Tosa, Monica Ioana's team published research in ChemCatChem in 5

Tosa, Monica Ioana published the artcileThe Interaction of Nitrophenylalanines with Wild Type and Mutant 4-Methylideneimidazole-5-one-less Phenylalanine Ammonia Lyase, Computed Properties of 1772-76-5, the publication is ChemCatChem (2013), 5(3), 779-783, database is CAplus.

Racemic nitrophenylalanines and (E)-nitrophenylacrylates are synthesized from the corresponding aldehydes. Both products are important for the examination of the mechanism of action of phenylalanine ammonia lyase (PAL). For the reaction of the rac-nitrophenylalanines with both wild type (wt) PAL and an 4-methylideneimidazole-5-one (MIO)-less mutant, the kinetic constants K_m and V_max are determined and compared with those of the natural substrate L-phenylalanine: the K_m values for the racemic nitrophenylalanines with wt PAL are up to 9 times higher, however, the V_max values are up to 5 times lower. Compared to wt PAL, the catalytic activity of MIO-less PAL mutant for the deamination of L-phenylalanine is approx. 400 times, while that for 3-nitrophenylalanine is approx. 50 times lower. Both wt and MIO-less PALs are enantioselective for L-nitrophenylalanines. Thus, enantiopure D-nitrophenylalanines can be biosynthesized from racemic substrates. The biocatalytic synthesis of the corresponding L-enantiomers is achieved by the reverse reaction, starting from (E)-nitrophenylacrylates. Both enantiomeric products obtained with wt and MIO-less PAL are spectroscopically and chromatog. characterized and their optical rotations measured.

ChemCatChem published new progress about 1772-76-5. 1772-76-5 belongs to catalysis-chemistry, auxiliary class Benzenes, name is (E)-3-(3-Nitrophenyl)acrylic acid, and the molecular formula is C15H21BO2, Computed Properties of 1772-76-5.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia