Month: December 2022

Bark, L. S. published the artcileThe effect of substituent groupings on the chromatographic behavior of phenoxyacetic acids. II. Chloro-substituted phenoxyacetic acids, Related Products of catalysis-chemistry, the publication is Analyst (1960), 905-7, database is CAplus.

Twelve chloro-substituted phenoxyacetic acids (2-, 3-, and 4-chloro, 2,3-, 2,4-, 2,5-, 2,6-, 3,4- and 3,5-dichloro, 2,4,5- and 2,4,6-trichloro) were studied. The acid can be adsorbed on paper by attachment of both the acid group and the substituent group to the cellulose, the substituent being attached by H bonding between the OH groups of the cellulose and the electroneg. atom of the substituent. The relatively low adsorption of acids substituted in both the 2 and 6 positions is probably caused by restriction of rotation of the phenoxyacetic acid grouping, resulting in attachment by this group only.

Analyst published new progress about 1798-04-5. 1798-04-5 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(4-(tert-Butyl)phenoxy)acetic acid, and the molecular formula is C12H16O3, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhu, Qilei published the artcileIntermolecular Anti-Markovnikov Hydroamination of Unactivated Alkenes with Sulfonamides Enabled by Proton-Coupled Electron Transfer, Application In Synthesis of 22693-41-0, the publication is Journal of the American Chemical Society (2018), 140(2), 741-747, database is CAplus and MEDLINE.

Here authors report a catalytic method for the intermol. anti-Markovnikov hydroamination of unactivated alkenes using primary and secondary sulfonamides. These reactions occur at room temperature under visible light irradiation and are jointly catalyzed by an iridium(III) photocatalyst, a dialkyl phosphate base, and a thiol hydrogen atom donor. Reaction outcomes are consistent with the intermediacy of an N-centered sulfonamidyl radical generated via proton-coupled electron transfer activation of the sulfonamide N-H bond. Studies outlining the synthetic scope (>60 examples) and mechanistic features of the reaction are presented.

Journal of the American Chemical Society published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C22H12F6O6S2, Application In Synthesis of 22693-41-0.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Bisaro, F. published the artcileCross-metathesis, a versatile synthetic methodology for the construction of alkenyl phosphine oxides and bis-phosphine oxides, Computed Properties of 4141-48-4, the publication is Tetrahedron Letters (2003), 44(38), 7133-7135, database is CAplus.

Substituted vinyl and allyl phosphine oxides were prepared by olefin cross-metathesis providing exclusive E olefin stereochem. The methodol. was successfully extended to the preparation of various bis-phosphine oxides.

Tetrahedron Letters published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Computed Properties of 4141-48-4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Joshi, Raman Kumar published the artcileRadiosynthesis challenges of ¹¹C and ¹⁸F-labeled radiotracers in the FX2C/N tracerlab and their validation through PET-MR imaging, Formula: C17H37NO3, the publication is Applied Radiation and Isotopes (2021), 109486, database is CAplus and MEDLINE.

Glucose is the renowned source of the energy for the cancer growth, that¡äs the reason for [¹⁸F]FDG success and make it widely used radiotracer. Though [¹⁸F]FDG has its own inherent limitations therefore many tracers have been developed to target specific receptors, and other metabolic routes. We have used FX2C and FX2N Tracerlab modules for the synthesis of the [¹¹C]methionine, [¹⁸F]choline and [¹⁸F]fluorodopa via nucleophilic pathway in FX2C/N module. [¹¹C]methionine was standardized in FX2C module using two different precursors, and purified using C18 cartridge based technique. [¹⁸F]methylcholine was synthesized using dimethylaminoethanol precursor and purified using cartridge-based method. [¹⁸F]fluorodopa was synthesized using nucleophilic precursor and purified using in-built preparative HPLC on FX2N module. All radioactive intermediates and chem. impurities were evaluated by anal. HPLC. The radiochem. purity of D and L-[¹¹C]methionine were 4.6 ¡À 3.2% and 95.4 ¡À 3.6% while other chem. impurities were less than prescribed limits with yield of 20 ¡À 5%. [¹⁸F]fluoromethylcholine was prepared with high radiochem. purity of 97.3 ¡À 2.6% with yield of 8 ¡À 3%. [¹⁸F]fluorodopa was synthesized with high radiochem. purity of 95.8 ¡À 1.4% with 15 ¡À 3% yield. The adaptation of [¹⁸F]fluorodopa synthesis to FX2N module via designing synthesis sequence and purified through online HPLC has provided high radiochem. purity. PET-MR imaging was done using these tracers which have validated the synthesis and their availability for future clin. applications.

Applied Radiation and Isotopes published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Formula: C17H37NO3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Vichkanova, S. A. published the artcileAntiviral activity of some 1,3,5-triazaadamantane derivatives, Computed Properties of 14707-75-6, the publication is Farmakologiya i Toksikologiya (Moscow) (1974), 37(1), 76-80, database is CAplus.

All 11 derivatives of 1,3,5-triazaadamantane (I) [281-31-2] tested inhibited the growth of Newcastle disease virus in vitro, with 7-bromo-1,3,5-triazaadamantane [51706-46-8] and 7-amino-1,3,5-triazaadamantane-HCl [51706-47-9] the most effective. 7-Nitro-1,3,5-triazaadamantane [14612-28-3] exerted antimicrobial activity against influenza A2 virus in vitro and 7-nitro-1,3,5-triazaadamantane-HCl [51706-48-0] inhibited 4 herpes virus strains in chick fibroblast cultures. None of the I derivatives were active against Aujeszky virus.

Farmakologiya i Toksikologiya (Moscow) published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C18H17NO8, Computed Properties of 14707-75-6.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Kubota, L. T. published the artcileElectrochemical study of flavins, phenazines, phenoxazines, and phenothiazines immobilized on zirconium phosphate, COA of Formula: C18H15N3O3, the publication is Electroanalysis (1999), 11(10-11), 719-728, database is CAplus.

Adsorption of a number of flavins, phenazines, phenoxazines, and phenothiazines on zirconium phosphate (ZP) was carried out in aqueous solution The adsorbed organic dyes on ZP were used to prepare modified C paste electrodes. The electrochem. properties of the immobilized dyes were investigated and also their possible use to electrocatalytically oxidize NADH. The formal potential (E⁰‘) of most of the adsorbed flavins, phenoxazines, and phenothiazines shifted markedly towards more pos. potentials compared with their values in solution The pH of the contacting solution did not affect their E⁰‘-values between pH 1-9. The phenazines did neither present good electrochem. response nor electrocatalytic activity for NADH oxidation and their E⁰‘-values remained pH dependent. In contrast, adsorbed flavins, phenoxazines, and phenothiazines presented good electron transfer rates between the electrode and the adsorbed mol. dye at pH 7.0.

Electroanalysis published new progress about 10510-54-0. 10510-54-0 belongs to catalysis-chemistry, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Inhibitor,Inhibitor, name is 5,9-Diaminobenzo[a]phenoxazin-7-ium acetate, and the molecular formula is C18H15N3O3, COA of Formula: C18H15N3O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Habyarimana, Ephrem published the artcileWhole-genome resequencing of Sorghum bicolor and S. bicolor x S. halepense lines provides new insights for improving plant agroecological characteristics, Computed Properties of 63-68-3, the publication is Scientific Reports (2022), 12(1), 5556, database is CAplus and MEDLINE.

Sorghum (Sorghum bicolor L. (Moench)) is the world’s fifth economically most important cereal and is a staple particularly in the semi-arid tropics of Africa and Asia. Genetic gains in this crop can benefit from wild relatives such as Sorghum halepense. Genome sequences including those from this wild species can boost the study of genome-wide and intraspecific variation for dissecting the genetic basis and improving important traits in sorghum. The whole-genome resequencing carried out in this work on a panel of 172 populations of S. bicolor and S. bicolor x S. halepense (SbxSh) advanced lines generated a total of 567,046,841 SNPs, 91,825,474 indels, 1,532,171 SVs, and 4,973,961 CNVs. Clearly, SbxSh accumulated more variants and mutations with powerful effects on genetic differentiation. A total of 5,548 genes private to SbxSh mapped to biol. process GO enrichment terms; 34 of these genes mapped to root system development (GO: 0022622). Two of the root specific genes i.e., ROOT PRIMORDIUM DEFECTIVE 1 (RPD1; GeneID: 8054879) and RETARDED ROOT GROWTH (RRG, GeneID: 8072111), were found to exert direct effect on root growth and development. This is the first report on whole-genome resequencing of a sorghum panel that includes S. halepense genome. Mining the private variants and genes of this wild species can provide insights capable of boosting sorghum genetic improvement, particularly the perenniality trait that is compliant with agroecol. practices, sustainable agriculture, and climate change resilience.

Scientific Reports published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Computed Properties of 63-68-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Dilman, A. D. published the artcileTrifluoromethylation and pentafluorophenylation of enamines, Recommanded Product: Trimethyl(perfluorophenyl)silane, the publication is Russian Chemical Bulletin (2007), 56(8), 1522-1525, database is CAplus.

Reaction of enamines, e.g., I, with Me₃SiCF₃ and Me₃SiC₆F₅ in the presence of carboxylic acids leading to ¦Á-CF₃– and ¦Á-C₆F₅-substituted amines, e.g., II, has been studied. 3-Cyanobenzoic acid was found to be the optimal promoter of these reactions.

Russian Chemical Bulletin published new progress about 1206-46-8. 1206-46-8 belongs to catalysis-chemistry, auxiliary class Organic Silicones, name is Trimethyl(perfluorophenyl)silane, and the molecular formula is C9H9F5Si, Recommanded Product: Trimethyl(perfluorophenyl)silane.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Gaikwad, Mahadev published the artcileSynthesis, characterization and anti-microbial screening of novel substituted thiadiazole-5-aminotetrazoles, SDS of cas: 118-90-1, the publication is Chemistry & Biology Interface (2022), 12(1), 1-6, database is CAplus.

An efficient and green synthesis of substituted thiadiazole-5-aminotetrazoles I [R = Ph, benzyl, cinnamyl, etc.] were prepared in-situ by reaction of cyanogen bromide and sodium azide to generate a cyanogen azide as an intermediate in acetonitrile. The cyclization reaction of cyanogen azide and substituted thiadiazoles containing primary amines in acetonitrile-water solvent media, gave the intermediate 1-substituted 5-aminotetrazoles in good yield. In addition, to further evaluate the role of synthesized mols. for antimicrobial activities, and it’s found that compound I [R = 4-O₂NC₆H₄, 2-IC₆H₄] showed a good antimicrobial for broad range of bacterial and fungal pathogens.

Chemistry & Biology Interface published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, SDS of cas: 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Guimond, Nicolas published the artcileRhodium(III)-Catalyzed Heterocycle Synthesis Using an Internal Oxidant: Improved Reactivity and Mechanistic Studies, Recommanded Product: O-Pivaloylhydroxylamine trifluoromethanesulfonate, the publication is Journal of the American Chemical Society (2011), 133(16), 6449-6457, database is CAplus and MEDLINE.

Directing groups that can act as internal oxidants have recently been shown to be beneficial in metal-catalyzed heterocycle syntheses that undergo C-H functionalization. Pursuant to the rhodium(III)-catalyzed redox-neutral isoquinolone synthesis that we recently reported, we present in this article the development of a more reactive internal oxidant/directing group that can promote the formation of a wide variety of isoquinolones at room temperature while employing low catalyst loadings (0.5 mol %). In contrast to previously reported oxidative rhodium(III)-catalyzed heterocycle syntheses, the new conditions allow for the first time the use of terminal alkynes. Also, it is shown that the use of alkenes, including ethylene, instead of alkynes leads to the room temperature formation of 3,4-dihydroisoquinolones. Mechanistic investigations of this new system point to a change in the turnover limiting step of the catalytic cycle relative to the previously reported conditions. Concerted metalation-deprotonation (CMD) is now proposed to be the turnover limiting step. In addition, DFT calculations conducted on this system agree with a stepwise C-N bond reductive elimination/N-O bond oxidative addition mechanism to afford the desired heterocycle. Concepts highlighted by the calculations were found to be consistent with exptl. results.

Journal of the American Chemical Society published new progress about 1293990-73-4. 1293990-73-4 belongs to catalysis-chemistry, auxiliary class Aliphatic Chain, name is O-Pivaloylhydroxylamine trifluoromethanesulfonate, and the molecular formula is C6H12F3NO5S, Recommanded Product: O-Pivaloylhydroxylamine trifluoromethanesulfonate.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia