Journal of Labelled Compounds and Radiopharmaceuticals published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, COA of Formula: C17H37NO3.
Castillo Melean, Johnny published the artcileA three-step radiosynthesis of 6-[18 F]fluoro-L-meta-tyrosine starting with [18 F]fluoride, COA of Formula: C17H37NO3, the publication is Journal of Labelled Compounds and Radiopharmaceuticals (2015), 58(3), 133-140, database is CAplus and MEDLINE.
The radiosynthesis of 6-[18 F]fluoro-L–m-tyrosine has generally been performed by electrophilic radiofluorination, which exhibits several drawbacks. In the present work, a three-step radiochem. synthesis is described starting from [18 F]fluoride. The synthetic sequence, including isotopic exchange, Baeyer-Villiger oxidation, and hydrolysis, were examined comparing four fluorobenzophenone derivatives as labeling precursors. Of those, (2S,5S)-tert-Bu 5-(5-acetyl-2-fluorobenzyl)-2-tert-butyl-3-methyl-4-oxoimidazolidine-1-carboxylate and (2S,5S)-tert-Bu 2-tert-butyl-5-(2-fluoro-5-(2,2,2-trifluoroacetyl)benzyl)-3-methyl-4-oxoimidazolidine-1-carboxylate proved to be the most suitable ones. 6-[18 F]Fluoro-L-m-tyrosine was obtained with overall radiochem. yields of 8-13% and an enantiomeric excess of up to 98%.
Journal of Labelled Compounds and Radiopharmaceuticals published new progress about 17351-62-1. 17351-62-1 belongs to catalysis-chemistry, auxiliary class Salt,Amine, name is Tetrabutylammonium hydrogencarbonate, and the molecular formula is C17H37NO3, COA of Formula: C17H37NO3.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia