Catalysis-chemistry

Xu, Jian published the artcileCopper-Catalyzed P-Arylation via Direct Coupling of Diaryliodonium Salts with Phosphorus Nucleophiles at Room Temperature, Quality Control of 23897-16-7, the publication is Journal of Organic Chemistry (2013), 78(16), 8176-8183, database is CAplus and MEDLINE.

A new method for copper-catalyzed P-C bond formation through reaction of phosphorus nucleophiles with diaryliodonium salts at room temperature is described. Most target products are obtained with this method in high yields within a short reaction time of 10 min. It can be easily adapted to large-scale preparations When unsym. iodonium salts are employed, nucleophilic substitution occurs preferentially on the sterically hindered aromatic ring or the more electron-deficient ring.

Journal of Organic Chemistry published new progress about 23897-16-7. 23897-16-7 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Dimesitylphosphine oxide, and the molecular formula is C10H16O2, Quality Control of 23897-16-7.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Tang, Shengbiao published the artcileIridium-catalyzed regio- and enantioselective allylic esterification of secondary allylic alcohols with carboxylic acids, Related Products of catalysis-chemistry, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(84), 11080-11083, database is CAplus and MEDLINE.

Authors report herein an iridium-catalyzed asym. allylic esterification of racemic secondary allylic alcs. using free carboxylic acids as nucleophiles under mild conditions with broad functional group tolerance, exhibiting excellent regio- and enantioselectivity.

Chemical Communications (Cambridge, United Kingdom) published new progress about 104-03-0. 104-03-0 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Carboxylic acid,Benzene, name is 4-Nitrophenylacetic acid, and the molecular formula is C16H10O5, Related Products of catalysis-chemistry.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Lu, Yuting published the artcileComparison of gut microbial communities, free amino acids or fatty acids contents in the muscle of wild Aristichthys nobilis from Xinlicheng reservoir and Chagan lake, Application of (S)-2-Amino-4-(methylthio)butanoic acid, the publication is BMC Microbiology (2022), 22(1), 32, database is CAplus and MEDLINE.

Fish is favored by consumers, while amino acids and fatty acids are the main nutrients of muscle. At present, it has been found that the gut microbial community may be involved in the regulation of host material anabolism. Juvenile and adult bighead carp (A. nobilis) from Chagan lake and Xinlicheng reservoir were selected, and divided into four groups to compare the differences of gut microbial communities, free amino acid and fatty acids in muscle. The results showed that fish in different lakes or ages contained specific microbiota, the gut microbial structure was similar, but the microbial content was significantly different. Gut microbial abundance of juvenile fish in Chagan lake was significantly higher than that of other groups. Phylum level anal. Proteobacteria was the dominant gut bacteria of fish in both adult and juvenile fish from two sep. lakes. Actinobacteria was another dominant bacterial phylum in juvenile fish in both lakes. Contents of free amino acids and fatty acids in muscle were detected, and the relationships between them and gut microbial communities were analyzed. Bighead carp grew from juvenile to adult, Actinobacteria abundance decreased (P < 0.05) and Proteobacteria increased (P < 0.05). Proteobacteria was pos. correlated with the contents of Thr, Lys, Pro, Asp, Gly and Glu, Actinobacteria was neg. correlated with Met and His. Meanwhile, EPA and DHA were pos. correlated with Proteobacteria, EPA and DHA were not significantly associated with Actinobacteria. It was speculated that the contents of free amino acids and fatty acids in muscle might be affected by the difference of gut microbiota, thus affecting the taste and nutritional quality.

BMC Microbiology published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Application of (S)-2-Amino-4-(methylthio)butanoic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Zhou, Fabin published the artcileA terphenyl phosphine as a highly efficient ligand for palladium-catalysed amination of aryl halides with 1¡ã anilines, COA of Formula: C12H9N3O4, the publication is Journal of Catalysis (2021), 238-243, database is CAplus.

A terphenyl phosphine ligand (2,6-bis(2,4,6-triisopropylphenyl)phenyl-dicyclohexylphosphine, TXPhos) and its supported palladium complex [(TXPhos)(allyl)PdCl] have been developed and the catalyst system is highly efficient in amination of aryl halides ArX (Ar = Ph, 2-methoxyphenyl, 4-cyanophenyl, etc.; X = Cl, Br, I) with 1¡ã anilines RNH₂ (R = Ph, 2-nitrophenyl, 2,5-dimethylphenyl, etc.), especially effective for densely functionalized substrates including both partners possessing ortho-ester, acetyl, nitrile and nitro groups. With the TXPhos-supported catalyst system, many partner combinations have been unprecedentedly realized and the base scope has been even extended to KOAc, which is even the best choice in the amination of 2-nitrochlorobenzene.

Journal of Catalysis published new progress about 1821-27-8. 1821-27-8 belongs to catalysis-chemistry, auxiliary class Nitro Compound,Amine,Benzene, name is Bis(4-nitrophenyl)amine, and the molecular formula is C14H10O4, COA of Formula: C12H9N3O4.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Liu, Chao published the artcileSynthesis, crystal structure and catalytic properties of novel Zn-N metal complexes based on ethylenediamine derivatives, Safety of N1,N2-Dibenzylethane-1,2-diamine, the publication is Rengong Jingti Xuebao (2015), 44(1), 287-293, database is CAplus.

Two novel Zn-N metal complexes [Zn(OAc)₂L] (L = N,N-dimethylethylenediamine (1), N,N’-dibenzylethylenediamine (2)) were synthesized with N,N-dimethylethylenediamine and N,N’-dibenzylethylenediamine as ligand, and the structures were characterized and analyzed by ¹H NMR, IR, elemental anal. and x-ray single crystal diffraction. The catalytic properties of the complexes in Henry reaction of aromatic aldehydes with nitromethane and the influences of the reaction conditions were studied, and the applicable scope of aromatic aldehydes in Henry reaction with complex as catalyst is discussed. The complexes can efficiently catalyze the Henry reaction of different aromatic aldehydes with nitromethane under the conditions as follows: methanol as solvent, complex 1 as catalyst mediated by equimolar triethylamine, and catalyst amount for 25 mol%.

Rengong Jingti Xuebao published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C16H20N2, Safety of N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Meizi published the artcileExploring the N-terminus region: Synthesis, bioactivity and 3D-QSAR of allatostatin analogs as novel insect growth regulators, Safety of N1,N2-Dibenzylethane-1,2-diamine, the publication is Chinese Chemical Letters (2018), 29(9), 1375-1378, database is CAplus.

Allatostatins (ASTs), a family of insect neuropeptide, can inhibit juvenile hormone (JH) biosynthesis by the corpora allata (CA) in Diploptera punctata, and therefore be regarded as potential leads for the discovery of new insect growth regulators (IGRs). But several shortcomings, such as their sensitivity to peptidases and high cost, impeded their practical application in pest management. In order to discover new IGRs, one AST analog B1 (I) possessing non-peptide group was discovered with high ability to inhibit JH biosynthesis in vitro (IC₅₀: 0.09 ¦Ìmol/L) in our previous studies. In the present work, two series of I analogs with different substituents on the N-terminus region were designed and synthesized. The result suggested that benzene showed better activity than other heterocycles, and the para-substitution on the benzene was beneficial for activity. Moreover, analogs with logP value over 2.0 exhibited good activity, which indicated the hydrophobicity is important to the bioactivity. Three dimension quant. structure-activity relationship (3D-QSAR) studies were performed to highlight the structural requirements of AST analogs, which demonstrated introduction of bulkier substituents on the N-terminus would increase the activity. Analog (II) (IC₅₀: 0.08 ¦Ìmol/L) exhibited similar inhibitory activity to the lead B1, but its synthetic route was simpler than B1. Therefore, II could be used as a new lead compound for the discovery ecofriendly IGRs.

Chinese Chemical Letters published new progress about 140-28-3. 140-28-3 belongs to catalysis-chemistry, auxiliary class Benzenes, name is N1,N2-Dibenzylethane-1,2-diamine, and the molecular formula is C2H4ClNO, Safety of N1,N2-Dibenzylethane-1,2-diamine.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Huang, Y. published the artcileHydrothermal synthesis, structure, and properties of a novel 2D stair-like zinc coordination polymer with benzene-1,2-dioxyacetate, Name: 2,2-(1,2-Phenylenebis(oxy))diacetic acid, the publication is Russian Journal of Coordination Chemistry (2010), 36(6), 452-457, database is CAplus.

The hydrothermal reaction of Zn(CH₃COOH)₂¡¤6H₂O with benzene-1,2-di(oxyacetic acid) (H₂BDOA) and 1,4-bis(imidazol-1-yl)butane (Bimb) yields a novel 2D zinc coordination polymer, [Zn(BDOA)(Bimb)]¡¤3H₂O_n, in which the Bimb ligands link the 1D Zn-BDOA chains into two kinds of 1D ladder-like structure to construct a 2D stair-like structure. It exhibits intense blue photoluminescence upon photoexcitation.

Russian Journal of Coordination Chemistry published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Name: 2,2-(1,2-Phenylenebis(oxy))diacetic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Wang, Guan published the artcileDecorating an individual living cell with a shell of controllable thickness by cytocompatible surface initiated graft polymerization, Quality Control of 5411-14-3, the publication is Chemical Communications (Cambridge, United Kingdom) (2018), 54(37), 4677-4680, database is CAplus and MEDLINE.

Surface engineering of individual living cells is a promising field for cell-based applications. However, engineering individual cells with controllable thickness by chem. methods has been rarely studied. This article describes the development of a new cytocompatible chem. strategy to decorate individual living cells. The thicknesses of the crosslinked shells could be conveniently controlled by the irradiation time, visible light intensity, or monomer concentration Moreover, the lag phase of the yeast cell division was extended and their stability against lysis was improved, which could also be tuned by controlling the shell thickness.

Chemical Communications (Cambridge, United Kingdom) published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C16H12O, Quality Control of 5411-14-3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Jiang, Yongwei published the artcileSynthesis, in vitro evaluation and molecular docking studies of new triazole derivatives as antifungal agents, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, the publication is Bioorganic & Medicinal Chemistry Letters (2011), 21(15), 4471-4475, database is CAplus and MEDLINE.

On the basis of the active site of lanosterol 14¦Á-demethylase from Candida albicans (CACYP51), a series of 1-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)-1H-1,2,4-triazol-5(4H)-one derivatives I (R = 4-F, 2-F, 4-Cl, 3-Cl, 2,4-Cl₂, 3-Br, 2-Br, 4-MeO, 3-MeO, 4-OCF₃, 4-Me, 3-Me, 2-Me, 3,4-Me₂, 2,4-Me₂, 4-nPr, 4-Bu, 4-pentyl, 4-hexyl, 4-tBu, 4-iPr) and II (R = 4-F, 3-F, 2-F, 4-Cl, 3,4-Cl₂, 4-Br, 3-Br, 4-Me, 2,3-Me₂, 4-MeO, 3,4-(MeO)₂,2,4-(MeO)₂, 4-NO₂, 3-NO₂, 2-NO₂, 3-CN) were synthesized as fluconazole analogs. Results of the preliminary antifungal tests against eight human pathogenic fungi in vitro showed that these compounds exhibited activities to some extent, and some displayed excellent antifungal activities against C. albicans than reference drug fluconazole. Flexible mol. docking was used to analyze the structure-activity relationships (SARs) of the target compounds The designed compounds interact with CACYP51 through hydrophobic, van der Waals and hydrogen-bonding interactions.

Bioorganic & Medicinal Chemistry Letters published new progress about 16909-09-4. 16909-09-4 belongs to catalysis-chemistry, auxiliary class Alkenyl,Carboxylic acid,Benzene,Ether, name is (E)-3-(2,4-Dimethoxyphenyl)acrylic acid, and the molecular formula is C11H12O4, Recommanded Product: (E)-3-(2,4-Dimethoxyphenyl)acrylic acid.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia

Huang, Yuanjing published the artcilePotassium tert-Butoxide Facilitated Amination of Carboxylic Acids with N,N-Dimethylformamide, SDS of cas: 118-90-1, the publication is Synthesis (2022), 54(16), 3595-3604, database is CAplus.

A practical and efficient potassium tert-butoxide (KO^tBu)-facilitated amination of carboxylic acids with N,N-dimethylamine was described. In the presence of catalytic amount of KO^tBu, a variety of aliphatic and aromatic carboxylic acids were transformed to N,N-dimethylamides using DMF as the dimethylamine reagent with the assistance of trimethylacetic anhydride. The applicability of this protocol was demonstrated by late-stage dimethylamidation of complex drug mols. A plausible reaction mechanism involving KO^tBu-facilitated in-situ amine generation from formamide decomposition and anhydride-mediated condensation was proposed on the basis of mechanistic investigations.

Synthesis published new progress about 118-90-1. 118-90-1 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Natural product, name is 2-Methylbenzoic acid, and the molecular formula is C8H8O2, SDS of cas: 118-90-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia