Gonzalez-Nogal, Ana M. published the artcileEpoxysilanes as substrates in regio- and stereo-specific synthesis of silylated ¦Ã-hydroxyphosphane oxides, precursors of stereodefined allylphosphane oxides, Product Details of C15H15OP, the publication is Tetrahedron (2013), 69(37), 8080-8087, database is CAplus.
Epoxysilanes experienced trans stereospecific ¦Á- or ¦Â-cleavage by the Li derivative of methyldiphenylphosphine oxide leading to different compounds The behavior of the epoxysilanes towards this nucleophilic reagent depends on the nature of the silyl group, the position of the substituents and the configuration of the epoxysilane. Unsubstituted and cis ¦Â-substituted dimethylphenylsilylepoxides underwent ¦Á-nucleophilic attack of Li methyldiphenylphosphine oxide giving stereodefined ¦Ã-phosphino-¦Â-silylalcs. Nevertheless, in the same conditions the intermediate ¦Â-hydroxysilane, formed by ¦Á-opening from trans ¦Â-substituted dimethylphenylsilylepoxides, experienced Peterson elimination to give stereodefined allylphosphine oxides. The steric requirements for the nucleophilic attack determined the regiochem. of the reaction. ¦Á-Substituted phenyldimethylsilyl- and tert-butyldiphenylsilylepoxides were exclusively attacked at the ¦Â-position affording ¦Ã-hydroxy-¦Ã-silylphosphine oxides and ¦Ã-phosphino silyl ether, resulting from Brook rearrangement. However, the allylphosphine oxides resulting from syn- or anti-elimination of ¦Â-dimethylphenylsilyl-¦Ã-hydroxyphosphine oxides, are of interest in the synthesis of phosphorylated and functionalized building blocks.
Tetrahedron published new progress about 4141-48-4. 4141-48-4 belongs to catalysis-chemistry, auxiliary class Aryl phosphine ligand,Mono-phosphine Ligands, name is Allyldiphenylphosphine oxide, and the molecular formula is C15H15OP, Product Details of C15H15OP.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia