Armstrong, Susan K. published the artcileA new method for stereoselective homoallylic amine synthesis, Recommanded Product: Allyldiphenylphosphine oxide, the publication is Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1993), 1433-47, database is CAplus.
Nitrile oxide cycloadditions to readily available allylic diphenylphosphine oxides [Ph2P(O)CHR1CH:CH2; R1 = H, Me, Et, Pr, isobutyl] proceeded regioselectively and stereoselectively to give 5-(1′-diphenylphosphinoyalkyl)isoxazolines [I and II; R1 as above, R2 = Et, Pr, hexyl, Ph, Me, CO2Et,(CH2)nCO2Me, n = 2,3]. These heterocycles were reduced to ¦Ä-amino-¦Â-hydroxyalkyldiphenylphosphine oxides (III and IV; R1, R2 as above) using a combination of sodium borohydride and nickel(II) chloride. Stereospecific elimination of diphenylphosphinic acid from the reduction products using sodium hydride in N,N-dimethylformamide gave homoallylic primary amines (V and VI; R1, R2 as above) of defined stereochem.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Recommanded Product: Allyldiphenylphosphine oxide.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia