Molander, Gary A. published the artcileSynthesis and Application of Chiral Cyclopropane-Based Ligands in Palladium-Catalyzed Allylic Alkylation, Safety of 2,4,6-Triisopropylbenzenethiol, the publication is Journal of Organic Chemistry (2004), 69(23), 8062-8069, database is CAplus and MEDLINE.
A series of chiral, cyclopropane-based phosphorus/sulfur ligands have been synthesized and evaluated in the palladium-catalyzed allylic alkylation of 1,3-diphenylpropenyl acetate with di-Me malonate. Variation of the ligand substituents at phosphorus, sulfur, and the carbon backbone revealed [2-[(1R)-1-(methylthio)ethyl]cyclopropyl]diphenylphosphine (I) to have the optimal configuration for this reaction, giving the product in high yield and with good enantioselectivity (93%). A model for the observed enantioselectivity is discussed within the context of existing models, using X-ray crystallog. data, solution-phase NMR studies, and the absolute stereochem. of the products. Selected ligands were also evaluated in the palladium-catalyzed intermol. Heck reaction and the rhodium-catalyzed hydrogenation of a dehydroamino acid.
Journal of Organic Chemistry published new progress about 22693-41-0. 22693-41-0 belongs to catalysis-chemistry, auxiliary class Other Functionalization Reagent, name is 2,4,6-Triisopropylbenzenethiol, and the molecular formula is C15H24S, Safety of 2,4,6-Triisopropylbenzenethiol.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia