Gail, R.’s team published research in Applied Radiation and Isotopes in 45 | CAS: 17351-62-1

Applied Radiation and Isotopes published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Synthetic Route of 17351-62-1.

Gail, R. published the artcileA one step preparation of the n.c.a. fluorine-18 labeled synthons: 4-fluorobromobenzene and 4-fluoroiodobenzene, Synthetic Route of 17351-62-1, the publication is Applied Radiation and Isotopes (1994), 45(1), 105-11, database is CAplus.

4-18FC6H4X (X = Br, iodo) are interesting precursors for organometallic nucleophilic reagents. A 1-step preparation of these synthons was achieved by no-carrier-added (n.c.a.) nucleophilic exchange on the corresponding 4-bromo- and 4-iodophenyltrimethylammonium salts. The leaving ability of the trimethylammonium group increases strongly with decreasing basicity of the counteranion in the sequence: tosylate < Me sulfate < iodide < perchlorate (no data) < triflate. Systematic optimization leads to radiochem. yields of 50 ¡À 5% and 80 ¡À 5% within 5 min for the bromo and iodo derivs, resp., in AcNMe2 as the solvent.

Applied Radiation and Isotopes published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, Synthetic Route of 17351-62-1.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia