Synthesis and biological evaluation of thio-glycosylated meso-aryl-porphyrins was written by Sylvain, Isabelle;Benhaddou, Rachida;Carre, Vincent;Cottaz, Sylvain;Driguez, Hugues;Granet, Robert;Guilloton, Michel;Krausz, Pierre. And the article was included in Journal of Porphyrins and Phthalocyanines in 1999.Quality Control of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol The following contents are mentioned in the article:
A new class of porphyrins bearing thio-glycosyl groups is presented in order to improve targeting of malignant cells and resistance to glycosidases. These compounds were synthesized in four steps. They produced 1O2 and their photo-cytotoxicity against the yeast Saccharomyces cerevisiae was compared with the effect of hematoporphyrin. This study involved multiple reactions and reactants, such as 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5Quality Control of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol).
4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol (cas: 57412-08-5) belongs to catalyst ligands. The atoms and molecules used as ligands are almost always those that are capable of functioning as the electron-pair donor in the electron-pair bond (a coordinate covalent bond) formed with the metal atom. Replacing precious metals with cheaper and more environmentally friendly metals is regarded as a highly desirable goal in the field of catalysis.Quality Control of 4-(10,15,20-Tri-p-tolylporphyrin-5-yl)phenol
Referemce:
Metal catalyst and ligand design,
Ligand Template Strategies for Catalyst Encapsulation – NCBI