Tag: M.W=100-150

Zainab-L, Idris published the artcilePotential of mealworms used in polyhydroxyalkanoate/bioplastic recovery as red hybrid tilapia (Oreochromis sp.) feed ingredient, HPLC of Formula: 63-68-3, the publication is Scientific Reports (2022), 12(1), 9598, database is CAplus and MEDLINE.

Polyhydroxyalkanoates (PHAs) are bio-based polymers produced in bacterial cells to replace some petrochem. plastics. It has always been a challenge to commercialise PHA due in part to the costly recovery processes of the PHA granules from the bacterial cells. The biol. approach of using mealworms, Tenebrio molitor, for the recovery of PHA from the bacterial cells is a newly established method that is at the scale-up stage. On the other hand, the aquaculture feed industry needs a low-cost mealworm meal as a protein source. We aimed at studying the nutritional value of the mealworms (which are byproducts) used for the poly(3-hydroxybutyrate) (PHB) (the most common type of PHA) recovery from the bacterial and examining the effect of the mealworms on the growth performance, and feed utilization efficiency of red hybrid tilapia (Oreochromis sp.). The cells were fed to the mealworms to digest the proteinaceous cellular materials and excrete the PHB granules in the form of fecal pellets. The resulting mealworms were used as fishmeal replacement to formulate five isonitrogenous (35% crude protein) and isolipidic (8% lipid) diets at mealworm meal (MwM) inclusion levels of 0% (MwM0/control diet), 25% (MwM25), 50% (MwM50), 75% (MwM75) or 100% (MwM100). The results showed good nutritive value mealworms [high protein (75%), low-lipid (10%)] and up to 75% MwM inclusion diet was good in supplying satisfactory nutrients and energy to the red hybrid tilapia. This approach is beneficial in a way that minimal cost was involved in recovering kilograms of PHB and the proteins, lipids, and minerals from the bacterial cells do not end up as wastes but in turn, are used as nutrition by the larvae.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C10H15ClO3S, HPLC of Formula: 63-68-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tran, Trung Thien published the artcileEmergence of amoxicillin resistance and identification of novel mutations of the pbp1A gene in Helicobacter pylori in Vietnam, Product Details of C5H11NO2S, the publication is BMC Microbiology (2022), 22(1), 41, database is CAplus and MEDLINE.

Amoxicillin-resistant Helicobacter pylori (H. pylori) strains seem to have increased over time in Vietnam. This threatens the effectiveness of H. pylori eradication therapies with this antibiotic. This study aimed to investigate the prevalence of primary resistance of H. pylori to amoxicillin and to assess its association with pbp1A point mutations in Vietnamese patients. Naive patients who presented with dyspepsia undergoing upper gastrointestinal endoscopy were recruited. Rapid urease tests and PCR assays were used to diagnose H. pylori infection. Amoxicillin susceptibility was examined by E-tests. Mol. detection of the mutant pbp1A gene conferring amoxicillin resistance was carried out by real-time PCR followed by direct sequencing of the PCR products. Phylogenetic analyses were performed using the Tamura-Nei genetic distance model and the neighbor-joining tree building method. There were 308 patients (46.1% men and 53.9% women, p = 0.190) with H. pylori infection. The mean age of the patients was 40.5 ¡À 11.4 years, ranging from 18 to 74 years old. The E-test was used to determine the susceptibility to amoxicillin (min. inhibitory concentration (MIC) ¡Ü 0.125¦Ìg/mL) in 101 isolates, among which the rate of primarily resistant strains to amoxicillin was 25.7%. Then, 270 sequences of pbp1A gene fragments were analyzed. There were 77 amino acid substitution positions investigated, spanning amino acids 310-596, with the proportion varying from 0.4 to 100%. Seven amino acid changes were significantly different between amoxicillin-sensitive (Amox^S) and amoxicillin-resistant (Amox^R) samples, including Phe366 to Leu (p < 0.001), Ser₄₁₄ to Arg (p < 0.001), Glu/Asn_464-465 (p = 0.009), Val₄₆₉ to Met (p = 0.021), Phe₄₇₃ to Val (p < 0.001), Asp₄₇₉ to Glu (p = 0.044), and Ser/Ala/Gly_595-596 (p = 0.001). Phylogenetic analyses suggested that other mol. mechanisms might contribute to amoxicillin resistance in H. pylori in addition to the alterations in PBP1A. We reported the emergence of amoxicillin-resistant Helicobacter pylori strains in Vietnam and new mutations statistically associated with this antimicrobial resistance. Addnl. studies are necessary to identify the mechanisms contributing to this resistance in Vietnam.

BMC Microbiology published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C3H5BN2O2, Product Details of C5H11NO2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Grosso, John A. published the artcileSynthesis of 2-(alkylamino)-5,6- and -6,7-dihydroxy-3,4-dihydroquinazolines and evaluation as potential dopamine agonists, Application In Synthesis of 6972-05-0, the publication is Journal of Medicinal Chemistry (1982), 25(6), 703-8, database is CAplus and MEDLINE.

Based upon the known dopaminergic properties of 2-aminodihydroxy-1,2,3,4-tetrahydronaphthalenes, heterocyclic congeners were prepared Several 2-(alkylamino)-5,6-dihydroxy-3,4-dihydroquinazolines were synthesized and tested for a dopamine-like vasodilatory action in the canine renal artery. The 6,7-disubstituted series had a weak antagonist effect against dopamine. Neither 5,6- nor 6,7-dihydroxy substitution gave dopamine agonists. Measured pK_a values confirmed the expectation that the dihydroquinazolines were more basic than dopamine, one possible reason for the lack of dopamine-like action.

Journal of Medicinal Chemistry published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Application In Synthesis of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Goerdeler, Joachim published the artcileThioacyl isocyanates. XII. Preparation and comparison of aliphatic, aromatic and heteroaromatic compounds, Related Products of catalysis-chemistry, the publication is Chemische Berichte (1981), 114(2), 549-63, database is CAplus.

Dithiazolones I (R = Me, halomethyl, optionally substituted Ph, CH₂Ph, CO₂Et, CMe₃, CH:CHPh, NMe₂, pyridyl, 2-furyl, 5-methyl-3-isoxazolyl, 5-oxo-1,2,4-dithiazol-3-yl) were prepared by treating RCSNH₂ with ClCOSCl. II were similarly obtained from RCSNH₂ and ClCOCOCl. I and II eliminated S and CO resp. to give S:CRNCO. The latter compounds underwent cycloaddition reaction with imines, norbornene, and morpholinocyclohexene, as well as dimerization. S:CRNCO in which R is a strongly electron-attracting group are less reactive than others.

Chemische Berichte published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shibuya, Isao published the artcileThe synthesis of heteroaromatic cations containing sulfur or selenium atoms, Computed Properties of 6972-05-0, the publication is Bulletin of the Chemical Society of Japan (1987), 60(7), 2686-8, database is CAplus.

Oxidative cyclocondensation of Me₂NCCl:X⁺CClNMe₂ Cl^– (I; X = N, CH) with NaSH or NaSeH gave 43-95% heteroaromatic cations II (X = N, CH; X¹ = S, Se). Cyclocondensation of I with RCX¹NH₂ (R = Me₂N, Ph, pyrrolidino; X¹ = S, Se) gave 44-73% 6-membered heteroaromatic cations III.

Bulletin of the Chemical Society of Japan published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C19H17N2NaO4S, Computed Properties of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Otsuka, Masami published the artcileSynthesis, structure of copper(II) complexes of S-containing pentadentate ligands, Application In Synthesis of 6950-53-4, the publication is Journal of Organometallic Chemistry (2000), 611(1-2), 577-585, database is CAplus.

Novel ligands containing a pyridine and methylsulfanyl groups, 2,6-bis[(2-methylsulfanylethylamino)methyl]pyridine (4) and 2,6-bis[(2-methylsulfanylethylamino)methyl]-4-dimethylaminopyridine (7) were prepared and the properties of their copper complexes were studied. Potentiometric titration, absorption and ESR spectral measurements, and x-ray crystallog. of copper complexes of 4 and 7 were carried out. The x-ray structures of [Cu(4)](ClO₄)₂ and [Cu(7)](ClO₄)₂ revealed an intermediate geometry between the regular trigonal bipyramid with two secondary amines being axial and the regular square pyramid with one of the thioethers being in the apical position.

Journal of Organometallic Chemistry published new progress about 6950-53-4. 6950-53-4 belongs to catalysis-chemistry, auxiliary class Salt,sulfides,Amine,Aliphatic hydrocarbon chain, name is 2-(Methylthio)ethanamine hydrochloride, and the molecular formula is C3H10ClNS, Application In Synthesis of 6950-53-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Deng, Zhixin published the artcileLigand-enabled palladium-catalyzed hydroesterification of vinyl arenes with high linear selectivity to access 3-arylpropanoate esters, Name: 2-Methylbenzoic acid, the publication is Chemical Communications (Cambridge, United Kingdom) (2022), 58(24), 3921-3924, database is CAplus and MEDLINE.

Palladium-catalyzed linear-selective hydroesterification of vinyl arenes with alcs. enabled by diphosphine ligands derived from bis[2-(diphenylphosphino)ethyl]amides has been developed. A variety of 3-arylpropanoate esters were obtained in high yields and regioselectivity. The robustness of this methodol. was further demonstrated by the efficient gram-scale synthesis of the Et 3-phenylpropanoate as a precursor to hydrocinnamic acid.

Chemical Communications (Cambridge, United Kingdom) published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, Name: 2-Methylbenzoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Feilong published the artcileDecarboxylative amination of benzoic acids bearing electron-donating substituents and nonactivated amines, COA of Formula: C8H8O2, the publication is Organic Chemistry Frontiers (2022), 9(12), 3281-3292, database is CAplus.

A highly desirable and straightforward decarboxylative amination of readily available benzoic acids, with the long-inaccessible extension of decarboxylative amination to normally poorly reactive electron-rich benzoic acids and non-activated amines for synthesis of anilines RNR¹R² [R = 2-MeOC₆H₄, 2,6-di-MeC₆H₃, 2-methoxy-3-pyridyl, etc.; R¹ = H, Me; R² = Ph, Bn, 2-naphthyl, etc.; R¹R² = CH₂CH₂OCH₂CH₂] in moderate to high yields with excellent functional-group tolerance was reported. This aniline synthesis was applicable to a wide range of aryl/alkyl/heterocyclic amines under oxidant-free conditions, preventing adverse reactions compared to traditional methods. It also provided decarboxylative C-N modifications of complex bioactive nitrogen-bearing mols. to highlight the synthetic utility of this protocol. The theor. calculation had supported that this decarboxylative amination might proceeded via a concerted decarboxylation-iodination-type process to afford aryl iodine intermediates, which promoted a palladium-catalyzed C-N cross-coupling pathway under mild conditions. Notably, this efficient reaction featured a fine choice of the same base/solvent system to successfully achieve two independent reactions in a one-pot continuous operation process. This strategy provided a method for previously inaccessible decarboxylative amination of benzoic acids bearing electron-donating substituents, as a new alternative to the existing decarboxylative oxidative couplings.

Organic Chemistry Frontiers published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C5H5F3O2, COA of Formula: C8H8O2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

El-Wekil, Mohamed M. published the artcileAn innovative dual recognition aptasensor for specific detection of Staphylococcus aureus based on gold/iron oxide binary hybrid, Quality Control of 63-68-3, the publication is Scientific Reports (2022), 12(1), 12502, database is CAplus and MEDLINE.

Pathogenic bacteria cause disease outbreaks and threaten human health, prompting the research on advanced detection assays. Herein, we developed a selective mol. imprinted aptasensor for sensitive and prompt quantitation of Staphylococcus aureus (S. aureus) bacteria. The aptasensor was constructed by immobilization of aptamer on gold nanoparticles modified magnetic nanoparticles (apt-AuNPs@ Fe₃O₄). A functional monomer (o-phenylenediamine, o-phen) was electro-polymerized on the surface of the as-synthesized nanocomposite in the presence of a template (S. aureus). After removing S. aureus, the formed imprinted sites were available to extract pathogenic bacteria from complicated matrixes. The surface morphol. of the as-fabricated nanocomposites was characterized using different spectroscopic and electrochem. methods. Moreover, we thoroughly evaluated factors affecting the synthesis and determination procedures. The mol. imprinted aptasensor exhibited a wide linear range of 10¹-10⁷ CFU mL^-1 with a Limit of Detection, LOD (signal to noise = 3) of 1 CFU mL^-1. The aptasensor detected S. aureus in milk, conduit water, and apple juice samples with good recoveries % and satisfactory relative standard deviations (RSDs %) values.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Quality Control of 63-68-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Appleton, T. G. published the artcileComplexes with six-membered chelate rings. II. Proton magnetic resonance study of trimethylenediamine, some methyl-substituted derivatives, and their complexes with platinum(II) and palladium(II), Application of Propane-1,3-diamine dihydrochloride, the publication is Inorganic Chemistry (1970), 9(8), 1807-14, database is CAplus.

PMR spectra of compounds (diamine)(HCl)2, M(diamine)22+, and M(diamine)(NH3)22+ are reported, where M = Pt(II), Pd(II); diamine = trimethylenediamine, 2-methylpropane-1,3-diamine, pentane-2,4-diamine, neopentanediamine, ethylenediamine, meso-butane-2,3-diamine. These spectra are discussed in terms of the conformational behavior of the chelate rings. An unusual Pt-H coupling over 4 saturated bonds is observed in some complexes.

Inorganic Chemistry published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Application of Propane-1,3-diamine dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia