Tag: M.W=100-150

Singh, Vikramjeet published the artcileRedox noninnocence of the formazanate ligand applied to catalytic formation of ¦Á-ketoamides, Application In Synthesis of 118-90-1, the publication is Chemical Communications (Cambridge, United Kingdom) (2022), 58(46), 6630-6633, database is CAplus and MEDLINE.

An iron-formazanate mol. I (X = pyridine-1-yl) for efficiently preparing ¦Á-keto amides R(R¹)NC(O)R² [R = Me, Et, 2-(4-chlorophenyl)ethyl; R¹ = Et, Ph, 4-bromophenyl, etc.; RR¹ = -(CH₂)₄-, -(CH₂)₅-, -(CH₂)₂O(CH₂)₂-; R² = benzoyl, (thiophen-2-yl)carbonyl, cyclohexyl, etc.] is crucial reductive cleavage of the substrate mol. and tightly regulated by the electron donation from the formazanate, in a reversible manner.

Chemical Communications (Cambridge, United Kingdom) published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C36H45ClN3O8P, Application In Synthesis of 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Weis, Robert published the artcileSynthesis of new analogs of diphenylpyraline, Application In Synthesis of 6972-05-0, the publication is Tetrahedron (2003), 59(9), 1403-1411, database is CAplus.

1-Unsubstituted 4-dimethylamino-5,6-dihydropyridine-2(1H)-thiones were converted to isomeric piperidin-4-ols which were separated and N-methylated to 2-substituted 1-methylpiperidin-4-ols. Their 1-Ph analogs were prepared from 4-dimethylamino-5,6-dihydro-1-phenylpyridine-2(1H)-thiones. After their conversion to dihydro-1-phenylpyridin-4(1H)-ones the hydrogenation gave isomeric 1-phenylpiperidin-4-ols, which were separated O-Alkylation of the 1-substituted piperidin-4-ols by various methods yielded 2-substituted analogs of diphenylpyraline. Their antimycobacterial activity was examined The configurations and conformations of the piperidine derivatives were investigated by NMR spectroscopy.

Tetrahedron published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C18H35NO, Application In Synthesis of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Walter, Wolfgang published the artcileStructure of thioamides and their derivatives, XLII. N-(Trimethylsilyl)thioureas, HPLC of Formula: 6972-05-0, the publication is Liebigs Annalen der Chemie (1979), 263-77, database is CAplus.

N-silylation of mono- and disubstituted thioureas was carried out by treating them with Me₃SiCl/Et₃N. Monosilylated ureas could also be obtained from silylated amines and isothiocyanates. The trisubstituted thiourea Me₂NC(S)NHMe and monosilylated thioureas RNHC(S)NR¹SiMe₃ (R = Ph, R¹ = H, Ph; R = Me, R¹ = Ph) were silylated via metalation with BuLi and reaction with Me₃SiCl. Barriers to rotation about the C-N bond of the N-(trimethylsilyl)thioureas were determined

Liebigs Annalen der Chemie published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C17H37NO3, HPLC of Formula: 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Von Ohe, Peter C. published the artcileStructural Alerts-A New Classification Model to Discriminate Excess Toxicity from Narcotic Effect Levels of Organic Compounds in the Acute Daphnid Assay, SDS of cas: 6972-05-0, the publication is Chemical Research in Toxicology (2005), 18(3), 536-555, database is CAplus and MEDLINE.

Quant. and qual. structure-activity relationships (QSARs) have a great potential to support the risk assessment of chems., provided there are tools available that allow evaluation of the suitability of QSARs for the compounds of interest. In this context, a pragmatic approach is to discriminate excess toxicity from narcotic effect levels, because the latter can be estimated from QSARs and thus have a low priority for exptl. testing. To develop a resp. scheme for the acute daphnid toxicity as one of the primary ecotoxicol. endpoints, 1067 acute toxicity data entries for 380 chems. involving the daphnid species Daphnia magna were taken from the online literature, and quality checks such as water solubility were employed to eliminate apparently odd data entries. For 36 known narcotics with LC₅₀ values referring to D. magna, a reference baseline QSAR is derived. Compounds with LC₅₀ values above a certain threshold defined relative to their predicted baseline toxicity are classified as exerting excess toxicity. Three simple discrimination schemes are presented that enable the identification of excess toxicity from structural alerts based on the presence or absence of certain heteroatoms and their chem. functionality. Moreover, a two-step classification approach is introduced that enables a prioritization of organic compounds with respect to their need for exptl. testing. The discussion includes reaction mechanisms that may explain the association of structural alerts with excess toxicity, a comparison with predictions derived from mode of action-based classification schemes, and a statistical anal. of the discrimination performance in terms of detailed contingency table statistics.

Chemical Research in Toxicology published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C4H10O2, SDS of cas: 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Goehner, Martin published the artcile2,3-Dihydro-4,5-diisopropyl-1,3-dimethylimidazol-2-ylidene and its chalcogenones, Application In Synthesis of 6972-05-0, the publication is Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences (2015), 70(2), 91-94, database is CAplus.

2,3-Dihydro-4,5-diisopropyl-1,3-dimethylimidazol-2-ylidene (I) is prepared by reduction of the corresponding thione II with potassium. The selenium compound III is obtained from I and selenium. In the solid state, II and III exist as their isomers, as revealed by their crystal structures.

Zeitschrift fuer Naturforschung, B: A Journal of Chemical Sciences published new progress about 6972-05-0. 6972-05-0 belongs to catalysis-chemistry, auxiliary class Thiourea,Amine,Aliphatic hydrocarbon chain,Amide, name is 1,1-Dimethylthiourea, and the molecular formula is C3H8N2S, Application In Synthesis of 6972-05-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Hasegawa, Miki published the artcileElectronic structure of Cu(II) complexes with N,N’-disalicylidene-1,2-cyclohexanediamine and N,N’-disalicylidenetrimethylenediamine, Name: Propane-1,3-diamine dihydrochloride, the publication is Monatshefte fuer Chemie (2002), 133(3), 285-298, database is CAplus.

The electronic absorption and x-ray photoelectron spectra of N,N’-disalicylidenetrimethylenediaminatocopper(II) ([Cu(saltn)]) and N,N’-disalicylidene-trans-1,2-cyclohexanediaminatocopper(II) ([Cu(salchx)]) were measured. From these results and from informations derived from MO calculations the electronic structure of the complexes was clarified. Each electronic absorption band which can be assigned to the ¦Ð¦Ð^* or ML/LMCT transition of [Cu(saltn)] or [Cu(salchx)] observed in the wavelength region of 450-200 nm appears at the almost same frequency as the corresponding band of N,N’-disalicylideneethylenediaminatocopper(II) ([Cu(salen)]) in solution The LLCT bands (the intramol. CT band between two ¦Ð-electronic systems separated by saturated hydrocarbon chains such as -(CH₂)_n^–) also appear at nearly the same positions (?245 nm) for [Cu(salchx)], [Cu(saltn)], and [Cu(salen)]. The locations of the dd transition and the intensity of the ML/LMCT transition of [Cu(saltn)] are significantly different from those of [Cu(salen)] and [Cu(salchx)]. These differences may arise from the strengths of the interaction between metal and ligand.

Monatshefte fuer Chemie published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, Name: Propane-1,3-diamine dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zubkov, Mikhail O. published the artcilePhotocatalyzed Decarboxylative Thiolation of Carboxylic Acids Enabled by Fluorinated Disulfide, Application In Synthesis of 118-90-1, the publication is Organic Letters (2022), 24(12), 2354-2358, database is CAplus and MEDLINE.

Thiolation of carboxylic acids using a disulfide reagent having tetrafluoropyridinyl groups was described. The light-mediated process was performed using an acridine-type photocatalyst. Primary, secondary, tertiary and heteroatom-substituted carboxylic acids could be thiolated, and the method could be applied to the late-stage modification of a range of naturally occurring compounds and drugs. The fluorinated pyridine fragment was believed to enable the C-S bond formation. The resulting sulfides were used as redox-active radical precursors.

Organic Letters published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H6ClF3, Application In Synthesis of 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Furusawa, Yuka published the artcilePossibility of using the tips obtained from the “Uradome” of moso bamboo (Phyllostachys pubescens) as a food source, COA of Formula: C5H11NO2S, the publication is Journal of Wood Science (2022), 68(1), 23, database is CAplus.

In the cultivation of bamboo shoots in snow-covered areas, uradome is known to prevent snow damage. Although tips can be obtained by uradome, these are currently considered unutilized. Like bamboo shoots, uradome has the potential to be a source of food. Therefore, to explore the possibility of using uradome tips as food, we evaluated their egumi and umami taste, investigated the free amino acid content, and compared these parameters with those of bamboo shoots. The results showed that the egumi taste of uradome tips was weaker than that of bamboo shoots. The umami taste at first taste was weaker than that of bamboo shoots, while the umami and richness that remained after swallowing was stronger than that of bamboo shoots. The presence of a total of 18 free amino acids was evaluated in the uradome tips and bamboo shoots, and 17 free amino acids were detected in the samples, with cystine being the exception. Eleven of these free amino acids were found to be more abundant in the uradome tips. In addition, eight of the nine essential amino acids (excluding tryptophan) were found in the uradome tips and were in approx. the same amounts as in the bamboo shoots. Furthermore, leucine, a commonly known branched-chain amino acid, was present only in the uradome tips. Overall, the results suggest that uradome tips could be used as a food source.

Journal of Wood Science published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, COA of Formula: C5H11NO2S.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kouchi, Zen published the artcileFunction of SYDE C2-RhoGAP family as signaling hubs for neuronal development deduced by computational analysis, SDS of cas: 63-68-3, the publication is Scientific Reports (2022), 12(1), 4325, database is CAplus and MEDLINE.

Recent investigations of neurol. developmental disorders have revealed the Rho-family modulators such as Syde and its interactors as the candidate genes. Although the mammalian Syde proteins are reported to possess GTPase-accelerating activity for RhoA-family proteins, diverse species-specific substrate selectivities and binding partners have been described, presumably based on their evolutionary variance in the mol. organization. A comprehensive in silico anal. of Syde family proteins was performed to elucidate their mol. functions and neurodevelopmental networks. Predicted structural modeling of the RhoGAP domain may account for the mol. constraints to substrate specificity among Rho-family proteins. Deducing conserved binding motifs can extend the Syde interaction network and highlight diverse but Syde isoform-specific signaling pathways in neuronal homeostasis, differentiation, and synaptic plasticity from novel aspects of post-translational modification and proteolysis.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, SDS of cas: 63-68-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chimiak, A. published the artcileO-alkylhydroxylamines, Name: O-Isobutylhydroxylamine hydrochloride, the publication is Bulletin de l’Academie Polonaise des Sciences, Serie des Sciences Chimiques (1974), 22(3), 195-9, database is CAplus.

Thirteen RONH2 (R = C1-15 alkyl, PhCH2, p-O2NC6H4CH2) were prepared by alkylating N-hydroxyphthalimide to give N-alkoxyphthalimides, followed by hydrazinolysis. The alkylations were carried out with RI containing Na2CO3 or Et3N, with CH2N2, or with AcOCMe3-HCiO4.

Bulletin de l’Academie Polonaise des Sciences, Serie des Sciences Chimiques published new progress about 6084-58-8. 6084-58-8 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is O-Isobutylhydroxylamine hydrochloride, and the molecular formula is C4H12ClNO, Name: O-Isobutylhydroxylamine hydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia