Tag: M.W=200-250

Angapelly, Srinivas published the artcileDevelopment of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors, Formula: C11H12O4, the publication is Bioorganic & Medicinal Chemistry (2017), 25(20), 5726-5732, database is CAplus and MEDLINE.

A series of novel sulfonamides incorporating phenylacrylamido functionalities were synthesized and investigated for the inhibition of the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1). The physiol. and pharmacol. relevant human (h) isoforms hCA I and II (cytosolic isoenzymes), as well as the transmembrane tumor-associated hCA IX and XII were included in the study. These compounds showed low nanomolar or sub-nanomolar inhibition constants against hCA II (K_Is in the range of 0.50-50.5 nM), hCA IX (K_Is of 1.8-228.5 nM), and hCA XII (K_Is of 3.5-96.2 nM) being less effective as inhibitors of the off target isoform hCA I. A detailed structure-activity relationship study demonstrates that the nature and position of substituents present on the aromatic part of the scaffold strongly influence the inhibition of CA isoforms. As hCA II, IX and XII are involved in pathologies such as glaucoma and hypoxic, and metastatic tumors, compounds of the type reported may be useful preclin. candidates.

Bioorganic & Medicinal Chemistry published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Formula: C11H12O4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lin, Qing-Yu published the artcilePhotoredox-Catalyzed Bromodifluoromethylation of Alkenes with (Difluoromethyl)triphenylphosphonium Bromide, Formula: C15H15OP, the publication is Organic Letters (2016), 18(10), 2419-2422, database is CAplus and MEDLINE.

Under visible-light photoredox conditions, difluoromethyltriphenylphosphonium bromide was used as the precursor of the CF₂H radical for bromodifluoromethylation of alkenes. The presence of catalytic CuBr₂ resulted in the selective formation of the bromodifluoromethylated products. Also, the alkenes underwent bromodifluoromethylation followed by dehydrobromination to give the difluoromethylated alkenes in good yields.

Organic Letters published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Formula: C15H15OP.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kumar, Tulam Vijaya published the artcilePolyethylene glycol (PEG-400) as an efficient and recyclable reaction medium for one-pot synthesis of substituted pyrroles under catalyst-free conditions, Application In Synthesis of 4230-93-7, the publication is Asian Journal of Chemistry (2015), 27(4), 1457-1461, database is CAplus.

Polyethylene glycol (PEG 400) was found to be an effective non-toxic reaction medium for multicomponent synthesis of substituted pyrroles I [R¹ = Ph, benzyl, 3-FC₆H₄, etc.; R² = 2-Br, 3,4-(OMe)₂, H, etc.] via tandem Michael addition-cyclization of amines, nitrostyrenes and acetylacetone. Environmental acceptability, low cost, high yields and recyclability of polyethylene glycol were important advantages of this protocol.

Asian Journal of Chemistry published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Application In Synthesis of 4230-93-7.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chernyshova, I. V. published the artcileMechanism of Adsorption of Long-Chain Alkylamines on Silicates. A Spectroscopic Study. 1. Quartz, Computed Properties of 2016-56-0, the publication is Langmuir (2000), 16(21), 8071-8084, database is CAplus.

The mechanism of adsorption of long-chain alkylamines at pH 6-7 onto quartz was studied using FTIR and XPS spectroscopy. The spectroscopic data were correlated with ¦Æ potential and Hallimond flotation results. For the 1st time (1) amine cation in the 1st monolayer is H-bonded with surface silanol group and this H-bond becomes stronger after the break in the adsorption characteristics (isotherm, ¦Æ potential, floatability); (2) at the break the origin of the adsorbed amine species changes qual., and along with alkylammonium ion attached to deprotonated silanol group, mol. amine appears at the surface and, as a result, monolayer thick patches of well-oriented and densely packed adsorbed amine species form rendering the surface highly hydrophobic; and (3) at higher amine concentration, bulk precipitation of mol. amine takes place. The counterion influences both these steps. A model of successive two-dimensional and three-dimensional precipitation was suggested to explain amine adsorption on a silicate surface.

Langmuir published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, Computed Properties of 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Chernyshova, I. V. published the artcileMechanism of adsorption of long-chain alkylamines on silicates: A spectroscopic study. 2. Albite, SDS of cas: 2016-56-0, the publication is Langmuir (2001), 17(3), 775-785, database is CAplus.

Using FTIR (DRIFTS and IRRAS) and XPS spectroscopy, ¦Æ potential measurements, and Hallimond flotation tests, it was confirmed that long-chain primary amines are adsorbed on silicates at pH 6-7 through the 2D-3D precipitation mechanism. The orientation and packing of dodecyl- and hexadecylammonium acetate and chloride adsorbed on albite in the different regions of the adsorption isotherm were determined These characteristics depend strongly on the substrate. Coadsorption of the counterion was not revealed, but the counterion was found to affect indirectly the adsorption at concentrations above the concentration of the bulk amine precipitation

Langmuir published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C14H31NO2, SDS of cas: 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Vidyadhar, A. published the artcileMechanisms of amine-feldspar interaction in the absence and presence of alcohols studied by spectroscopic methods, Application In Synthesis of 2016-56-0, the publication is Colloids and Surfaces, A: Physicochemical and Engineering Aspects (2003), 214(1-3), 127-142, database is CAplus.

The adsorption of long-chain primary amines on feldspars at neutral pH 6-7 was investigated using Hallimond flotation, zeta-potential, FT-IR and XPS studies. Two-dimensional (2D) followed by three-dimensional (3D) precipitation mechanism of amine adsorption on quartz reported earlier (Langmuir 16 (2000) 8071) was further substantiated. The orientation and packing of dodecyl- and hexadecylammonium acetate and chloride adsorbed on albite in the different regions of the adsorption isotherm were determined It was shown that these characteristics depend strongly on the substrate. The influence of long-chain alcs. on the adsorption of amines in mixed amine/alc. on feldspars, i.e. albite (NaAlSi₃O₈) and microcline (KAlSi₃O₈), was also examined Coadsorption of the counterion was not revealed, but the counterion was found to affect indirectly the adsorption at concentrations above the concentration of the bulk amine precipitation It was proved spectroscopically that co-adsorption of long-chain alcs. along with amine cations leads to formation of a closed packed surface layer as compared to the case of adsorption of pure amine alone at the same concentration The highest order and packing at the surface were observed when the alkyl chain length of mixed amine and alc. were the same. The condition of same chain length of amines and alcs. adsorbing at the surface corresponded to maximum flotation recovery. The results also confirmed the synergistic enhancement of amine adsorption in the presence of alcs. A mechanism of mixed long-chain amine and alc. adsorption onto silicates (albite and quartz) consistent with the primary adsorption species of alkylammonium-water-alc. complex, where deprotonation of ammonium groups in the adsorbed layer leading to 2D precipitation of mol. amine was illustrated.

Colloids and Surfaces, A: Physicochemical and Engineering Aspects published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C12H15ClO3, Application In Synthesis of 2016-56-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Vidyadhar, A. published the artcileMechanisms of Amine-Quartz Interaction in the Absence and Presence of Alcohols Studied by Spectroscopic Methods, Recommanded Product: Dodecylamineacetate, the publication is Journal of Colloid and Interface Science (2002), 256(1), 59-72, database is CAplus.

The adsorption mechanism of long-chain alkylamines and their acetate salts on quartz was investigated using Hallimond flotation, zeta-potential, Fourier transform IR, and XPS studies at neutral pH 6-7. The influence of long-chain alcs. on the adsorption of amines in mixed amine-alc. on quartz was also examined It is shown by IR spectroscopy that in differentiation to the electrostatic adsorption model of Gaudin-Fuerstenau-Somasundaran, amine cations form strong hydrogen bonds with the surface silanol groups. The XPS spectra revealed the presence of neutral amine mols. together with protonated ammonium ions at and above the critical hemimicelle concentration The acetate counterions were found to influence the amine adsorption. Possible mechanisms of adsorption based on these observations were discussed. For the first time it was proved spectroscopically that coadsorption of long-chain alcs. along with amine cations leads to formation of a closely packed surface layer, as compared to the case of adsorption of pure amine alone at the same concentration The highest order and packing at the surface are observed when the alkyl chain length of mixed amine and alc. are the same. The condition of same chain length of amines and alcs. adsorbing at the surface corresponds to maximum flotation recovery. The results also confirmed the synergistic enhancement of amine adsorption in the presence of alcs. The mechanism for mixed long-chain amine and alc. adsorption onto quartz is consistent with the primary adsorption species of alkylammonium-water-alc. complex, where deprotonation of ammonium groups in the adsorbed layer leading to two-dimensional precipitation of mol. amine was illustrated.

Journal of Colloid and Interface Science published new progress about 2016-56-0. 2016-56-0 belongs to catalysis-chemistry, auxiliary class Active Esterification, name is Dodecylamineacetate, and the molecular formula is C44H28ClFeN4, Recommanded Product: Dodecylamineacetate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Slitikov, P. V. published the artcileAminomethylation of naphthalen-2-ol and naphthalene-2,7-diol, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine, the publication is Russian Journal of Organic Chemistry (2016), 52(10), 1432-1435, database is CAplus.

Reactions of secondary aliphatic and heterocyclic diamines with formaldehyde and naphthalen-2-ol or naphthalene-2,7-diol afforded the corresponding Mannich bases I (R = H, OH; X = (CH₂)₂, (CH₂)₃; R¹ = CH₃, C₂H₅,CH₂C₆H₅). The formation of strong intramol. hydrogen bonds O-H ¡¤ ¡¤ ¡¤ N in the mols. of some products was detected by IR and ¹H NMR spectroscopy.

Russian Journal of Organic Chemistry published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C6H10O3, Recommanded Product: N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Rajakumar, Perumal published the artcileSynthesis, characterization and ion transportation studies of some novel cyclophane amides, Name: 2,2-(1,2-Phenylenebis(oxy))diacetic acid, the publication is Tetrahedron (2005), 61(22), 5351-5362, database is CAplus.

Various cyclophane amides with a large cavity have been synthesized. The structures of cyclophane amides I and II and were resolved using XRD studies. Cyclophane amide III shows a shift in ¦Ë_max in the UV/Vis. spectra when treated with Cu(II) ion as well as with Pb(II) ion. Ion transportation studies were carried out with cyclophane amide I which proved that the Na⁺ ion passes through the cavity while K⁺ ions are retained.

Tetrahedron published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Name: 2,2-(1,2-Phenylenebis(oxy))diacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Namera, Dipti L. published the artcileMicrowave assisted synthesis of 2,5-distyryl-1,3,4-oxadiazole derivatives as antimicrobial agents, Application In Synthesis of 16909-09-4, the publication is International Letters of Chemistry, Physics and Astronomy (2014), 46-54, 9 pp., database is CAplus.

A new series of 2,5-distyryl-1,3,4-oxadiazoles derivatives have been synthesized from cinnamic hydrazide on reaction with various cinnamic acid derivatives The structures of synthesized compounds have been elucidated by spectral studies like IR, 1HNMR, Mass and also Elemental Anal. Furthermore, all synthesized compounds were screened for in vitro anti microbial activity against the gram pos. (Staphylococcus aureus, Pseudomonas aeruginosa) and gram neg. (Escherichia coli) bacterial strain. In which some the compounds show potential inhibition against the test organisms.

International Letters of Chemistry, Physics and Astronomy published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Application In Synthesis of 16909-09-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia