Harders, H.’s team published research in Arzneimittel-Forschung in 30 | CAS: 38260-01-4

Arzneimittel-Forschung published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C6H20Cl2N4, Safety of N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride.

Harders, H. published the artcileUrinary copper excretion from rats following administration of aliphatic and alicyclic polyamines, Safety of N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, the publication is Arzneimittel-Forschung (1980), 30(2), 254-8, database is CAplus and MEDLINE.

The effect of oral aliphatic and alicyclic tetramines and tetramine analogs (with 2 N-atoms substituted by O) on Cu excretion was compared with that of D-penicillamine in rats. TETA-HCl (3,6-diazaoctan-1,8-diamine-2HCl) [38260-01-4] and BE 6184-HCl (3,7-diazanonan-1,9-diamine-3HCl) [73510-17-5] were the most active substances. However, simultaneous administration of TETA and D-penicillamine did not potentiate the cupriuretic effect. TETA, s.c. administered, was 3-fold more effective than the orally administered drug.

Arzneimittel-Forschung published new progress about 38260-01-4. 38260-01-4 belongs to catalysis-chemistry, auxiliary class Chelating Agents, name is N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride, and the molecular formula is C6H20Cl2N4, Safety of N1,N1′-(Ethane-1,2-diyl)bis(ethane-1,2-diamine) dihydrochloride.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia