Lin, Huajian published the artcileEnhanced anti-microbial effect through cationization of a mono-triazatricyclodecane substituted asymmetric phthalocyanine, Application of 1,3,5-Triazaadamantan-7-amine, the publication is Journal of Inorganic Biochemistry (2018), 192-198, database is CAplus and MEDLINE.
Antimicrobial photodynamic therapy (aPDT) is an effective way to combat infectious diseases and antibiotic resistance. Photosensitizer is a key factor of aPDT and has triggered extensive research interest. In this study, a new asym. Zn(II) phthalocyanine mono-substituted with a triazatricyclodecane moiety (compound 3) and its cationic N-methylated derivative (compound 4) were synthesized. Their photodynamic antimicrobial activities were evaluated using bioluminescent bacterial strains. Compound 3 showed phototoxicity only toward the Gram-pos. bacteria, whereas the cationic derivative compound 4 exhibited strong anti-bacterial activity against both Gram-pos. and Gram-neg. strains. These bacterial species were eradicated (>4.0 logs or 99.99% killing) at appropriate concentrations of compound 4 with 12.7 J/cm2 of red light, demonstrating compound 4 as a potent aPDT agent.
Journal of Inorganic Biochemistry published new progress about 14707-75-6. 14707-75-6 belongs to catalysis-chemistry, auxiliary class Triazinanes, name is 1,3,5-Triazaadamantan-7-amine, and the molecular formula is C7H14N4, Application of 1,3,5-Triazaadamantan-7-amine.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia