Liao, Yu-Hua published the artcileOrganocatalytic asymmetric Michael addition of pyrazolin-5-ones to nitroolefins with bifunctional thiourea: stereocontrolled construction of contiguous quaternary and tertiary stereocenters, Related Products of catalysis-chemistry, the publication is Advanced Synthesis & Catalysis (2010), 352(5), 827-832, database is CAplus.
The first organocatalytic diastereo- and enantioselective Michael addition reaction of 4-substituted-pyrazolin-5-ones to nitroolefins was developed with a chiral bifunctional thiourea as organocatalyst. A wide variety of desired multi-substituted pyrazolin-5-one derivatives, e.g., I, with contiguous quaternary and tertiary stereocenters were smoothly obtained in good yields (up to 98%) with excellent enantioselectivities (up to >99% ee) and acceptable diastereoselectivities (up to 80:20). This exptl. simple process facilitated the access to various enantioenriched, multiply substituted pyrazolin-5-one derivatives, potential biol. active mols., starting from readily available starting materials.
Advanced Synthesis & Catalysis published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C10H11NO4, Related Products of catalysis-chemistry.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia