Narayan, Rishikesh published the artcileCatalytic enantioselective synthesis of functionalized tropanes reveals novel inhibitors of hedgehog signaling, Quality Control of 4230-93-7, the publication is Angewandte Chemie, International Edition (2013), 52(49), 12892-12896, database is CAplus and MEDLINE.
We have developed a very efficient Cu(I)- catalyzed highly diastereoselective and enantioselective [3+2] cycloaddition reaction of 1,3-fused cyclic azomethine ylides and nitroalkenes. For the first time, S-shaped azomethine ylides were successfully used in an enantioselective catalytic process. This novel method provides an unprecedented and general access to functionalized tropane scaffolds that embody quaternary and tertiary stereocenters in a stereoselective manner. It allows the generation of stereochem. complex products in a single step under mild reaction conditions, and is characterized by a broad scope and versatility. Furthermore, the investigation of a tropane-inspired compound collection in a process that monitored signaling through the hedgehog pathway revealed a novel class of hedgehog-signaling inhibitors.
Angewandte Chemie, International Edition published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Quality Control of 4230-93-7.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia