Ng, Shan Shan published the artcilePalladium-Catalyzed Chemoselective Borylation of (Poly)halogenated Aryl Triflates and Their Application in Consecutive Reactions, Safety of 4-(2-(Di(adamantan-1-yl)phosphino)phenyl)morpholine, the publication is Advanced Synthesis & Catalysis (2022), 364(9), 1596-1601, database is CAplus.
Chemoselective palladium-phosphine-catalyzed borylation of halogenated aryl triflates TfOC6HnY4-nX (X = Cl, Br; Y = H, OMe, F, Me, PhCH2, aryl, CN) gave boryl triflates TfOC6HnY4-nBpin, which can be applied for Suzuki coupling with aryl chlorides in one-pot two-step procedure, giving functionalized biaryls. This study reports the palladium-catalyzed chemoselective borylation of (poly)halogenated aryl triflates with a reactivity order of C-Cl>C-OTf. A catalyst system comprising Pd(OAc)2 and SelectPhos (L1) enables a reaction with high reactivity and chemoselectivity. The consecutively chemoselective borylation reaction followed by the chemoselective intermol. Suzuki-Miyaura reaction can be performed using a one-pot two-step approach to synthesize unsym. biaryl compounds containing the triflate moiety. The reaction can be scaled up to the gram scale without diminishing the yield and chemoselectivity.
Advanced Synthesis & Catalysis published new progress about 1237588-12-3. 1237588-12-3 belongs to catalysis-chemistry, auxiliary class Mono-phosphine Ligands, name is 4-(2-(Di(adamantan-1-yl)phosphino)phenyl)morpholine, and the molecular formula is C30H42NOP, Safety of 4-(2-(Di(adamantan-1-yl)phosphino)phenyl)morpholine.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia