Tag: M.W=200-250

Yost, Julianne M. published the artcileDirect carbon-carbon bond formation via soft enolization: aldol addition of α-halogenated thioesters, Application of 2,4,6-Triisopropylbenzenethiol, the publication is Chemical Communications (Cambridge, United Kingdom) (2011), 47(1), 571-572, database is CAplus and MEDLINE.

α-Halo thioesters undergo soft enolization and syn-selective direct aldol addition to aldehydes in the presence of MgBr₂·OEt₂ and i-Pr₂NEt to produce α-halo-β-hydroxy thioesters, e.g., I.

Chemical Communications (Cambridge, United Kingdom) published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C27H39ClN2, Application of 2,4,6-Triisopropylbenzenethiol.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rezaei, Fahimeh published the artcileDesign and synthesis of Fe₃O₄@SiO₂/aza-crown ether-Cu(II) as a novel and highly efficient magnetic nanocomposite catalyst for the synthesis of 1,2,3-triazoles, 1-substituted 1H-tetrazoles and 5-substituted 1H-tetrazoles in green solvents, HPLC of Formula: 5411-14-3, the publication is Inorganica Chimica Acta (2019), 8-18, database is CAplus.

A New and efficient magnetic nanocatalyst was fabricated via covalent grafting of an aza-crown ether Cu(II) complex on silica coated iron oxide support. The above mentioned magnetic nanocatalyst was characterized by various techniques such as SEM, TEM, XRD, FT-IR, TGA and ICP. After preparation, the applicability of this catalyst in the synthesis of triazole and tetrazole derivatives was studied. The prominent features of the present methodol. are: high yields, short reaction times, easy preparation, magnetical separation and favorable recoverability of the catalyst (for at least five runs without significant loss of catalytic activity).

Inorganica Chimica Acta published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, HPLC of Formula: 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kusurkar, Radhika S. published the artcileMicrowave-assisted conjugate addition of pyrrole on electron-deficient nitro-olefins, HPLC of Formula: 4230-93-7, the publication is Synthetic Communications (2010), 40(3), 320-327, database is CAplus.

Michael addition of pyrrole to β-nitrovinyl compounds were carried out using microwave methodol. Monosubstituted pyrroles were obtained selectively in a major amount Formation of novel product obtained during one of the reactions was explained by the double addition to nitrostyrene.

Synthetic Communications published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, HPLC of Formula: 4230-93-7.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Marcioni, Massimo published the artcileSemi-crystalline hydrophobic polyamidoamines: a new family of technological materials, COA of Formula: C16H20N2, the publication is Polymers (Basel, Switzerland) (2021), 13(7), 1018, database is CAplus and MEDLINE.

The hitherto known polyamidoamines (PAAs) are not suitable as structural materials because they are usually water-soluble or swellable in water. This paper deals with the synthesis and characterization of semi-crystalline hydrophobic PAAs (H-PAAs) by combining different bis-sec-amines with bis-acrylamides obtained from C6-C12 bis-prim-amines. H-PAAs were initially obtained in a solution of benzyl alc., a solvent suitable for both monomers and polymers. Their number average mol. weights, M_n, which were determined with ¹H-NMR by evaluating the percentage of their terminal units, varied from 6000 to >10,000. The solubility, thermal properties, ignitability and water resistance of H-PAAs were determined They were soluble in organic solvents, semi-crystalline and thermally stable. The most promising ones were also prepared using a bulk process, which has never been previously reported for PAA synthesis. In the form of films, these H-PAAs were apparently unaffected by water. The films underwent tensile and wettability tests. They showed similar Young moduli (260-263 MPa), whereas the maximum stress and the stress at break depended on the number of methylene groups of the starting bis-acrylamides. Their wettability was somewhat higher than that of common Nylons. Interestingly, none of the H-PAAs considered, either as films or powders, ignited after prolonged exposure to a methane flame.

Polymers (Basel, Switzerland) published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, COA of Formula: C16H20N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lin, Whei Oh published the artcileNeutral diamide ionophores – phenylenedioxybisacetamides, Safety of 2,2-(1,2-Phenylenebis(oxy))diacetic acid, the publication is Monatshefte fuer Chemie (1982), 113(1), 101-9, database is CAplus.

The title amides (I; R, R¹ = H, alkyl, aryl, cycloalkyl, NRR¹ = heterocycle containing optional O atom, etc.) were prepared I selectively chelated Group IIA cations by picrate extraction from water to CH₂Cl₂. This result was also confirmed by at. absorption measurement. The changes in UV absorption of aromatic rings and amide groups in the ligands upon titration with metal salts in methanol allowed an estimation of the ordering of cation binding.

Monatshefte fuer Chemie published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Safety of 2,2-(1,2-Phenylenebis(oxy))diacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Juvonen, Risto O. published the artcileDevelopment of new Coumarin-based profluorescent substrates for human cytochrome P450 enzymes, COA of Formula: C15H14O3, the publication is Xenobiotica (2019), 49(9), 1015-1024, database is CAplus and MEDLINE.

Cytochrome P 450 (CYP) enzymes constitute an essential xenobiotic metabolizing system that regulates the elimination of lipophilic compounds from the body. Convenient and affordable assays for CYP enzymes are important for assessing these metabolic pathways. In this study, 10 novel profluorescent coumarin derivatives with various substitutions at carbons 3, 6 and 7 were developed. Mol. modeling indicated that 3-phenylcoumarin offers an excellent scaffold for the development of selective substrate compounds for various human CYP forms, as they could be metabolized to fluorescent 7-hydroxycoumarin derivatives Oxidation of profluorescent coumarin derivatives to fluorescent metabolites by 13 important human liver xenobiotic-metabolizing CYP forms was determined by enzyme kinetic assays. Four of the coumarin derivatives were converted to fluorescent metabolites by CYP1 family enzymes, with 6-methoxy-3-(4-trifluoromethylphenyl)coumarin being oxidized selectively by CYP1A2 in human liver microsomes. Another set of four compounds were metabolized by CYP2A6 and CYP1 enzymes. 7-Methoxy-3-(3-methoxyphenyl)coumarin was oxidized efficiently by CYP2C19 and CYP2D6 in a non-selective fashion. The advantages of the novel substrates were (1) an excellent signal-to-background ratio, (2) selectivity for CYP1 forms, and (3) convenient multiwell plate measurement, allowing for precise determination of potential inhibitors of important human hepatic forms CYP1A2, CYP2C19 and CYP2D6.

Xenobiotica published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, COA of Formula: C15H14O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kitazawa, Makio published the artcileStudies on the synthesis of antiulcer agents. VI. Synthesis and antiulcer activity of dihydrobenzofuranone derivatives, Quality Control of 16909-09-4, the publication is Yakugaku Zasshi (1989), 109(10), 718-36, database is CAplus and MEDLINE.

Dimethyldihydrobenzofuranones I [R = OH, OEt, (un)substituted amino], II (R¹ = 5-, 6-, or 7-CH:CHCOR²; R² = piperidino, morpholino; R³ = 7-, 6-, or 5-OMe, Br, NO₂, NH₂, NHAc, H, Me, CO₂Et), III (n = 0-2; R⁴ = OH, OEt, substituted amino), and IV [R⁵ = (un)substituted amino] were prepared and tested for antiulcer activity. I (R = piperidino, morpholino) showed the highest activity.

Yakugaku Zasshi published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Quality Control of 16909-09-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yamaguchi, Shigehiro published the artcilePhotophysical Properties Changes Caused by Hypercoordination of Organosilicon Compounds: From Trianthrylfluorosilane to Trianthryldifluorosilicate, Recommanded Product: Difluorodiphenylsilane, the publication is Journal of the American Chemical Society (2000), 122(28), 6793-6794, database is CAplus.

Modification of π-electron systems by the main group elements represents a new direction toward the construction of organic materials with unusual electronic structures and with unique functions such as sensory materials. One of the potential way may be to take advantage of the hypercoordination abilities of the main-group elements. The authors present the first example of controlling the photophys. properties derived from the hypercoordination of group 14 elements. As a group 14 compound having extended π-conjugated substituents, tri(9-anthryl)fluorosilane (I) with its unique photophys. properties due to the through-space interaction was used. The addition of fluoride ion to I produced tri(9-anthryl)difluorosilicate (II). The use of KF/[2.2.2]cryptand as a fluoride source made possible to isolate the silicate cryptand (IIK⁺/cryptand) in 74% yield. Tetrahedral flat geometry crystal structure of I was changed due to hypercoordination to nearly ideal trigonal bipyramidal structure in IIK⁺/cryptand. The changes in the optical absorption and fluorescence spectra were studied by addition of n-Bu₄NF as a fluoride source to I. Upon formation of silicate IIBu₄⁺ fluorescence intensity increased with âˆ?0 nm hypsochromic shifts of the maximum, its absorption band was shifted into âˆ?0 nm shorter range relative to I. The observed changes should be mainly ascribed not to the intrinsic electronic perturbation by the hypercoordination but to the decrease in the degree of the through-space interaction between the anthryl groups by the structural change from tetrahedral of I to trigonal bipyramidal of II. The large spectral change of fluorescence spectra upon transition from from I to II allowed to estimate the binding constant of I toward fluoride as to be 2.8(±0.2) x 10⁴ M^-1 at 20° C in THF. Photophys. properties of series of similar triarylfluorosilanes and corresponding silicates were also studied.

Journal of the American Chemical Society published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C18H28N2O7, Recommanded Product: Difluorodiphenylsilane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yamaguchi, Shigehiro published the artcileEffect of Countercation Inclusion by [2.2.2]Cryptand upon Stabilization of Potassium Organofluorosilicates, Name: Difluorodiphenylsilane, the publication is Organometallics (1999), 18(15), 2851-2854, database is CAplus.

The reaction of organofluorosilanes with KF in the presence of [2.2.2]cryptand affords the corresponding organofluorosilicates with K⁺/[2.2.2]cryptand as the countercation. Not only diorganotrifluorosilicates, Ph₂SiF₃^–, but also triorganodifluorosilicates, Ph₃SiF₂^– and Ph₂MeSiF₂^–, were obtained as stable solids. The x-ray crystal structure analyses of these silicates show that three-dimensional inclusion of the K cation by cryptand prevents an interaction between the K atom and F atoms of the silicates. A comparison of the countercation between K⁺/[2.2.2]cryptand and K⁺/18-crown-6 reveals that the inclusion of the K cation by cryptand subtly facilitates the intramol. ligand exchange, as observed by the variable-temperature ¹⁹F NMR spectra.

Organometallics published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C19H34ClN, Name: Difluorodiphenylsilane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yamaguchi, Shigehiro published the artcileSynthesis, Structures, Photophysical Properties, and Dynamic Stereochemistry of Tri-9-anthrylsilane Derivatives, Product Details of C12H10F2Si, the publication is Organometallics (1998), 17(20), 4347-4352, database is CAplus.

Tri-9-anthrylsilanes having various substituents, such as -F, -H, -OH, -OMe, vinyl, and ethynyl, were prepared, and their UV-visible absorption and fluorescence spectra were determined Chiral propeller-like arrangements of three anthryl groups were confirmed by x-ray structural anal. of the fluoro and vinyl derivatives In solution, however, all the trianthrylsilanes prepared herein undergo enantiomerization at room temperature The free energies of enantiomerization are âˆ?-10 kcal mol^-1, determined by variable-temperature ¹H NMR. The propeller-like structure significantly reduces the quantum yield of fluorescence of the anthracene chromophore.

Organometallics published new progress about 312-40-3. 312-40-3 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Difluorodiphenylsilane, and the molecular formula is C19H34ClN, Product Details of C12H10F2Si.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia