Ultrasensitive gas phase detection of 2,4,6-trinitrotoluene by non-covalently functionalized graphene field effect transistors was written by Gajarushi, Ashwini S.;Surya, Sandeep G.;Walawalkar, Mrinalini G.;Ravikanth, M.;Rao, V. Ramgopal;Subramaniam, Chandramouli. And the article was included in Analyst (Cambridge, United Kingdom) in 2020.Safety of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol The following contents are mentioned in the article:
The high energy d. (4.2 MJ kg-1) and low vapor pressure (7.2 ¡Á 10-9 atm) of chem. explosives such as TNT (2,4,6-trinitrotoluene) pose a grave security risk demanding immediate attention. Detection of such hazardous and highly challenging chems. demands specific, ultra-sensitive and rapid detection platforms that can concomitantly transduce the signal as an elec. readout. Although chemo-sensitive strategies have been investigated, the majority of them are restricted to detecting TNT from solutions and are therefore not implementable in real-time, on-field situations. Addressing this demand, we report an ultra-sensitive (parts-per-billion) and rapid (?40 s) detection platform for TNT based on non-covalently functionalized graphene field effect transistors (GFETs). This multi-parametric GFET detector exhibits a reliable and specific modulation in its Dirac point upon exposure to TNT in the vapor phase. The chem. specificity provided by 5-(4-hydroxyphenyl)-10,15,20-tri(p-tolyl) zinc porphyrin (ZnTTPOH) is synergistically combined with the high surface sensitivity of graphene through a non-covalent functionalization approach to realize p-doped GFETs (Zn-GFETs). Such a FET platform exhibits extremely sensitive shifts in Dirac point (¦¤DP) that correlate with the number of nitro groups present in the analyte. Analytes with mono-, di-, and tri-nitro substituted aromatic mols. exhibit distinctly different ¦¤DP, leading to unprecedented specificity towards TNT. Addnl., the Dirac point of Zn-GFETs is invariant for common and potential interferons such as acetone and 2-propanol (perfume emulsifiers) thereby validating their practical applicability. Furthermore, the ¦¤DP is also manifested as changes in the contact potential of GFETs, indicating that sub-monolayer coverage of ZnTTPOH is sufficient to modulate the transfer characteristics of GFETs over an area 1000 times larger than the dopant dimensions. Specifically, ZnTTPOH-functionalized GFETs exhibit p-doped behavior with pos. ¦¤DP with respect to pristine GFETs. Such p-doped Zn-GFETs undergo selective charge-transfer mediated interactions with TNT resulting in enhanced electron withdrawal from Zn-GFETs. Thus the ¦¤DP shifts to a higher pos. gate voltage leading to the dichotomous combination of the highest signal generation (1.2 ¡Á 1012 V mol-1) with ppb level mol. sensitivity. Significantly, the signal generated due to TNT is 105 times higher in magnitude compared to other potential interferons. The signal reliability is established in cross-sensitivity measurements carried out with a TNT-mDNB (1:10 molar ratio) mixture pointing to high specificity for immediate applications under atmospherically relevant conditions pertaining to homeland security and global safety. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Safety of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol).
4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Catalytic transformations have become a mainstay in the toolkit of the synthetic and increasing non-synthetic chemist alike. And they often provide a convenient approach to fine-tuning the performance of known catalysts.Safety of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI