Catalysis-chemistry

Das, Sukant K. published the artcileTowards a stereoselective synthesis of α,α-disubstituted proline analogs, Synthetic Route of 4230-93-7, the publication is Tetrahedron Letters (2015), 56(37), 5172-5174, database is CAplus.

A mild organocatalytic protocol for the syntheses of α,α-disubstituted proline analogs has been developed. The 3-ketoproline scaffold was functionalized using various aromatic nitrostyrenes in the presence of a bifunctional organocatalyst. The resulting quaternary proline derivatives could easily be transformed into α-alkyl-β-hydroxyproline analogs. Furthermore, the methodol. could also be applied to the synthesis of 3-ketoproline functionalized peptides with high selectivity and good yields.

Tetrahedron Letters published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Synthetic Route of 4230-93-7.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Sharma, Sunny Kumar published the artcileOn mixed metric dimension of polycyclic aromatic hydrocarbon networks, Category: catalysis-chemistry, the publication is Chemical Papers (2022), 76(7), 4115-4128, database is CAplus.

Polycyclic aromatic hydrocarbons (PAHs) are a class of persistent organic contaminants that contain two or more aromatic rings. PAHs are commonly found in soil, water, and air, and result in mainly incomplete combustion of carbonaceous products. PAHs have a wide range of applications, such as interstellar species, optical and elec. materials, pharmaceutical industry, and other functional materials in petrochem. The chem. graph theory helps in understanding the complex structure of mols. The parameters of resolvability for graph Γ = (V,E) are a relatively novel advanced area where the entire structure is constructed so that each vertex (atom) or/and edge (bond) represents a unique position. In this paper, we study the resolvability parameter, i.e., mixed metric dimension for the complex mol. structure of PAHs. We also prove that the mixed metric dimension is unbounded and is not constant for PAHs.

Chemical Papers published new progress about 191-07-1. 191-07-1 belongs to catalysis-chemistry, auxiliary class Electronic Materials, name is Coronene, and the molecular formula is C18H34N4O5S, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Varaprasad, Bodala published the artcileCopper-catalyzed efficient access to 2,4,6-triphenyl pyridines via oxidative decarboxylative coupling of aryl acetic acids with oxime acetates, Quality Control of 104-03-0, the publication is New Journal of Chemistry (2021), 45(34), 15205-15209, database is CAplus.

An efficient and concise approach for the synthesis of 2,4,6-tri-Ph pyridines has been developed through copper-catalyzed oxidative decarboxylative coupling of C(sp³) aryl acetic acids with oxime acetates in DMF at 150° under an oxygen atm. Various functional groups were well tolerated and provided the corresponding 2,4,6-tri-Ph pyridines in good to excellent yields.

New Journal of Chemistry published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C23H28N2O4, Quality Control of 104-03-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nuri, Ayat published the artcilePd Nanoparticles Stabilized on the Cross-Linked Melamine-Based SBA-15 as a Catalyst for the Mizoroki-Heck Reaction, Quality Control of 13822-56-5, the publication is Catalysis Letters (2022), 152(4), 991-1002, database is CAplus.

Mesoporous SBA-15 silicate with a high surface area was prepared by a hydrothermal method, successively modified by organic melamine ligands and then used for deposition of Pd nanoparticles onto it. The synthesized materials were characterized with IR spectroscopy (FT-IR), thermogravimetric anal. (TGA), nitrogen physisorption, SEM (SEM) coupled with energy dispersive X-ray anal. (EDX), transmission electron microscopy (TEM), NMR (NMR) and inductively coupled plasma (ICP-OES). The catalyst was effectively used in the Mizoroki-Heck coupling reaction of various reactants in the presence of an organic base giving the desired products in a short reaction time and with small catalysts loadings. The reaction parameters such as the base type, amounts of catalyst, solvents, and the temperature were optimized. The catalyst was easily recovered and reused at least seven times without significant activity losses.

Catalysis Letters published new progress about 13822-56-5. 13822-56-5 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is 3-(Trimethoxysilyl)propan-1-amine, and the molecular formula is C6H17NO3Si, Quality Control of 13822-56-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Uzunoglu, Serap Beyaztas published the artcileInhibition effect of some chemical on lactoperoxidase and covalently immobilized on a biocomposite for biosensor, Related Products of catalysis-chemistry, the publication is Fresenius Environmental Bulletin (2020), 29(11), 9924-9933, database is CAplus.

Lactoperoxidase was purified from bovine milk using ammonium sulfate precipitation and affinity chromatog. The greatest purification fold for lactoperoxidase has been obtained as 1302.65 folds with 24.95% yields. The purity of the enzyme has been checked by SDS-PAGE and a single band has been detected corresponding to 78 kDa. IC₅₀ values, Ki values and inhibition types were found for some chems. on lactoperoxidase. Concentration range of chems. is 1.0-10.0 x 10^-6 M. The activity of asetophenone had very strong inhibitory effects with IC₅₀ values of 1.82 x 10^-6 M. Asetophenone was determined mixed type inhibition with 5.46 x 10^-6 M Ki value using 2,2′-Azinobis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) as a substrate. The enzyme was covalently immobilized onto a composite consisting of chitosan and gelatin biopolymers. The immobilization process was prepared on a glass substrate, a quartz crystal and an interdigitated electrode surface. This study will be a novel biosensor for based on measurements of pollutants, making it a selective and sensitive environmental pollutants in the water.

Fresenius Environmental Bulletin published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C15H12O6, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Balavoine, Gilbert published the artcileThio glycosides as potential glycosyl donors in electrochemical glycosidation reactions. Part 1. Their preparation and reactivity toward simple alcohols, Related Products of catalysis-chemistry, the publication is Journal of Carbohydrate Chemistry (1995), 14(8), 1217-36, database is CAplus.

Constant potential electrolysis of several glycosyl donors such as substituted Ph 2,3,4,6-tetra-O-acetyl, benzoyl or benzyl-1-thio-β-D-gluco or galactopyranosides in dry acetonitrile in the presence of various primary, secondary or tertiary alcs. performed in an undivided cell, gave preferentially β-linked saccharides in moderate to good yields according to the nature of the protective groups on the sugar moiety. 2-Deoxy-2-phthalimido-1-thio-β-D-gluco derivatives gave the β-glucosides selectively in excellent yields. It was found, as expected, that substitution of the Ph group with methoxy or Me radicals facilitates the electrochem. glycosidation reaction by lowering the oxidation potentials of the corresponding thio glycosides.

Journal of Carbohydrate Chemistry published new progress about 77189-99-2. 77189-99-2 belongs to catalysis-chemistry, auxiliary class Thiophenol,Benzene,Ether, name is 2,4,6-Trimethoxybenzenethiol, and the molecular formula is C9H12O3S, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Nivet, J. B. published the artcileSynthesis and bioacceptability of fluorinated surfactants derived from F-alkylated tertiary amines, COA of Formula: C10H6F17N, the publication is European Journal of Medicinal Chemistry (1992), 27(9), 891-8, database is CAplus.

Two methods for synthesizing tertiary F-alkylated amines are reported. The more general method allows the access in 56-87% yields to various N,N-dialkyl F-alkyl amines. These amines are key intermediates leading in 52-96% yields to several families of surfactants, including zwitterionic and cationic derivatives and amine oxides, potentially useful in the formulation of fluorocarbon emulsions for diagnostic and therapeutic uses. The toxicity of the new surfactants and the influence of the polar head were assessed: the long chain compounds C₈F₁₇(CH₂)₃N⁺Me₂(CH₂)_mCO₂^– (8; m = 3, 4, 5); C₈F₁₇(CH₂)₃N⁺R₃ X^– (9; R = Me, X = Cl; R = Et, X = Br) and C₈F₁₇(CH₂)₃NMe₂O were found to be toxic for cell cultures and the zwitterionic compounds, e.g., 8, have a LD₅₀ <250 mg·kg bw^-1 in mice. The hemolysis test highlights the influence of the polar head: the zwitterionic compounds were found to be non-hemolytic even at remarkably high concentrations (100 g L^-1 for 8), whereas the cationic compounds 9 are highly hemolytic even at very low concentrations (0.05 g L^-1).

European Journal of Medicinal Chemistry published new progress about 30670-30-5. 30670-30-5 belongs to catalysis-chemistry, auxiliary class Polyfluoroalkanes, name is 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-Heptadecafluorodecan-1-amine, and the molecular formula is C10H6F17N, COA of Formula: C10H6F17N.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Carraz, G. published the artcileBiochemical pharmacodynamics of the dipropylacetic acid structure, Application In Synthesis of 3115-28-4, the publication is Therapie (1965), 20(2), 419-26, database is CAplus.

Dipropylacetic acid (DPA) did not inhibit carbonic anhydrase nor did it change glutamine metabolism in rat brain. By using methylene blue as an electron acceptor, it was found that DPA, phenothiazines, and other neurotropic agents did not influence the oxidative pathway in guinea pig erythrocytes, which utilize mainly the pentose cycle for the metabolism of glucose. DPA and chlorpromazine did not interfere with anaerobic energy metabolism, but with the oxidative reactions in the glycolytic pathway. DPA and its derivatives interfered to varying degrees with the development of germinating wheat, which was accompanied by a strong depression of O consumption and the accumulation of glycolic acid. The depressing effects of DPA and its derivatives on germinating wheat were paralleled by their protective effects against cardiazole shock in the mouse.

Therapie published new progress about 3115-28-4. 3115-28-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is 2-Butylhexanoic acid, and the molecular formula is C10H20O2, Application In Synthesis of 3115-28-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Elumalai, Nagarajan published the artcileNanomolar Inhibitors of the Transcription Factor STAT5b with High Selectivity over STAT5a, Formula: C10H10O6, the publication is Angewandte Chemie, International Edition (2015), 54(16), 4758-4763, database is CAplus and MEDLINE.

Src homol. 2 (SH2) domains play a central role in signal transduction. Although many SH2 domains have been validated as drug targets, their structural similarity makes development of specific inhibitors difficult. The cancer-relevant transcription factors STAT5a and STAT5b are particularly challenging small-mol. targets because their SH2 domains are 93% identical on the amino acid level. Here the authors present the natural product-inspired development of the low-nanomolar inhibitor I, as the first small mol. which inhibits the STAT5b SH2 domain (K_i=44 nM) with more than 50-fold selectivity over STAT5a. The binding site of the core moiety of I was validated by functional anal. of point mutants. A prodrug of I was shown to inhibit STAT5b with high selectivity over STAT5a in tumor cells. I provides the first demonstration that naturally occurring SH2 domains with more than 90% sequence identity can be selectively targeted with small organic mols.

Angewandte Chemie, International Edition published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Formula: C10H10O6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Huckins, John R. published the artcileRh(III)-Catalyzed C-H Activation and Double Directing Group Strategy for the Regioselective Synthesis of Naphthyridinones, Synthetic Route of 1293990-73-4, the publication is Journal of the American Chemical Society (2013), 135(39), 14492-14495, database is CAplus and MEDLINE.

A general Rh-(III)-catalyzed synthesis of naphthyridinone derivatives is described. It relies on a double-activation and directing approach leveraging nicotinamide N-oxides as substrates. In general, high yields and selectivities can be achieved using low catalyst loadings and mild conditions (room temperature) in the couplings with alkynes, while alkenes require slightly more elevated temperatures

Journal of the American Chemical Society published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Synthetic Route of 1293990-73-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia