The synthesis of new potential photosensitizers. Part 3. Tetraphenylporphyrin esters of profens was written by Kus, Piotr;Kozik, Violetta;Rojkiewicz, Marcin;Sochanik, Aleksander;Szurko, Agnieszka;Kempa, Marta;Kozub, Patrycja;Rams-Baron, Marzena;Jarzembek, Krystyna;Stefaniak, Marta;Sakowicz, Julian. And the article was included in Dyes and Pigments in 2015.Product Details of 57412-08-5 The following contents are mentioned in the article:
Six tetra-Ph derivatives of arylpropionic acids (profens) were synthesized in search for improved novel photosensitizers that might find application in photodynamic therapy (PDT) of various cancers. Our goal was to alter hydrophobic-hydrophylic characteristics of the tetraphenylporphyrin ring by substitution with propionyl derivatives As starting materials we used profens known primarily from their widespread use as non-steroidal anti-inflammatory drugs (ibuprofen, naproxen, ketoprofen, fenoprofen, fluorbiprofen) and 2-phenylpropionic acid (model compound). The new compounds were characterized using spectroscopic and photophys. methods with focus given to measurement of mols.’ lifetime in excited triplet state, time-resolved singlet oxygen phosphorescence and measurement of photostability. Fluorescence quantum yields were also determined; data revealed no planarity changes in the porphyrin mol. following substitution with profens. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Product Details of 57412-08-5).
4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Ligands, especially phosphines and carbenes, can play a key role in modifying and controlling homogeneous organometallic catalysts. And they often provide a convenient approach to fine-tuning the performance of known catalysts.Product Details of 57412-08-5
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI