Rakowitz, Dietmar’s team published research in Archiv der Pharmazie (Weinheim, Germany) in 339 | CAS: 1860-58-8

Archiv der Pharmazie (Weinheim, Germany) published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, Quality Control of 1860-58-8.

Rakowitz, Dietmar published the artcileSynthesis and aldose reductase inhibitory activities of novel O-substituted hydroxyphenylacetic acid derivatives, Quality Control of 1860-58-8, the publication is Archiv der Pharmazie (Weinheim, Germany) (2006), 339(10), 547-558, database is CAplus and MEDLINE.

In continuation of our work aimed towards the preparation of novel aldose reductase inhibitors, several O-substituted hydroxyphenylacetic acid derivatives were investigated. The highest inhibitory activity was found for compounds 7b (3-(cyclohexylmethoxy)benzeneacetic acid) and 7c (4-(cyclohexylmethoxy)benzeneacetic acid). This result demonstrates that within these series, this moiety is a useful surrogate for the 4-bromo-2-fluorobenzyl residue which can be often found in potent aldose reductase inhibitors.

Archiv der Pharmazie (Weinheim, Germany) published new progress about 1860-58-8. 1860-58-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2-(3-(Benzyloxy)phenyl)acetic acid, and the molecular formula is C15H14O3, Quality Control of 1860-58-8.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia