Trujillo, Cristina’s team published research in European Journal of Organic Chemistry in 2022 | CAS: 2051-95-8

European Journal of Organic Chemistry published new progress about 2051-95-8. 2051-95-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ketone, name is 3-Benzoylpropionicacid, and the molecular formula is C6H12N2O, Product Details of C10H10O3.

Trujillo, Cristina published the artcileMechanistic Insights into the Organocatalytic Kinetic Resolution of Oxazinones through Alcoholysis, Product Details of C10H10O3, the publication is European Journal of Organic Chemistry (2022), 2022(3), e202100818, database is CAplus.

A complete computational study has been performed in order to rationalise the results of a new organocatalytic approach to the kinetic resolution of 4-substituted oxazinones which results in highly enantioenriched and orthogonally-protected ¦Â-amino acids. DFT-anal. elucidated the preferable binding orientation of the 4-oxazinone under study, predicted the formation of the observed major R product with a calculated ee in good agreement with the exptl. data and allowed a complete mechanistic and stereochem. understanding of the catalysis. The alcoholytic kinetic resolution of a 7-memebered ring analog to generate enantioenriched ¦Ã-amino acids was exptl. and computationally investigated for the first time.

European Journal of Organic Chemistry published new progress about 2051-95-8. 2051-95-8 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ketone, name is 3-Benzoylpropionicacid, and the molecular formula is C6H12N2O, Product Details of C10H10O3.

Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia