Grollier, Kevin published the artcile(Trifluoromethylselenyl)methylchalcogenyl as Emerging Fluorinated Groups: Synthesis under Photoredox Catalysis and Determination of the Lipophilicity, Synthetic Route of 5411-14-3, the publication is Chemistry – A European Journal (2021), 27(19), 6028-6033, database is CAplus and MEDLINE.
The synthesis of mols. bearing (trifluoromethylselenyl)methylchalcogenyl groups ArXCH2COOH (Ar = 4-methylphenyl, 2-methoxy-4-(prop-2-en-1-yl)phenyl, naphthalen-1-yl, etc.; X = O, S, Se) via an efficient two-step strategy based on a metal-free photoredox catalyzed decarboxylative trifluoromethylselenolation with good yields up to 88%, which raised to 98% in flow chem. conditions was described. The flow methods allowed also to scale up the reaction. The mechanism of this key reaction was studied. The physicochem. characterization of these emerging groups was performed by determining their Hansch-Leo lipophilicity parameters with high values up to 2.24. This reaction was also extended to perfluoroalkylselenolation with yields up to 95%. Finally, this method was successfully applied to the functionalization of relevant bioactive mols. such as tocopherol I or estrone derivatives II (R1 = CF3, C6F13).
Chemistry – A European Journal published new progress about 5411-14-3. 5411-14-3 belongs to catalysis-chemistry, auxiliary class Carboxylic acid,Benzene,Ether, name is 2,2-(1,2-Phenylenebis(oxy))diacetic acid, and the molecular formula is C10H10O6, Synthetic Route of 5411-14-3.
Referemce:
https://courses.lumenlearning.com/boundless-chemistry/chapter/catalysis/,
Catalysis – Wikipedia