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is 2-Butylhexanoic acid, and the molecular formula is C9H11BO4, Safety of 2-Butylhexanoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Gao, Qing-qing published the artcilePreparation and properties of ammonium-based ionic liquids and polyether demulsifier complexes, Synthetic Route of 2016-56-0, the publication is Jingxi Huagong (2013), 30(1), 99-103, 107, database is CAplus.

Two kinds of ammonium-based ionic liquids, i. e. n-butylamine nitrate and dodecylamine acetate were synthesized. The effects of ammonium-based ionic liquid and crosslinking polyether demulsifier NJ-20 complexes on the dehydration of simulated crude oil emulsion were studied. The results showed that, when the dosage of the demulsifier complexes was 200 mg/L and the temperature was 50 degree, the dehydration rate reached 75% and 91%, resp., in 2 h. With sep. polyether demulsifier NJ-20, the dehydration rate was only 65% under the same conditions. When the dosage was 200 mg/L and the temperature was 40degree, the dehydration rate reached 59% in 2 h, which was much higher than that of polyether demulsifier NJ-20, displaying strong low-temperature demulsification effect.

Jingxi Huagong published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Synthetic Route of 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chang, Sheng published the artcileDesign and synthesis of novel 2-phenylaminopyrimidine (PAP) derivatives and their antiproliferative effects in human chronic myeloid leukemia cells, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, the publication is Molecules (2009), 14(10), 4166-4179, database is CAplus and MEDLINE.

A series of novel 2-phenylaminopyrimidine (PAP) derivatives structurally related to STI-571 were designed and synthesized. The abilities of these compounds to inhibit proliferation were tested in human chronic myeloid leukemia K562 cells. (E)-3-(2-bromophenyl)-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)phenyl]acrylamide(12d) was the most effective cell growth inhibitor and was 3-fold more potent than STI-571.

Molecules published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia