Smajlagic, Ivor published the artcileCharge-enhanced thiourea catalysts as hydrogen bond donors for Friedel-Crafts Alkylations, Synthetic Route of 4230-93-7, the publication is Tetrahedron (2019), 75(51), 130757, database is CAplus.
Charge-enhanced catalysis has emerged as a powerful alternative to the mainstream use of neutral catalysis. With this in mind, we report a catalytic Friedel-Crafts alkylation method catalyzed by a charged thiourea incorporating a cationic cyclopropenium moiety. Mechanistic studies, including d. functional theory computational calculations, variable time normalization anal., and 1H NMR binding studies, collectively reveal this charge-enhanced reactivity proceeds by a dual hydrogen bond-mediated LUMO-lowering mode of substrate activation. Key to these findings is the observed steady-state concentration of the catalyst with in situ derived monomeric catalytic species predominating under the reaction conditions.
Tetrahedron published new progress about 4230-93-7. 4230-93-7 belongs to catalysis-chemistry, auxiliary class Alkenyl,Nitro Compound,Benzene,Ether, name is 1,2-Dimethoxy-4-(2-nitrovinyl)benzene, and the molecular formula is C17H27BN2O4S, Synthetic Route of 4230-93-7.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia