Krishnamurti, Vinayak published the artcileAqueous Base Promoted O-Difluoromethylation of Carboxylic Acids with TMSCF2Br: Bench-Top Access to Difluoromethyl Esters, Quality Control of 119-80-2, the publication is Organic Letters (2019), 21(23), 9377-9380, database is CAplus and MEDLINE.
A method for the O-difluoromethylation of carboxylic acids using com. available TMSCF2Br is disclosed. The devised bench-top reaction system is air-stable and offers mild reaction conditions while using readily available reagents and solvents. The method is applicable to both aliphatic and aromatic carboxylic acids while demonstrating compatibility with a range of commonly encountered functional groups. The difluoromethyl esters of FDA approved drugs and pharmaceutically relevant mols. are also presented, demonstrating the potential for late-stage functionalization.
Organic Letters published new progress about 119-80-2. 119-80-2 belongs to catalysis-chemistry, auxiliary class sulfides,Carboxylic acid,Benzene, name is 2,2′-Dithiodibenzoic acid, and the molecular formula is C14H10O4S2, Quality Control of 119-80-2.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia