Kwak, Min-Jin published the artcileSophorolipid protects against early-weaning syndrome by improving the gut microenvironment in early-weaned piglets, Application of (S)-2-Amino-4-(methylthio)butanoic acid, the publication is BMC Veterinary Research (2022), 18(1), 8, database is CAplus and MEDLINE.
In animals, weaning stress is the first and most critical stress. Weaning can neg. affect the growth performance of animals phys., psychol., and pathol. Our previous studies on the HT-29 cell line and early-weaned rats demonstrated that adequate sophorolipid (SPL) supplementation in feed could enhance the mucin-producing and wound healing capacities of the gut defense system by modulating gut microbiota. We conducted an experiment with one hundred forty 21-day-old early weaned piglets (L x Y x D). They were allocated into 4 treatment and 7 replications (4 pigs per pen) according to their initial body weight Body weight and feed intake were measured biweekly during exptl. period. After 6 wk, 28 pigs were randomly selected and sacrificed to collect plasma, jejunum, and cecal content samples. Dietary SPL supplementation at 5 and 10 mg/kg quadratically increased the average daily gain during the exptl. period in the treatment groups when compared with the control group. The albumin levels of piglets fed with the SPL supplemented diet were downregulated to the normal range. Moreover, in feed, SPL supplementation at 5 and 10 mg/kg improved jejunal histol. indexes and gene expression levels related to mucin secretion and local inflammation markers. Consistent with these results, adequate SPL supplementation (5 and 10 mg/kg) increased the population of Prevotella, a beneficial bacterium, and its short-chain fatty acid production in the ceca of piglets. The occurrence of diarrhea after weaning in piglets could be reduced by feeding a 10 ppm of SPL supplemented diet which improves the gut defense system by improving the microbial population and enhancing mucin layer integrity.
BMC Veterinary Research published new progress about 63-68-3. 63-68-3 belongs to catalysis-chemistry, auxiliary class Natural product, name is (S)-2-Amino-4-(methylthio)butanoic acid, and the molecular formula is C5H11NO2S, Application of (S)-2-Amino-4-(methylthio)butanoic acid.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia