Kay, John E.’s team published research in FEBS Letters in 121 | CAS: 10517-44-9

FEBS Letters published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, SDS of cas: 10517-44-9.

Kay, John E. published the artcileDirect effects of 1,3-diaminopropane on reticulocyte lysate protein synthesis, SDS of cas: 10517-44-9, the publication is FEBS Letters (1980), 121(2), 309-12, database is CAplus and MEDLINE.

1,3-Diaminopropane-2HCl (I) [10517-44-9] inhibited protein synthesis by reticulocyte lysates in the presence of 2 mM Mg2+. This was apparently a simple cation effect, since I itself supported protein synthesis by the system in the absence of normal divalent cations. The inhibitory action of I was not due to an antagonistic effect toward spermidine, a natural polyamine associated with protein synthesis, because the inhibition was not diminished when the lyzate was supplemented with large amounts of spermidine-HCl [334-50-9]. Direct inhibition of protein synthesis by I would include, among other effects, a reduction in the concentration of enzymes required for polyamine synthesis. This raises questions as to the specificity of I as an inhibitor of polyamine formation.

FEBS Letters published new progress about 10517-44-9. 10517-44-9 belongs to catalysis-chemistry, auxiliary class Salt,Amine,Aliphatic hydrocarbon chain, name is Propane-1,3-diamine dihydrochloride, and the molecular formula is C3H12Cl2N2, SDS of cas: 10517-44-9.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia