RGD-porphyrin conjugates: Synthesis and potential application in photodynamic therapy was written by Chaleix, Vincent;Sol, Vincent;Huang, Yi-Ming;Guilloton, Michel;Granet, Robert;Blais, Jean Claude;Krausz, Pierre. And the article was included in European Journal of Organic Chemistry in 2003.Quality Control of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol The following contents are mentioned in the article:
We report a convenient solid-phase synthesis and characterization of a new class of glycosylated porphyrins bearing the RGD tripeptide, designed for photodynamic cancer therapy. The photocytotoxicities of these compounds against the K562 leukemia cell line are also presented and compared to the effect of Photofrin II. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Quality Control of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol).
4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Ligand, in chemistry, any atom or molecule attached to a central atom, usually a metallic element, in a coordination or complex compound. It is clear that future advancements in metal complexes and their applications crucially depend on ligand design, whereas the ligand electronic, steric and topological properties provide numerous improvements to the reactivity and selectivity at the metal centers.Quality Control of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI