Synthesis and structural analysis of novel glycosylated meso-arylporphyrins for application to cancer phototherapy was written by Gaud, Olivier;Granet, Robert;Kaouadji, Mourad;Krausz, Pierre;Blais, Jean Claude;Bolbach, Gerard. And the article was included in Canadian Journal of Chemistry in 1996.SDS of cas: 57412-08-5 The following contents are mentioned in the article:
The synthesis of 13 novel meso-glycosylarylporphyrins where the carbohydrate moiety is separated from the aryl substituent by a spacer arm is described. These compounds were synthesized by different methods, either by direct glycosylation of the ortho- or para-hydroxyalkoxyarylporphyrin or by condensation of glycosylated aldehyde with pyrrole or meso-(p-tolyl)dipyrromethane. In all cases, a ¦Â configuration was observed Deprotection of the sugar then followed in a basic medium. A detailed 1H and 13C NMR study allowed complete structural determination The UV-visible and laser desorption mass spectra are presented. Due to their sensitizing abilities, these resultant compounds are of considerable interest for photodynamic therapy. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5SDS of cas: 57412-08-5).
4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. The atoms and molecules used as ligands are almost always those that are capable of functioning as the electron-pair donor in the electron-pair bond (a coordinate covalent bond) formed with the metal atom. The ability of ligands to engender a variety of useful properties of organometallic complexes is the major enabling force for the discovery of new catalytic reactions, activation of small molecules, dramatically enhanced reactivity.SDS of cas: 57412-08-5
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI