Tag: M.W=200-250

Inaba, Masanori published the artcileNucleophilic fluoroalkylation/cyclization route to fluorinated phthalides, Name: Trimethyl(perfluorophenyl)silane, the publication is Beilstein Journal of Organic Chemistry (2018), 182-186, database is CAplus and MEDLINE.

A versatile and practical method for the synthesis of C3-perfluoroalkyl-substituted phthalides in a one-pot manner was described. Upon treatment of KF or triethylamine, 2-cyanobenzaldehyde reacted with (perfluoroalkyl)trimethylsilanes via nucleophilic addition and subsequent intramol. cyclization to give perfluoroalkylphthalides in good yields.

Beilstein Journal of Organic Chemistry published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Name: Trimethyl(perfluorophenyl)silane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Yasukawa, Tomohiro published the artcileHomologation of Aryl Aldehydes Using Nitromethane as a C1 Source Enabled by Nitrogen-Doped Carbon-Supported Palladium Catalysts, Safety of 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, the publication is ACS Catalysis (2022), 12(10), 5887-5893, database is CAplus.

Homologation of aryl aldehydes provides useful synthetic intermediates, but it requires multistep reactions and generates significant amounts of waste. Herein, such reactions using nitromethane as a C1 source through nitroolefin formation, partial hydrogenation to oximes, and hydration of oximes were considered; however, the control of selectivity in the second reaction was challenging. To achieve this pathway, nitrogen-doped carbon-incarcerated palladium nanoparticle catalysts were developed for selective hydrogenation. The presence of nitrogen dopants effectively tuned the catalytic activity to show almost perfect selectivity, high activity, and reusability under ambient pressure. Then a three-step homologation reaction was performed in both batch and flow systems with only one purification step. The sequential continuous-flow system worked efficiently for more than 2 days to afforded the product in a high yield.

ACS Catalysis published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C11H10ClNO, Safety of 1,2-Dimethoxy-4-(2-nitrovinyl)benzene.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Usui, Shinnosuke published the artcileThe effect of grade of quartz on the cationic flotation of quartz from hematite, Recommanded Product: Dodecylamineacetate, the publication is Tohoku Daigaku Senko Seiren Kenkyusho Iho (1980), 36(1), 17-22, database is CAplus.

Flotation experiments were carried out with quartz [14808-60-7] and hematite [1317-60-8] (44-53 ¦Ì), sep. and mixed, using a Denver-type laboratory floatator, at various values of pH and collector (dodecyl ammonium acetate DAA [2016-56-0]) concentration, with special reference to the effect of the grade of quartz on the reverse flotation of quartz. The individual flotation indicated that complete flotation of quartz was obtained at a DAA concentration of (5 ¡Á 10^-5)-(1 ¡Á 10^-4)M (0.25-0.5 kg/ton) and at pH 5-5.4, midpoint of isoelec. points of resp. minerals, while no flotation of hematite took place under corresponding conditions. In the flotation of the mixed sample an incomplete separation was obtained under the same conditions; the floatability of quartz decreased while that of hematite increased. The floatability of quartz decreased with decrease in grade, indicating that the reverse flotation of low-grade quartz from hematite becomes difficult. The poor separation of quartz described above was improved considerably by the addition of 1 ¡Á 10^-4M sodium gluconate [527-07-1].

Tohoku Daigaku Senko Seiren Kenkyusho Iho published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H10O4, Recommanded Product: Dodecylamineacetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Iancu, Gabriela Mariana published the artcileEvolution of syphilis incidence in Sibiu county (Romania) over a period of 10 years (2009-2018), HPLC of Formula: 140-28-3, the publication is Experimental and Therapeutic Medicine (2021), 22(2), 803, database is CAplus and MEDLINE.

Syphilis is the most common sexually transmitted disease that mainly affects socially active people, with a fluctuating worldwide incidence over the years. A retrospective study was conducted over a period of 10 years (2009-2018) that included 396 patients with syphilis diagnosed and monitored by Sibiu County Emergency Clin. Hospital, Romania. During this period (2009-2018), we observed a decrease in the new cases of syphilis by 35.90%, and the average syphilis incidence was 9.90 new cases per 100,000 inhabitants. Syphilis was diagnosed more frequently in men with an average age of 35.39 years, from urban areas, with and educational level of grades 9-12, unmarried, workers, or without occupation. Out of the 396 patients with syphilis, about 6% were HIV coinfected. Over half of the HIV coinfected cases were declared MSM (men who have sex with men), and 40% of these cases were registered in 2018. The most common clin. stage of syphilis was the latent form (67.93%). Regarding the syphilis treatment regimen, we noted the transition from the classic regimen with benzathine-penicillin G (100% in 2009) to alternative therapies (mainly with cephalosporins) in 2018 (56.86%). Our findings showed that in the last 10 years in our county, the incidence of syphilis had a downward trend, but with an increase in syphilis-HIV co-infection and neurosyphilis cases.

Experimental and Therapeutic Medicine published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, HPLC of Formula: 140-28-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Talotta, Carmen published the artcileSynthesis and supramolecular features of hybrid POM/onium solid-state assemblies, COA of Formula: C16H20N2, the publication is Supramolecular Chemistry (2016), 28(5-6), 403-417, database is CAplus.

Polyoxomolybdate-based organic-inorganic hybrid architectures were synthesized and characterized by x-ray crystallog. The supramol. assemblies present rows of metallic clusters H-bonded by ammonium cations, with a 1:2 molybdate/ammonium ratio. The organic moieties of the ammonium cations establish hydrophobic contact among them such as van der Waals, C-H¡¤¡¤¡¤¦Ð and ¦Ð¡¤¡¤¡¤¦Ð interactions that stabilize the supramol. architectures. In particular, for compound (5) the n-alkyl tails pack closely together giving a lipid-like bilayer. In compound (6), the aromatic Ph rings of the organic cation allow the stabilization of the supramol. architecture by C-H¡¤¡¤¡¤¦Ð and ¦Ð¡¤¡¤¡¤¦Ð interactions. Regarding the x-ray structure of the compound (11), the tetraanionic octa-molybdate [Mo₈O₂₆]^4- cluster is surrounded by four Et-triphenyl-phosphonium cations. Running along the b-axis open channels are occupied by DMF solvent mols. A soaking experiment in n-pentane with the corresponding crystals of compound 11 afforded a crystal structure very different from the native one.

Supramolecular Chemistry published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C5H6BNO2, COA of Formula: C16H20N2.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Disadee, Wannaporn published the artcileOne-pot cascade synthesis of azabicycles via the nitro-Mannich reaction and N-alkylation, Category: catalysis-chemistry, the publication is Organic & Biomolecular Chemistry (2018), 16(5), 707-711, database is CAplus and MEDLINE.

A one-pot, metal-free process for the synthesis of azabicycles is developed. The key transformations involved a cascade of double intramol. cyclizations via the nitro-Mannich reaction and N-alkylation, providing various ring systems of azabicycles in yields up to 81% and an isomeric ratio of 62 : 1. This approach offers considerable advantages in terms of the handling of small mols., the flexibility to introduce a functionalized side chain, and gives direct access to various azabicycles.

Organic & Biomolecular Chemistry published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Category: catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

MacDonnell, Frederick M. published the artcileSterically Encumbered Iron(II) Thiolate Complexes: Synthesis and Structure of Trigonal Planar [Fe(SR)₃]^– (R = 2,4,6-t-Bu₃C₆H₂) and Moessbauer Spectra of Two- and Three-Coordinate Complexes, Related Products of catalysis-chemistry, the publication is Inorganic Chemistry (1995), 34(7), 1815-22, database is CAplus.

The synthesis and structural characterization of three compounds containing three-coordinate Fe(II) and stabilized by sterically encumbered thiolate ligands are reported. Reaction of [Fe₂(SC₆H₂-2,4,6-t-Bu₃)₄] (3) with LiSC₆H₂-2,4,6-t-Bu₃ in ether/THF/hexane afforded [Li(THF)₂(5)]¡¤0.5C₆H₁₄ (5 = [Fe(SC₆H₂-2,4,6-t-Bu₃)₃]^–). Addition of Ph₄PCl to a reaction mixture in toluene followed by recrystallization of the product from MeCN yielded (Ph₄P)[5]¡¤2MeCN¡¤C₇H₈. [Fe₃(SC₆H₂-2,4,6-i-Pr₃)₄(N(SiMe₃)₂)₂] was prepared by the reaction of [Fe(N(SiMe₃)₂)₂] (6) with the thiol in toluene. [Li(THF)₂(5)]¡¤0.5C₆H₁₄ crystallizes in monoclinic space group P2₁/c with a 9.809(2), b 22.507(5), c 29.553(5) ?, ¦Â 95.72(2)¡ã, and Z = 4 (130 K). (Ph₄P)[5]¡¤2MeCN¡¤C₇H₈ was obtained in monoclinic space group P2₁ with a 17.538(5), b 14.912(4), c 17.608(5) ?, ¦Â 115.71(3)¡ã, and Z = 2 (143 K). These compounds contain the 1st example of mononuclear Fe(II) in a close approach to a trigonal planar [5] or a distorted trigonal planar [Li(THF)₂(5)] S coordination environment. In the Ph₄P salt, [5] exhibits the mean values Fe-S = 2.274(9) ? and S-Fe-S = 120(3)¡ã, while in [Li(THF)₂(5)] the Li⁺ ion bridges two S atoms, causing a lengthening (0.06-0.07 ?) of the Fe-S bridged bond lengths and constriction of the bridged S-Fe-S angle (92.2(1)¡ã). Compound 6 crystallizes in space group P2₁/c with a 14.521(5), b 41.60(2), c 14.241(4) ?, ¦Â 100.42(2)¡ã, and Z = 4 (130 K). The structure has a linear Fe₃(¦Ì₂-SR)₄ fragment with an almost linear Fe₃ array involving the central Fe(II) atom in a severely distorted tetrahedral environment; the terminal Fe(II) atoms are three-coordinate and planar with terminal N(SiMe₃)₂ ligands. Complex 5 expands the family of homoleptic mol. Fe(II) thiolates to five structural types; complexes 5 and 6 with two previously reported species [Fe₂(SR)₄] constitute the known examples of three-coordinate Fe^II with partial or complete S ligation. The zero-field Moessbauer spectra of examples of the five types of homoleptic Fe(II) thiolates are reported together with several tetrahedral complexes having Fe^II-S/SR coordination to determine what structural distinctions could be made from isomer shifts and quadrupole splittings. From the limited data set, it is tentatively concluded that trigonal planar Fe^II(SR)₃ can be distinguished from tetrahedral Fe^II(SR)₄ and Fe^II-S/SR units from its smaller quadrupole splitting (0.81 mm/s for 5 at 4.2-100 K).

Inorganic Chemistry published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wehmschulte, Rudolf J. published the artcileSynthesis and Structure of Unassociated Mono-, Di- and Trithiolate Derivatives of Aluminum and Gallium: Investigation of Al-S and Ga-S ¦Ð-Bonding, Application of 2,4,6-Triisopropylbenzenethiol, the publication is Inorganic Chemistry (1995), 34(10), 2593-9, database is CAplus.

The synthesis and characterization of several sterically crowded Al and Ga thiolates are described. The major reason for these studies was the study of the possible occurrence of ¦Ð-bonding in Al-S and Ga-S bonds and the determination of the steric requirements for the isolation of monomeric heavier main Group 3 thiolates in the solid state. The compounds examined were RAl(SMes^*)₂ (R = Bu, 1; t-Bu, 2), Mes^*₂GaSR (Mes^* = 2,4,6-t-Bu₃C₆H₂, R = Me,3; Ph, 4), BuGa(SMes^*)₂, (5) (t-Bu₂AlSTrip)₂ (6) (Trip = 2,4,6-i-Pr₃C₆H₂), (THF)Al(STrip)₃ (7). They were characterized by x-ray crystallog. (1–3, 5–7) and by NMR and IR spectroscopy. The M-S, p-p, ¦Ð-bonding is weak and has an upper limit of 8-9 kcal mol^-1. Restricted rotation around an M-S bond was detected only in the cases of 3 and 4. Crystal data at 130 K with Mo K¦Á (¦Ë = 0.710 69 ?) (2, 5–7) or Cu K¦Á (¦Ë = 1.541 78 ?) (1, 3) radiation; 1, C₄₀H₆₇AlS₂, a 18.563(5), b 27.171(11), c 32.089(4) ?, orthorhombic, Z = 16 (two independent mols.), space group Pbca, R = 0.087 for 6746 (I > 2¦Ò(I)) reflections; 2, C₄₀H₆₇AlS₂, a 17.375(9), b 27.982(10), c 17.868(8) ?, ¦Â 112.29(2)¡ã, Z = 8 (two independent mols.), monoclinic, space group P2₁/c, R = 0.082 for 8425 (I > 2¦Ò(I)) reflections; 3, C₃₇H₆₁GaS, a 33.654(8), b 10.433(4), c 20.258(8) ?, Z = 8, orthorhombic, space group Pbcn, R = 0.066 for 3164 (I > 2¦Ò(I)) reflections; 5, C₄₀H₆₇GaS₂, a 18.521(8), b 27.342(10), c 32.046(12) ?, orthorhombic, Z = 16 (two independent mols.), space group Pbca, R = 0.144 for 3297 (I > 2¦Ò(I)) reflections; 6, C₄₆H₈₂Al₂S₂, a 20.820(8), b 14.598(6), c 16.118(4) ?, Z = 4, orthorhombic, space group Pna2₁, R = 0.062 for 2469 (I > 2.5¦Ò(I)) reflections; 7, (THF)Al(STrip)₃¡¤0.5C₆H₁₄, C₅₂H₈₄AlOS₃, a 15.589(6), b 13.622(5), c 26.308(12) ?, ¦Â 99.88(4)¡ã, Z = 4, monoclinic, space group P2₁/c, R = 0.075 for 5697 (I > 3¦Ò(I)) reflections.

Inorganic Chemistry published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C18H23N3O4S, Application of 2,4,6-Triisopropylbenzenethiol.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Peterson, John R. published the artcileSynthesis and experimental ionization energies of certain (E)-3-arylpropenoic acids and their methyl esters, Formula: C11H12O4, the publication is Journal of Chemical and Engineering Data (1988), 33(4), 534-7, database is CAplus.

Ionization energies for methoxy-substituted (E)-3-arylpropenoic acids and Me (E)-3-arylpropenoates were exptl. determined by mass spectroscopy. The title compounds were prepared in excellent yield by Knoevenagel condensation of an aromatic aldehyde with malonic acid and by Fischer esterification of the acid with methanol.

Journal of Chemical and Engineering Data published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Formula: C11H12O4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Shin, Jai Moo published the artcile1-arylsulfonyl-2-(pyridylmethylsulfinyl) benzimidazoles as new proton pump inhibitor prodrugs, Recommanded Product: 2,2-(1,2-Phenylenebis(oxy))diacetic acid, the publication is Molecules (2009), 14(12), 5247-5280, database is CAplus and MEDLINE.

New arylsulfonyl proton pump inhibitor (PPI) prodrug forms were synthesized. These prodrugs provided longer residence time of an effective PPI plasma concentration, resulting in better gastric acid inhibition.

Molecules published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C19H21N3O3S, Recommanded Product: 2,2-(1,2-Phenylenebis(oxy))diacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia