Conformations of cytochrome P-450 models by 1D and 2D NMR was written by Ning, Yongcheng;Yuan, Lihua;Wang, Fengyan;Yuan, Haodan;Chen, Shuhua;Zhao, Huaming;Feng, Yuping;Mao, Yingqun. And the article was included in Tsinghua Science and Technology in 1996.Name: 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol The following contents are mentioned in the article:
Conformations of organic compounds in solution relate to their phys. and chem. properties and biol. activities. Two calix[4]arene-porphyrin derivatives were synthesized as models of cytochrome P 450 monooxygenase. The conformations of the models were determined using DQFCOSY (double quantum filter correlation spectroscopy), NOESY (nuclear overhauser effect spectroscopy), etc. The calix[4]arene part showed cone conformation in one compound and showed mainly partial cone conformation in the other compound The calix[4]arene and the porphyrin were situated side by side in the first compound, and above and below each other in the second compound This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Name: 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol).
4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. Ligands, especially phosphines and carbenes, can play a key role in modifying and controlling homogeneous organometallic catalysts. The ability of ligands to engender a variety of useful properties of organometallic complexes is the major enabling force for the discovery of new catalytic reactions, activation of small molecules, dramatically enhanced reactivity.Name: 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI